Morphine sparing with droperidol in patient-controlled analgesia

Journal of Clinical Anesthesia

Volumn 17, Issue 4, 2005, Pages 271-275

  Lo, Yuan ^a   Chia, Yuan Yi ^a,b,c   Liu, Kang ^a,b   Ko, Nai Hua ^a  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NONE   (Taiwan)

Author keywords

Droperidol; Emesis; Morphine: sparing effect of; Patient controlled analgesia

Indexed keywords

DROPERIDOL; MORPHINE;

ABDOMINAL HYSTERECTOMY; ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; EXTRAPYRAMIDAL SYMPTOM; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NAUSEA; PAIN ASSESSMENT; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SEDATION; STATISTICAL SIGNIFICANCE; VOMITING;

ADULT; ANALGESIA, PATIENT-CONTROLLED; DOUBLE-BLIND METHOD; DROPERIDOL; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MIDDLE AGED; MORPHINE; PAIN, POSTOPERATIVE; POSTOPERATIVE NAUSEA AND VOMITING;

EID: 20444407639     PISSN: 09528180     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jclinane.2004.08.010     Document Type: Article

References (18)

1. A. Olschewski, M.E. Brau, G. Hempelmann, W. Vogel, and B.V. Safronov Differential block of fast and slow inactivating tetrodotoxin-sensitive sodium channels by droperidol in spinal dorsal horn neurons Anesthesiology 92 2000 1667 1676
2. E. Gurses, H. Sungurtekin, E. Tomatir, C. Balci, and M. Gonullu The addition of droperidol or clonidine to epidural tramadol shortens onset time and increases duration of postoperative analgesia Can J Anaesth 50 2003 147 152
3. M.R. Tramer, and B. Walder Efficacy and adverse effects of prophylactic antiemetics during patient-controlled analgesia therapy: a quantitative systematic review Anesth Analg 88 1999 1354 1361
4. G.M. Freedman, J.M. Kreitzer, S.S. Reuben, and J.B. Eisenkraft Improving patient-controlled analgesia: adding droperidol to morphine sulfate to reduce nausea and vomiting and potentiate analgesia Mt Sinai J Med 62 1995 221 225
5. S. Yamamoto, H. Yamaguchi, M. Sakaguchi, S. Yamashita, and T. Satsumae Preoperative droperidol improved postoperative pain relief in patients undergoing rotator-cuff repair during general anesthesia using intravenous morphine J Clin Anesth 15 2003 525 529
6. S.K. Sharma, and M.W. Davies Patient-controlled analgesia with a mixture of morphine and droperidol Br J Anaesth 71 1993 435 436
7. O.A. Williams, M. Middleton, P. Henderson, and C.S. Reilly Stability of morphine and droperidol, separately and combined, for use as an infusion Hosp Pharm Pract 2 1992 597 599
8. O.A. Williams, F.L. Clarke, R.W. Harris, P. Smith, and J.E. Peacock Addition of droperidol to patient-controlled analgesia: effect on nausea and vomiting Anaesthesia 48 1993 881 884
9. M. Head, H. Lal, S. Puri, C. Mantione, and D. Valentino Enhancement of morphine analgesia after acute and chronic haloperidol Life Sci 24 1979 2037 2043
10. B. Bissonnette, H. Swan, P. Ravussin, and V. Un Neuroleptanesthesia: current status Can J Anaesth 46 1999 154 168
11. C.C. Chien, and G.W. Pasternak Sigma antagonists potentiate opioid analgesia in rats Neurosci Lett 190 1995 137 139
12. P. Flood, and K.M. Coates Droperidol inhibits GABA(A) and neuronal nicotinic receptor activation Anesthesiology 96 2002 987 993
13. M. Fischler, F. Bonnet, and H. Trang The pharmacokinetics of droperidol in anesthetized patients Anesthesiology 64 1986 486 489
14. E.J. Heyer, and P. Flood Droperidol suppresses spontaneous electrical activity in neurons cultured from ventral midbrain. Implications for neuroleptanesthesia Brain Res 863 2000 20 24
15. P.M. Barrow, D.G. Hughes, N. Redfern, and J. Urie Influence of droperidol on nausea and vomiting during patient-controlled analgesia Br J Anaesth 72 1994 460 461
16. S.M. Yentis, and B. Bissonnette Ineffectiveness of acupuncture and droperidol in preventing vomiting following strabismus repair in children Can J Anaesth 39 1992 151 154
17. A.J. Klahsen, D. O'Reilly, J. McBride, M. Ballantyne, and J.L. Parlow Reduction of post-operative nausea and vomiting with the combination of morphine and droperidol in patient-controlled analgesia Can J Anaesth 43 1996 1100 1107
18. T.J. Gan, P.F. White, P.E. Scuderi, M.F. Watcha, and A. Kovac FDA "black box" warning regarding use of droperidol for postoperative nausea and vomiting: is it justified? Anesthesiology 97 2002 287