A potency assay for a replication incompetent adenovirus type 5 carrying a human fgf-4 gene

Analytical Biochemistry

Volumn 342, Issue 1, 2005, Pages 34-44

  Fawaz, Farah S ^a   Elsheikh, Moutasem A ^a   Ogawa, Yasushi ^a   Files, Jim G ^a   McCaman, Michael T ^a   Pungor Jr , Erno ^a  

^a BAYER AG   (Germany)

Author keywords

Ad5FGF 4; ARPE 19 cells; Parallel line analysis; Potency assay

Indexed keywords

CELL PROLIFERATION; CELLS; VIRUSES;

AD5FGF-4; CELLULAR PROLIFERATIONS; DOSE-RESPONSE CURVES; ENZYME LINKED IMMUNOSORBENT ASSAY; PARALLEL LINE; POTENCY ASSAY; REFERENCE STANDARD; RELATIVE POTENCIES;

CYTOLOGY;

ADENOVIRUS VECTOR; BASIC FIBROBLAST GROWTH FACTOR; BETA GALACTOSIDASE; FIBROBLAST GROWTH FACTOR 4; SOMATOMEDIN;

ADENOVIRUS 5; ARTICLE; BIOASSAY; CELL COUNT; CELL GROWTH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MICROTITER PLATE ASSAY; PIGMENT CELL; PRIORITY JOURNAL; TRANSGENE;

HUMAN ADENOVIRUS TYPE 5;

EID: 20444410048     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2005.04.001     Document Type: Article

References (16)

1. E.F. Unger, S. Banai, M. Shou, M. Jaklitsch, E. Hodge, R. Correa, M. Jaye, and S.E. Epstein A model to assess interventions to improve collateral blood flow: continuous administration of agents into the left coronary artery in dogs Cardiovasc. Res. 27 1993 785 791
2. F.J. Giordano, P. Ping, M.D. McKirman, S. Nozaki, A.N. DeMaria, W.H. Dillmann, O. Mathieu-Costello, and H.K. Hammond Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in the ischemic region of the heart Nat. Med. 2 1996 534 539
3. K. Harada, W. Grossman, M. Friedman, E.R. Edelman, P.V. Prasad, C.S. Keighley, W.J. Manning, F.W. Sellke, and M. Simons Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts J. Clin. Invest. 94 1994 623 630
4. J. Folkman, and M. Klagsburn Angiogenic factors Science 235 1987 442 447
5. D.B. Rifkin, and D. Moscatelli Recent developments in the cell biology of basic fibroblast growth factor J. Cell Biol. 109 1989 1 6
6. M. Klagsbrun The fibroblast growth factor family: structural and biological properties Prog. Growth Factor Res. 1 1989 207 235
7. A. Baird Fibroblast growth factors: activities and significance of non-neurotrophin neurotrophic growth factor Curr. Opin. Neurobiol. 4 1994 78 86
8. C. Grines, G.M. Rubanyi, N.S. Kleiman, P. Marrott, and M.W. Watkins Angiogenic gene therapy with adenovirus 5 fibroblast growth factor-4 (Ad5FGF-4): a new option for the treatment of coronary artery disease Am. J. Cardiol. 92 2003 24 31
9. B.G. Huyghe, X. Liu, S. Sutjipto, B.J. Sugarman, M.T. Horn, H.M. Shepard, C.J. Scandella, and P. Shabram Purification of a type 5 recombinant adenovirus encoding human p53 by column chromatography Hum. Gene Ther. 6 1995 1403 1416
10. E. Lehmberg, J.A. Traina, J.A. Chakel, R.J. Chang, M. Parkman, M.T. McCaman, P.K. Murakami, V. Lahidji, J.W. Nelson, W.S. Hancock, E. Nestaas, and E. Pungor Jr. Reversed-phase high performance liquid chromatographic assay for the adenovirus type 5 proteome J. Chromatogr. B Biomed. Sci. Appl. 732 1999 411 423
11. P. Murakami, M. Havenga, F. Fawaz, R. Vogels, G. Marzio, E. Pungor, J. Files, L. Do, J. Goudsmit, and M. McCaman Common structure of rare replication-deficient E1-positive particles in adenoviral vector batches J. Virol. 78 2004 6200 6208
12. K.C. Dunn, A.E. Aotaki-Kee, F.R. Putkey, and L.M. Hjelmeland ARPE-19, a human retinal pigment epithelial cell line with differentiated properties Exp. Eye Res. 62 1996 155 169
13. J.N. Harada, and A.J. Berk P53-independent and dependent requirements for E1B-55K in adenovirus type 5 replication J. Virol. 73 1999 5333 5344
14. S. Teramoto, T. Matsuse, H. Matsui, E. Ohga, T. Ishii, T. Nagase, and Y. Ouchi Recombinant E1-deleted adenoviral vectors induce apoptosis in a rat airway epithelial mucous goblet cell line Jpn. J. Pharmacol. 81 1999 73 78
15. R.P. Wersto, E.R. Rosenthal, P.K. Seth, N.T. Eissa, and R.E. Donahue Recombinant,replication-defective adenovirus gene transfer vectors induce cell cycle dysregulation and inappropriate expression of cyclin proteins J. Virol. 72 1998 9491 9502
16. D. Aviezer, M. Safran, and A. Yayon Heparin differentially regulates the interaction of fibroblast growth factor-4 with FGF receptors 1 and 2 Biochem. Biophys. Res. Commun. 263 1999 621 626