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Volumn 383, Issue 3, 2005, Pages 328-332

Stepholidine protects against H2O2 neurotoxicity in rat cortical neurons by activation of Akt

Author keywords

PI3 K Akt; SPD; SZ

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; HYDROGEN PEROXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; STEPHOLIDINE; 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; AKT1 PROTEIN, RAT; BERBERINE; CHROMONE DERIVATIVE; DOPAMINE RECEPTOR BLOCKING AGENT; DRUG DERIVATIVE; ENZYME INHIBITOR; HALOPERIDOL; MORPHOLINE DERIVATIVE; NEUROPROTECTIVE AGENT; ONCOPROTEIN; SK&F 83566;

EID: 20444408385     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.04.016     Document Type: Article
Times cited : (26)

References (31)
  • 1
    • 0141788413 scopus 로고    scopus 로고
    • Prefrontal DA transmission at D1 receptors and the pathology of schizophrenia
    • A. Abi-Dargham, and H. Moore Prefrontal DA transmission at D1 receptors and the pathology of schizophrenia Neuroscientist 9 2003 404 416
    • (2003) Neuroscientist , vol.9 , pp. 404-416
    • Abi-Dargham, A.1    Moore, H.2
  • 2
    • 0041430890 scopus 로고    scopus 로고
    • Anti-proliferative effects and cell death mediated by two isoforms of dopamine D2 receptors in pituitary tumor cells
    • J.J. An, S.R. Cho, D.W. Jeong, K.W. Park, Y.S. Ahn, and J.H. Baik Anti-proliferative effects and cell death mediated by two isoforms of dopamine D2 receptors in pituitary tumor cells Mol. Cell. Endocrinol. 206 2003 49 62
    • (2003) Mol. Cell. Endocrinol. , vol.206 , pp. 49-62
    • An, J.J.1    Cho, S.R.2    Jeong, D.W.3    Park, K.W.4    Ahn, Y.S.5    Baik, J.H.6
  • 3
    • 0016739986 scopus 로고
    • Opium alkaloids XV: Isolation of stepholidine
    • E. Brochmann-Hanssen, and W.J. Richter Opium alkaloids XV: isolation of stepholidine J. Pharm. Sci. 64 1975 1040 1041
    • (1975) J. Pharm. Sci. , vol.64 , pp. 1040-1041
    • Brochmann-Hanssen, E.1    Richter, W.J.2
  • 4
    • 0022613311 scopus 로고
    • Analgesic and antipyretic effects of l-stepholidine without addiction
    • L.F. Chen, J.Z. Gao, and F.C. Wang Analgesic and antipyretic effects of l-stepholidine without addiction Zhongguo Yao Li Xue Bao 7 1986 311 314
    • (1986) Zhongguo Yao Li Xue Bao , vol.7 , pp. 311-314
    • Chen, L.F.1    Gao, J.Z.2    Wang, F.C.3
  • 5
    • 0021886241 scopus 로고
    • Analgesic, sedative and antispastic effects of l-stepholidine
    • L.F. Chen, J.Z. Gao, F.C. Wang, and C.R. Yang Analgesic, sedative and antispastic effects of l-stepholidine Zhongguo Yao Li Xue Bao 6 1985 156 158
    • (1985) Zhongguo Yao Li Xue Bao , vol.6 , pp. 156-158
    • Chen, L.F.1    Gao, J.Z.2    Wang, F.C.3    Yang, C.R.4
  • 6
    • 11144308859 scopus 로고    scopus 로고
    • Activating Akt and the brain's resources to drive cellular survival and prevent inflammatory injury
    • Z.Z. Chong, F. Li, and K. Maiese Activating Akt and the brain's resources to drive cellular survival and prevent inflammatory injury Histol. Histopathol. 20 2005 299 315
    • (2005) Histol. Histopathol. , vol.20 , pp. 299-315
    • Chong, Z.Z.1    Li, F.2    Maiese, K.3
  • 8
    • 0030741275 scopus 로고    scopus 로고
    • Dual actions of (-)-stepholidine on the dopamine receptor-mediated adenylate cyclase activity in rat corpus striatum
    • Z.J. Dong, X. Guo, L.J. Chen, Y.F. Han, and G.Z. Jin Dual actions of (-)-stepholidine on the dopamine receptor-mediated adenylate cyclase activity in rat corpus striatum Life Sci. 61 1997 465 472
