Atypical pharmacokinetics and excretion of new platinum analogues in rodents

Cancer Chemotherapy and Pharmacology

Volumn 49, Issue 1, 2002, Pages 87-92

  Webster, Lorraine K ^a,c,d   Ellis, Andrew G ^a,c,d   Apicella, Carmel ^a,c,d   Deacon, Glen B ^b,c,d  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c Faulding Pharmaceuticals   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Biliary clearance; Excretion; Pharmacokinetics; Platinum

Indexed keywords

ARACHIS OIL; CARBOPLATIN; CISPLATIN; DIMETHYL SULFOXIDE; PLATINUM COMPLEX; POLYSORBATE 20; SODIUM CHLORIDE; DRUG VEHICLE; PLASMA PROTEIN; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BILE; BLOOD SAMPLING; CANCER COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG EXCRETION; DRUG FECES LEVEL; DRUG URINE LEVEL; FECES ANALYSIS; FEMALE; ISOLATED LIVER; LIVER PERFUSION; MALE; MOUSE; NONHUMAN; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; RAT; TOXICITY; URINALYSIS; URINARY EXCRETION; ANIMAL MODEL; CYTOTOXICITY; DOSE RESPONSE; DRUG PROTEIN BINDING; LIVER; RODENT;

ANIMALS; ANTINEOPLASTIC AGENTS; AREA UNDER CURVE; BILE; CISPLATIN; FEMALE; LIVER; MALE; MICE; MICE, INBRED BALB C; ORGANOPLATINUM COMPOUNDS; PLATINUM; RATS; RATS, SPRAGUE-DAWLEY;

EID: 20444447047     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-001-0381-7     Document Type: Article

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