Pharm profile: Flumazenil

Compendium on Continuing Education for the Practicing Veterinarian

Volumn 27, Issue 5, 2005, Pages

  Smith, Jason P ^a   Volmer, Petra A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 20444432333     PISSN: 01931903     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

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3. Bertini S: Benzodiazepine poisoning in companion animals. Vet Hum Toxicol 37(6):559-562, 1995.
4. Roche Pharmaceuticals Web site: Romazicon (flumazenil) injection complete product information. Available at www.rocheusa.com/products/romazicon/; accessed March 2003.
5. Lemke KA, Tranquilli WJ, Thurmon JC, et al: Ability of flumazenil, butorphanol, and naloxone to reverse the anesthetic effects of oxymorphone-diazepam in dogs. JAVMA 209(4):775-779, 1996.
6. Tranquilli WJ, Gross ME, Thurmon JC, et al: Evaluation of three midazolam-xylazine mixtures: Preliminary trials in dogs. Vet Surg 19(2):168-172, 1990.
7. Gross ME, Tranquilli WJ, Thurmon JC, et al: Yohimbme/flumazenil antagonism of hemodynamic alterations induced by a combination of midazolam, xylazine, and butorphanol in dogs. JAVMA 201(12):1887-1890, 1992.
8. Rang HP, Dale MM, Ritter JM, et al: Pharmacology, ed 5. New York, Churchill Livingstone, 2003.
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10. Howland MA: Antidotes in depth, in Goldfrank LR, Flomenbaum NE, Lewin NA, et al (eds): Goldfrank's Toxicologic Emergencies, ed 6. New York, Appleton & Lange, 1998, pp 1017-1020.
11. Plumb DC: Veterinary Drug Handbook, ed 4. Ames, Iowa State University Press, 2002.
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14. Reves JG, Glass PS, Lubarsky DA: Anesthesia, ed 4. New York, Churchill Livingstone, 1994.
15. Ilkiw JE, Farver TB, Suter C, et al: The effect of intravenous administration of variable-dose flumazenil after fixed-dose ketamine and midazolam in healthy cats. J Vet Pharmacol Ther 25(3):181-188, 2002.
16. Bossman DK, Van den Buijs CACG, De Haan JC, et al: The effects of benzodiazepine-receptor antagonists and partial inverse agonist on acute hepatic encephalopathy in the rat. Gastroenterology 101(3):772-781, 1991.
17. Van der Rijt CC, de Knegt RJ, Schalm SW, et al: Flumazenil does not improve hepatic encephalopathy associated with acute ischemic liver failure in the rabbit. Metab Brain Dis 5(3):131-141, 1990.
18. Meyer HP, Legemate DA, Brom W, et al: Improvement of chronic hepatic encephalopathy in dogs by the benzodiazepine-receptor partial inverse agonist sarmazenil but not by the antagonist flumazenil. Metab Brain Dis 13(3):241-251, 1998.
19. Schlappi B, Bonetti EP, Burgin H, et al: Toxicological investigations with the benzodiazepine antagonist flumazenil. Arzneimittelforschung 38(2):247-250, 1988.
20. Lheureux P, Vranckx M, Leduc D, et al: Flumazenil in mixed benzodiazepine/tricyclic antidepressant overdose: A placebo-controlled study in the dog. Am J Emerg Med 10(3):184-188, 1992.