    • (1997) Life Sci. , vol.61 , pp. 465-472
    • Dong, Z.J.1    Guo, X.2    Chen, L.J.3    Han, Y.F.4    Jin, G.Z.5
  • 9
    • 0025004471 scopus 로고
    • Hypotensive action of l-stepholidine in relation of dopamine receptors
    • T.H. Gu, Z.Y. Zhang, and K.R. Zhou Hypotensive action of l-stepholidine in relation of dopamine receptors Zhongguo Yao Li Xue Bao 11 1990 445 449
    • (1990) Zhongguo Yao Li Xue Bao , vol.11 , pp. 445-449
    • Gu, T.H.1    Zhang, Z.Y.2    Zhou, K.R.3
  • 10
    • 0037113353 scopus 로고    scopus 로고
    • (-)-Stepholidine promotes proliferation and neuronal differentiation of rat embryonic striatal precursor cells in vitro
    • H. Guo, Y. Yu, L. Xing, G.Z. Jin, and J. Zhou (-)-Stepholidine promotes proliferation and neuronal differentiation of rat embryonic striatal precursor cells in vitro Neuroreport 13 2002 2085 2089
    • (2002) Neuroreport , vol.13 , pp. 2085-2089
    • Guo, H.1    Yu, Y.2    Xing, L.3    Jin, G.Z.4    Zhou, J.5
  • 11
    • 0002496195 scopus 로고    scopus 로고
    • Enhancement of (-)-stepholidine on protein phosphorylation of a dopamine- and cAMP-regulated phosphoprotein in denervated striatum of oxidopamine-lesioned rats
    • X. Guo, J. Liu, L.L. Zou, J. Jin, B.C. Wang, and G.Z. Jin Enhancement of (-)-stepholidine on protein phosphorylation of a dopamine- and cAMP-regulated phosphoprotein in denervated striatum of oxidopamine-lesioned rats Zhongguo Yao Li Xue Bao 19 1998 100 103
    • (1998) Zhongguo Yao Li Xue Bao , vol.19 , pp. 100-103
    • Guo, X.1    Liu, J.2    Zou, L.L.3    Jin, J.4    Wang, B.C.5    Jin, G.Z.6
  • 12
    • 0026598479 scopus 로고
    • Antagonism of l-stepholidine on D2 receptor-mediated inhibition of synaptosomal adenylate cyclase in rat corpus striatum
    • G. Hu, Y. Hu, and G.Z. Jin Antagonism of l-stepholidine on D2 receptor-mediated inhibition of synaptosomal adenylate cyclase in rat corpus striatum Zhongguo Yao Li Xue Bao 13 1992 104 110
    • (1992) Zhongguo Yao Li Xue Bao , vol.13 , pp. 104-110
    • Hu, G.1    Hu, Y.2    Jin, G.Z.3
  • 13
    • 0029028429 scopus 로고
    • (-)-Stepholidine antagonizes the inhibition by D2 receptor agonists on synaptosomal tyrosine hydroylase in rat corpus striatum
    • G. Hu, and G.Z. Jin (-)-Stepholidine antagonizes the inhibition by D2 receptor agonists on synaptosomal tyrosine hydroylase in rat corpus striatum Zhongguo Yao Li Xue Bao 16 1995 376 379
    • (1995) Zhongguo Yao Li Xue Bao , vol.16 , pp. 376-379
    • Hu, G.1    Jin, G.Z.2
  • 14
    • 1442264399 scopus 로고    scopus 로고
    • Apoptotic proteins in the temporal cortex in schizophrenia: High Bax/Bcl-2 ratio without caspase-3 activation
    • L.F. Jarskog, E.S. Selinger, J.A. Lieberman, and J.H. Gilmore Apoptotic proteins in the temporal cortex in schizophrenia: high Bax/Bcl-2 ratio without caspase-3 activation Am. J. Psychiatry 161 2004 109 115
    • (2004) Am. J. Psychiatry , vol.161 , pp. 109-115
    • Jarskog, L.F.1    Selinger, E.S.2    Lieberman, J.A.3    Gilmore, J.H.4
  • 15
    • 0026606730 scopus 로고
    • Dual actions of (-)-stepholidine on dopamine receptor subtypes after substantia nigra lesion
    • G.Z. Jin, K.X. Huang, and B.C. Sun Dual actions of (-)-stepholidine on dopamine receptor subtypes after substantia nigra lesion Neurochem. Int. 20 Suppl. 1992 175S 178S
    • (1992) Neurochem. Int. , vol.20 , Issue.SUPPL.
