-
1
-
-
0037032835
-
-
G. Manning, D. B. Whyte, R. Martinez, T. Hunter, S. Sundarsanam, Science 2002, 298, 1912-1934.
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sundarsanam, S.5
-
3
-
-
10744233716
-
-
S. G. O'Brien, F. Guilhot, R. A. Larson, I. Gathmann, M. Baccarani, F. Cervantes, J. J. Cornelissen, T. Fischer, A. Hochhaus, T. Hughes, K. Lechner, J. L. Nielsen, P. Rousselot, J. Reiffers, G. Saglio, J. Shepherd, B. Simonsson, A. Gratwohl, J. M. Goldman, H. Kantarjian, K. Taylor, G. Verhoef, A. E. Bolton, R. Capdeville, B. J. Druker, N. Engl. J. Med. 2003, 348, 1048-1050.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1048-1050
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
Gathmann, I.4
Baccarani, M.5
Cervantes, F.6
Cornelissen, J.J.7
Fischer, T.8
Hochhaus, A.9
Hughes, T.10
Lechner, K.11
Nielsen, J.L.12
Rousselot, P.13
Reiffers, J.14
Saglio, G.15
Shepherd, J.16
Simonsson, B.17
Gratwohl, A.18
Goldman, J.M.19
Kantarjian, H.20
Taylor, K.21
Verhoef, G.22
Bolton, A.E.23
Capdeville, R.24
Druker, B.J.25
more..
-
5
-
-
0031877977
-
-
T. Asano, I. Ikegaki, S. Satoh, M. Seto, Y. Sasaki, Cardiovasc. Drug Rev. 1998, 16, 76-78.
-
(1998)
Cardiovasc. Drug Rev.
, vol.16
, pp. 76-78
-
-
Asano, T.1
Ikegaki, I.2
Satoh, S.3
Seto, M.4
Sasaki, Y.5
-
6
-
-
1642494839
-
-
S. R. Whittaker, M. I. Wallon, M. D. Garrett, P. Workman, Cancer Res. 2004, 64, 262-272.
-
(2004)
Cancer Res.
, vol.64
, pp. 262-272
-
-
Whittaker, S.R.1
Wallon, M.I.2
Garrett, M.D.3
Workman, P.4
-
7
-
-
0037001120
-
-
L. A. Sorbera, J. Castañer, J. Bozzo, P. A. Leeson, Drugs Future 2002, 27, 1141-1147.
-
(2002)
Drugs Future
, vol.27
, pp. 1141-1147
-
-
Sorbera, L.A.1
Castañer, J.2
Bozzo, J.3
Leeson, P.A.4
-
8
-
-
0037313867
-
-
J. Drevs, M. Medinger, C. Schmidt-Gersbach, R. Weber, C. Unger, Curr. Drug Targets 2003, 4, 113-121.
-
(2003)
Curr. Drug Targets
, vol.4
, pp. 113-121
-
-
Drevs, J.1
Medinger, M.2
Schmidt-Gersbach, C.3
Weber, R.4
Unger, C.5
-
9
-
-
18944378492
-
-
D. Maclean, J. J. Baldwin, V. T. Ivanov, Y. Kato, A. Shaw, P. Schneider, E. M. Gordon, Pure Appl. Chem. 1999, 71, 2349-2365.
-
(1999)
Pure Appl. Chem.
, vol.71
, pp. 2349-2365
-
-
Maclean, D.1
Baldwin, J.J.2
Ivanov, V.T.3
Kato, Y.4
Shaw, A.5
Schneider, P.6
Gordon, E.M.7
-
12
-
-
0035924235
-
-
T. Honma, K. Hayashi, T. Aoyama, N. Hashimoto, T. Machida, K. Fukasawa, T. Iwama, C. Ikeura, M. Ikuta, I. Suzuki-Takahashi, Y. Iwasawa, T. Hayama, S. Nishimura, H. Morishima, J. Med. Chem. 2001, 44, 4615-4627.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 4615-4627
-
-
Honma, T.1
Hayashi, K.2
Aoyama, T.3
Hashimoto, N.4
Machida, T.5
Fukasawa, K.6
Iwama, T.7
Ikeura, C.8
Ikuta, M.9
Suzuki-Takahashi, I.10
Iwasawa, Y.11
Hayama, T.12
Nishimura, S.13
Morishima, H.14
-
13
-
-
0036181669
-
-
I. R. Hardcastle, B. T. Golding, R. J. Griffin, Annu. Rev. Pharmacol. Toxicol. 2002, 42, 325-348.
-
(2002)
Annu. Rev. Pharmacol. Toxicol.
