Therapeutic capacity of the synthetic peptide-based vaccine against Taenia solium cysticercosis in pigs

Vaccine

Volumn 23, Issue 31, 2005, Pages 4062-4069

  De Aluja, Aline S ^a   Villalobos, Nelly M ^a   Nava, Gabriela ^a   Toledo, Andrea ^a   Martínez, José Juan ^a   Plancarte, Agustín ^b   Rodarte, Luis Felipe ^a   Fragoso, Gladis ^a   Sciutto, Edda ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Pig cysticercosis; Protection; Taenia solium; Therapeutic vaccine

Indexed keywords

ALANYLPROLYLMETHIONYLSERYLTHREONYLPROLYLSERYLALANYLTHREONYLSERYLVALYL THREONINE; GLYCYLASPARAGINYLLEUCYLLEUCYLLEUCYLSERYLCYSTEINYLLEUCINE; GLYCYLTYROSYLTYROSYLTYROSYLPROLYLSERYLASPARTYLPROLYLASPARAGINYLTHREONYL PHENYLALANYLTYROSYLALANYLPROLYLPROLYLTYROSYLSERYLALANINE; PARASITE ANTIBODY; SYNTHETIC PEPTIDE; SYNTHETIC THREE PEPTIDE VACCINE; UNCLASSIFIED DRUG; VACCINE;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; CYSTICERCOSIS; DRUG EFFICACY; FEMALE; MALE; MUSCLE; NEUROCYSTICERCOSIS; NONHUMAN; PRIORITY JOURNAL; SWINE; TAENIA SOLIUM;

ANIMALS; ANTIBODIES, HELMINTH; CRICETINAE; CYSTICERCOSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; LEUKOCYTES, MONONUCLEAR; MALE; MUSCLES; SWINE; SWINE DISEASES; TAENIA SOLIUM; VACCINES, SUBUNIT; VACCINES, SYNTHETIC;

EID: 20444428292     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2004.11.076     Document Type: Article

References (19)

1. N.M. Keilbach, A.S. de Aluja, and E. Sarti-Gutierrez A programme to control taeniasis-cysticercosis (Taenia solium): experiences in a Mexican village Acta Leidensia 57 1989 181 189
2. A. Fleury, T. Gomez, I. Alvarez, D. Meza, M. Huerta, and A. Chavarria High prevalence of calcified silent neurocysticercosis in a rural village of Mexico Neuroepidemiology 22 2003 139 145
3. A.S. de Aluja Frecuency of porcine cysticercosis in Mexico A. Flisser K. Willms J.P. Laclette C. Larralde C. Ridaura F. Beltran Cysticercosis: present state of knowledge and perspectives 1982 Academic Press New York 53 62
4. J.L. Molinari, D. Rodriguez, P. Tato, R. Soto, F. Arechavaleta, and S. Solano Field trial for reducing porcine Taenia solium cysticercosis in Mexico by systematic vaccination of pigs Vet Parasitol 69 1997 55 63
5. A. Plancarte, A. Flisser, C.G. Gauci, and M.W. Lightowlers Vaccination against Taenia solium cysticercosis in pigs using native and recombinant oncosphere antigens Int J Parasitol 9 1999 643 664
6. M. Huerta, A.S. de Aluja, G. Fragoso, A. Toledo, N. Villalobos, and M. Hernández Synthetic peptide vaccine against Taenia solium pig cysticercosis: successful vaccination in a controlled field trial in rural Mexico Vaccine 20 2001 262 266
7. L.A. Babiuk Vaccination: a management tool in veterinary medicine Vet J 164 3 2002 188 201
8. M.W. Lightowlers Vaccines for prevention of cysticercosis Acta Trop 87 1 2003 129 135
9. E. Sciutto, J.J. Martinez, M. Huerta, R. Avila, G. Fragoso, and N. Villalobos Familial clustering of Taenia solium cysticercosis in the rural pigs of Mexico: hints of genetic determinants in innate and acquired resistance to infection Vet Parasitol 116 3 2003 223 229
10. G. García, E. Sciutto, G. Fragoso, C. Cruz, A. Toledo, and N. Villalobos Inhibitory role of antibodies in the development of Taenia solium and Taenia crassiceps towards reproductive and pathogenic stages J. Parasitol 87 2001 582 586
11. M.A. Díaz, N. Villalobos, A.S. de Aluja, G. Rosas, E. Gómez-Conde, and P. Hernández Th1 and Th2 indices of the immune response in pigs vaccinated against Taenia solium cysticercosis suggest various host immune strategies against the parasite Vet Immunol Immunopathol 93 3-4 2003 81 90
12. E. Santamaria, A. Plancarte, and A.S. de Aluja The experimental infection of pigs with different numbers of Taenia solium eggs: immune response and efficiency of establishment J Parasitol 88 1 2002 69 73
13. A.S. de Aluja, and G. Vargas The histopathology of porcine cysticercosis Veterinary Parasitology 28 1988 65 77
14. V.C. Tsang, J. Brand, and E. Boyer Enzyme-linked immunoelectrotransferency blot assay and glycoprotein antigens for diagnosing human cysticercosis J Infect Dis 159 1989 50 59
15. V. Tsang, A.J. Pilcher, W. Zhow, E.A. Boyer, Kamango-Sollo IPE, and L.M. Rhoads Efficacy of the immunoblot assay for cysticercosis in pigs and modulated expression of distinct IgM/IgG activities to Taenia solium antigens in experimental infections Vet Immunol Immunopathol 29 1991 69 78
16. J.L. Molinari, H. Mejia, A.C. White Jr., E. Garrido, V.M. Borgonio, and S. Baig Taenia solium: a cysteine protease secreted by metacestodes depletes human CD4 lymphocytes in vitro Exp Parasitol 94 3 2000 133 142
17. A.S. de Aluja, A.N. Villalobos, A. Plancarte, L.F. Rodarte, M. Hernandez, and E. Sciutto Experimental Taenia solium cysticercosis in pigs: characteristics of the infection and antibody response Vet Parasitol 61 1996 49 59
18. P.J. Serrano, A.S. de Aluja, L.J. Lecunberri, and A.N. Villalobos Comparación de la reacción inflamatoria causada por el metacestodo de Taenia solium en músculos y encéfalos de cerdos Rev Vet Méx 28 1997 1 5
19. A.S. de Aluja, A.N. Villalobos, A. Plancarte, L.F. Rodarte, M. Hernandez, and C. Zamora Taenia solium cysticercosis: Immunity in pigs induced by primary infection Vet Parasitol 81 1999 129 135