    • Jin, G.Z.1    Huang, K.X.2    Sun, B.C.3
  • 16
    • 0022717010 scopus 로고
    • Tetrahydroprotoberberine - A new chemical type of antagonist of dopamine receptors
    • G.Z. Jin, X.L. Wang, and W.X. Shi Tetrahydroprotoberberine - a new chemical type of antagonist of dopamine receptors Sci. Sin. [B] 29 1986 527 534
    • (1986) Sci. Sin. [B] , vol.29 , pp. 527-534
    • Jin, G.Z.1    Wang, X.L.2    Shi, W.X.3
  • 17
    • 0036162683 scopus 로고    scopus 로고
    • (-)-Stepholidine: A potential novel antipsychotic drug with dual D1 receptor agonist and D2 receptor antagonist actions
    • G.Z. Jin, Z.T. Zhu, and Y. Fu (-)-Stepholidine: a potential novel antipsychotic drug with dual D1 receptor agonist and D2 receptor antagonist actions Trends Pharmacol. Sci. 23 1 2002 4 7
    • (2002) Trends Pharmacol. Sci. , vol.23 , Issue.1 , pp. 4-7
    • Jin, G.Z.1    Zhu, Z.T.2    Fu, Y.3
  • 18
    • 0345690100 scopus 로고    scopus 로고
    • Half a century of antipsychotics and still a central role for dopamine D2 receptors
    • S. Kapur, and D. Mamo Half a century of antipsychotics and still a central role for dopamine D2 receptors Prog. Neuropsychopharmacol. Biol. Psychiatry 27 2003 1081 1090
    • (2003) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.27 , pp. 1081-1090
    • Kapur, S.1    Mamo, D.2
  • 19
    • 0344875505 scopus 로고    scopus 로고
    • Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor
    • V.D. Nair, and S.C. Sealfon Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor J. Biol. Chem. 278 2003 47053 47061 (Epub 2003 September 11)
    • (2003) J. Biol. Chem. , vol.278 , pp. 47053-47061
    • Nair, V.D.1    Sealfon, S.C.2
  • 20
    • 0031214452 scopus 로고    scopus 로고
    • Attenuation of oxidative neuronal necrosis by a dopamine D1 agonist in mouse cortical cell cultures
    • J.S. Noh, and B.J. Gwag Attenuation of oxidative neuronal necrosis by a dopamine D1 agonist in mouse cortical cell cultures Exp. Neurol. 146 1997 604 608
    • (1997) Exp. Neurol. , vol.146 , pp. 604-608
    • Noh, J.S.1    Gwag, B.J.2
  • 21
    • 0021676610 scopus 로고
    • Effect of l-stepholidine on rotational behavior in rats
    • W.X. Shi, Y. Chen, and G.Z. Jin Effect of l-stepholidine on rotational behavior in rats Zhongguo Yao Li Xue Bao 5 1984 222 225
    • (1984) Zhongguo Yao Li Xue Bao , vol.5 , pp. 222-225
    • Shi, W.X.1    Chen, Y.2    Jin, G.Z.3
  • 22
    • 0026949248 scopus 로고
    • Characteristics of (-)-stepholidine on the firing activity of substantia nigral dopamine neurons after repeated reserpine treatment
    • B.C. Sun, and G.Z. Jin Characteristics of (-)-stepholidine on the firing activity of substantia nigral dopamine neurons after repeated reserpine treatment Biol. Signals 1 1992 331 338
    • (1992) Biol. Signals , vol.1 , pp. 331-338
    • Sun, B.C.1    Jin, G.Z.2
  • 23
    • 0026674825 scopus 로고
    • Effects of (-)-stepholidine on firing activity of dopamine neurons in ventral tegmental area of rats
    • B.C. Sun, and G.Z. Jin Effects of (-)-stepholidine on firing activity of dopamine neurons in ventral tegmental area of rats Zhongguo Yao Li Xue Bao 13 1992 395 399