, vol.42
, pp. 325-348
-
-
Hardcastle, I.R.1
Golding, B.T.2
Griffin, R.J.3
-
15
-
-
0034306450
-
-
S. P. Davies, H. Reddy, M. Caivano, P. Cohen, Biochem. J. 2000, 351, 95-105.
-
(2000)
Biochem. J.
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
16
-
-
0037032835
-
-
G. Manning, D. B. Whyte, R. Martinez, T. Hunter, S. Sundarsanam, Science 2002, 298, 1912-1934.
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sundarsanam, S.5
-
17
-
-
0036679979
-
-
J. Adams, P. Huang, D. Patrick, Curr. Opin. Chem. Biol. 2002, 6, 486-492.
-
(2002)
Curr. Opin. Chem. Biol.
, vol.6
, pp. 486-492
-
-
Adams, J.1
Huang, P.2
Patrick, D.3
-
18
-
-
0033400589
-
-
F. L. Stahura, L. Xue, J. W. Godden, J. Bajorath, J. Mol. Graphics Modell. 1999, 17, 1-9.
-
(1999)
J. Mol. Graphics Modell.
, vol.17
, pp. 1-9
-
-
Stahura, F.L.1
Xue, L.2
Godden, J.W.3
Bajorath, J.4
-
20
-
-
0033954256
-
-
H. M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T. N. Bhat, H. Weissig, I. N. Shindyalov, P. E. Bourne, Nucleic Acids Res. 2000, 28, 235-242.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
Weissig, H.6
Shindyalov, I.N.7
Bourne, P.E.8
-
21
-
-
0034642482
-
-
L. Shewchuk, A. Hassell, B. Wisely, W. Rocque, W. Holmes, J. Veal, L. F. Kuyper, J. Med. Chem. 2000, 43, 133-139.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 133-139
-
-
Shewchuk, L.1
Hassell, A.2
Wisely, B.3
Rocque, W.4
Holmes, W.5
Veal, J.6
Kuyper, L.F.7
-
22
-
-
0034721195
-
-
C. E. Arris, F. T. Boyle, A. H. Calvert, N. J. Curtin, J. A. Endicott, E. F. Carman, A. E. Gibson, B. T. Golding, S. Grant, R. J. Griffin, P. Jewsbury L. N. Johnson, A. M. Lawrie, D. R. Newell, M. E. M. Noble, E. A. Sausville, R. Schultz, W. Yu, J. Med. Chem. 2000, 43, 2797-2804.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 2797-2804
-
-
Arris, C.E.1
Boyle, F.T.2
Calvert, A.H.3
Curtin, N.J.4
Endicott, J.A.5
Carman, E.F.6
Gibson, A.E.7
Golding, B.T.8
Grant, S.9
Griffin, R.J.10
Jewsbury, P.11
Johnson, L.N.12
Lawrie, A.M.13
Newell, D.R.14
Noble, M.E.M.15
Sausville, E.A.16
Schultz, R.17
Yu, W.18
-
23
-
-
0034710707
-
-
A. Wissner, D. M. Berger, D. H. Boschelli, M. B. Floyd, L. M. Greenberger, B. C. Gruber, B. D. Johnson, N. Mamuya, R. Nilakantan, M. F. Reich, R. Shen, H.-R. Tsou, E. Upesacis, Y. F. Wang, B. Wu, F. Ye, N. Zhang, J. Med. Chem. 2000, 43, 3244-3256.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 3244-3256
-
-
Wissner, A.1
Berger, D.M.2
Boschelli, D.H.3
Floyd, M.B.4
Greenberger, L.M.5
Gruber, B.C.6
Johnson, B.D.7
Mamuya, N.8
Nilakantan, R.9
Reich, M.F.10
Shen, R.11
Tsou, H.-R.12
Upesacis, E.13
Wang, Y.F.14
Wu, B.15
Ye, F.16
Zhang, N.17
-
24
-
-
0030945871
-
-
M. Mohammadi, G. McMahon, L. Sun, P. C. Tang, P. Hirth, B. K. Yeh, S. R. Hubbard, J. Schlessinger, Science 1997, 276, 955-960.