    • (1992) Zhongguo Yao Li Xue Bao , vol.13 , pp. 395-399
    • Sun, B.C.1    Jin, G.Z.2
  • 25
    • 0035800196 scopus 로고    scopus 로고
    • Estrogen protects against beta-amyloid-induced neurotoxicity in rat hippocampal neurons by activation of Akt
    • L. Zhang, D.R. Rubinow, G. Xaing, B.S. Li, Y.H. Chang, D. Maric, J.L. Barker, and W. Ma Estrogen protects against beta-amyloid-induced neurotoxicity in rat hippocampal neurons by activation of Akt Neuroreport 12 2001 1919 1923
    • (2001) Neuroreport , vol.12 , pp. 1919-1923
    • Zhang, L.1    Rubinow, D.R.2    Xaing, G.3    Li, B.S.4    Chang, Y.H.5    Maric, D.6    Barker, J.L.7    Ma, W.8
  • 26
    • 0032795833 scopus 로고    scopus 로고
    • Action sites of rotation and unit firing induced by l-stepholidine and DA agonists in basal ganglia of 6-OHDA-lesioned rats
    • X.X. Zhang, J. Liu, Y. Fu, G.Y. Hu, and G.Z. Jin Action sites of rotation and unit firing induced by l-stepholidine and DA agonists in basal ganglia of 6-OHDA-lesioned rats Zhongguo Yao Li Xue Bao 20 1999 979 986
    • (1999) Zhongguo Yao Li Xue Bao , vol.20 , pp. 979-986
    • Zhang, X.X.1    Liu, J.2    Fu, Y.3    Hu, G.Y.4    Jin, G.Z.5
  • 27
    • 0032503688 scopus 로고    scopus 로고
    • Comparison of (-)-stepholidine and D1 or D2 agonists on unit firing of globus pallidus in 6-hydroxydopamine-lesioned rats
    • X.X. Zhang, Z.T. Zhu, and G.Z. Jin Comparison of (-)-stepholidine and D1 or D2 agonists on unit firing of globus pallidus in 6-hydroxydopamine-lesioned rats Life Sci. 63 1998 537 544
    • (1998) Life Sci. , vol.63 , pp. 537-544
    • Zhang, X.X.1    Zhu, Z.T.2    Jin, G.Z.3
  • 29
    • 0026365666 scopus 로고
    • Development of natural products as drugs acting on central nervous system
    • X.Z. Zhu Development of natural products as drugs acting on central nervous system Mem. Inst. Oswaldo Cruz 86 Suppl. 2 1991 173 175
    • (1991) Mem. Inst. Oswaldo Cruz , vol.86 , Issue.2 SUPPL. , pp. 173-175
    • Zhu, X.Z.1
  • 30
    • 0346480845 scopus 로고    scopus 로고
    • Electrophysiological study on biphasic firing activity elicited by D(1) agonistic-D(2) antagonistic action of (-)-stepholidine in nucleus accumbens
    • Z.T. Zhu, Y. Fu, G.Y. Hu, and G.Z. Jin Electrophysiological study on biphasic firing activity elicited by D(1) agonistic-D(2) antagonistic action of (-)-stepholidine in nucleus accumbens Sheng Li Xue Bao 52 2000 123 130
    • (2000) Sheng Li Xue Bao , vol.52 , pp. 123-130
    • Zhu, Z.T.1    Fu, Y.2    Hu, G.Y.3    Jin, G.Z.4
  • 31
    • 0034604294 scopus 로고    scopus 로고
    • Modulation of medical prefrontal cortical D1 receptors on the excitatory firing activity of nucleus accumbens neurons elicited by (-)-stepholidine
    • Z.T. Zhu, Y. Fu, G.Y. Hu, and G.Z. Jin Modulation of medical prefrontal cortical D1 receptors on the excitatory firing activity of nucleus accumbens neurons elicited by (-)-stepholidine Life Sci. 67 2000 1265 1274
    • (2000) Life Sci. , vol.67 , pp. 1265-1274
    • Zhu, Z.T.1    Fu, Y.2    Hu, G.Y.3    Jin, G.Z.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.