-
(1997)
Science
, vol.276
, pp. 955-960
-
-
Mohammadi, M.1
McMahon, G.2
Sun, L.3
Tang, P.C.4
Hirth, P.5
Yeh, B.K.6
Hubbard, S.R.7
Schlessinger, J.8
-
25
-
-
0033152210
-
-
X. Zhu, J. L. Kim, J. R. Newcomb, P. E. Rose, Structure 1999, 7, 651-661.
-
(1999)
Structure
, vol.7
, pp. 651-661
-
-
Zhu, X.1
Kim, J.L.2
Newcomb, J.R.3
Rose, P.E.4
-
26
-
-
0032563315
-
-
N. S. Gray, L. Wodicka, A.-M. W. H. Thunnissen, T. C. Norman, S. Kwon, F. H. Espinoza, D. O. Morgan, G. Barnes, S. LeClerc, L. Meijer, S.-H. Kim, D. J. Lockart, P. G. Schultz, Science 1998, 281, 533-538.
-
(1998)
Science
, vol.281
, pp. 533-538
-
-
Gray, N.S.1
Wodicka, L.2
Thunnissen, A.-M.W.H.3
Norman, T.C.4
Kwon, S.5
Espinoza, F.H.6
Morgan, D.O.7
Barnes, G.8
Leclerc, S.9
Meijer, L.10
Kim, S.-H.11
Lockart, D.J.12
Schultz, P.G.13
-
27
-
-
0037194619
-
-
K. S. Kim, S. D. Kimball, R. N. Misra, D. B. Rawlins, J. T. Hunt, H.-Y. Xiao, S. Lu, L. Qian, W. C. Han, W. Shan, T. Mitt, Z.-W. Cai, M. A. Poss, H. Zhu, J. S. Sack, J. S. Tokarski, C. Y. Chang, N. Pavletich, A. Kamath, W. G. Humphreys, P. Marathe, I. Bursuker, K. A. Kellar, U. Roongta, R. Batorsky, J. G. Mulheron, D. Bol, C. R. Fairchild, F. Y. Lee, K. R. Webster, J. Med. Chem. 2002, 45, 3905-3927.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 3905-3927
-
-
Kim, K.S.1
Kimball, S.D.2
Misra, R.N.3
Rawlins, D.B.4
Hunt, J.T.5
Xiao, H.-Y.6
Lu, S.7
Qian, L.8
Han, W.C.9
Shan, W.10
Mitt, T.11
Cai, Z.-W.12
Poss, M.A.13
Zhu, H.14
Sack, J.S.15
Tokarski, J.S.16
Chang, C.Y.17
Pavletich, N.18
Kamath, A.19
Humphreys, W.G.20
Marathe, P.21
Bursuker, I.22
Kellar, K.A.23
Roongta, U.24
Batorsky, R.25
Mulheron, J.G.26
Bol, D.27
Fairchild, C.R.28
Lee, F.Y.29
Webster, K.R.30
more..
-
28
-
-
0034736093
-
-
M. Barvian, D. H. Boschelli, J. Cossrow, E. Dobrusin, A. Fattaey, A. Fritsch, D. Fry, P. Harvey, P. Keller, M. Garrett, F. La, W. Leopold, D. McNamara, M. Quin, S. Trumpp-Kallmeyer, P. Toogood, Z. Wu, E. Zhang, J. Med. Chem. 2000, 43, 4606-4616.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 4606-4616
-
-
Barvian, M.1
Boschelli, D.H.2
Cossrow, J.3
Dobrusin, E.4
Fattaey, A.5
Fritsch, A.6
Fry, D.7
Harvey, P.8
Keller, P.9
Garrett, M.10
La, F.11
Leopold, W.12
McNamara, D.13
Quin, M.14
Trumpp-Kallmeyer, S.15
Toogood, P.16
Wu, Z.17
Zhang, E.18
-
30
-
-
1642295074
-
-
T. L. Underiner, B. Ruggeri, D. E. Gingrich, Curr. Med. Chem. 2004, 11, 731-745;
-
(2004)
Curr. Med. Chem.
, vol.11
, pp. 731-745
-
-
Underiner, T.L.1
Ruggeri, B.2
Gingrich, D.E.3
-
31
-
-
4544308575
-
-
A. Huwe, R. Mazitschek, A. Giannis, Angew. Chem. 2003, 115, 2170-2187;
-
(2003)
Angew. Chem.
, vol.115
, pp. 2170-2187
-
-
Huwe, A.1
Mazitschek, R.2
Giannis, A.3
-
32
-
-
0038245253
-
-
Angew. Chem. Int. Ed. 2003, 42, 2122-2138;.
-
(2003)
Angew. Chem. Int. Ed.
, vol.42
, pp. 2122-2138
-
-
-
33
-
-
20944441773
-
-
http://www.icr.ac.uk/education/studentships/collins.html
-
-
-
-
35
-
-
20944440991
-
-
Modern Drug Data Report database is distributed by MDL Information Systems, San Leandro, CA (USA)
-
Modern Drug Data Report database is distributed by MDL Information Systems, San Leandro, CA (USA).
-
-
-
-
37
-
-
0034632795
-
-
M. A. Kastenholz, M. Pastor, G. Cruciani, E. E. J. Haaksma, T. Fox, J. Med. Chem. 2000, 43, 3033-3044.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 3033-3044
-
-
Kastenholz, M.A.1
Pastor, M.2
Cruciani, G.3
Haaksma, E.E.J.4
Fox, T.5
-
40
-
-
20944446409
-
-
http://www.bioscreening.com/targeted_libraries.htm
-
-
-
-
41
-
-
20944434028
-
-
http://www.drugdesign.com/services.html
-
-
-
-
42
-
-
20944432626
-
-
http://www.scynexis.com/
-
-
-
-
43
-
-
20944432372
-
-
http://www.biofocus.com/pages/prod_kinase_target_alli.mhtml
-
-
-
-
44
-
-
20944445563
-
-
WO2003004147(A2), WO9926901
-
WO2003004147(A2), WO9926901.
-
-
-
-
45
-
-
20944441661
-
-
http://www.chemdiv.com/discovery/libraries1.phtml
-
-
-
-
47
-
-
20944441221
-
-
http://www.timtec.net/products/actimol.htm
-
-
-
-
48
-
-
20944436720
-
-
http://www.leaddiscovery.co.uk/reports/Kinase-inhibitors.html
-
-
-
-
49
-
-
20944436194
-
-
http://www.asinex.com/prod/targ.html
-
-
-
-
50
-
-
20944437695
-
-
http://www.ibscreen.com/highhit.shtml
-
-
-
-
51
-
-
20944440871
-
-
http://www.enamine.relc.com/en/targeted.html
-
-
-
-
52
-
-
20944449584
-
-
http://www.enamine.relc.com/en/tlgen2.html
-
-
-
-
53
-
-
20944440993
-
-
http://www.specs.net
-
-
-
-
54
-
-
20944450698
-
-
http://www.chembridge.com/chembridge/combinatorial_libraries.html
-
-
-
-
55
-
-
20944451007
-
-
http://www.iflab.kiev.ua/eng/about/news/215/
-
-
-
-
56
-
-
20944449831
-
-
http://www.iflab.kiev.ua/eng/downloads/149/
-
-
-
-
57
-
-
20944450186
-
-
http://www.pharmacopeia.com/dcs/libs.html
-
-
-
-
58
-
-
20944438450
-
-
http://www.advsyntech.com/focused.htm
-
-
-
-
59
-
-
20944451006
-
-
abstract and proceedings from a referenced presentation, held in May 2002 in Bozen (Italy)
-
http://www.beilstein-institut.de/; abstract and proceedings from a referenced presentation, held in May 2002 in Bozen (Italy), can be accessed through the event archive; http://www.beilstein-institut.de/bozen2002/ proceedings/baringhaus/baringhaus.html
-
-
-
|