Inhibitory action of 5-HT1A agonist MKC-242 on triazolam-induced phase advances in hamster circadian activity rhythms

Journal of Pharmacological Sciences

Volumn 98, Issue 1, 2005, Pages 103-106

  Yokota, Shin Ichi ^a,b   Moriya, Takahiro ^c   Shibata, Shigenobu ^a  

^a WASEDA UNIVERSITY   (Japan)

^b TAISHO PHARMACEUTICAL CO LTD   (Japan)

^c NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

Benzodiazepine; Circadian rhythm; Non photic

Indexed keywords

BENZODIAZEPINE DERIVATIVE; OSEMOZOTAN; SEROTONIN 1A AGONIST; TRIAZOLAM;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DRUG EFFECT; HAMSTER; LOCOMOTION; MALE; MAMMAL; NONHUMAN; PHOTOSTIMULATION; SIGNAL TRANSDUCTION;

EID: 20444405762     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.SC0050058     Document Type: Article

References (13)

1. Inouye ST, Shibata S. Neurochemical organization of circadian rhythms in the suprachiasmatic nucleus. Neurosci Res. 1994; 20:109-130.
2. Hastings MH, Duffield GE, Smith EJ, Maywood ES, Ebling FJ. Entrainment of the circadian system of mammals by nonphotic cues. Chronobiol Int. 1998;15:425-445.
3. Glass JD, Grossman GH, Farnbauch L, DiNardo L. Midbrain raphe modulation of nonphotic circadian clock resetting and 5-HT release in the mammalian suprachiasmatic nucleus. J Neurosci. 2003;23:7451-7460.
4. Morin LP. Serotonin and the regulation of mammalian circadian rhythmicity. Ann Med. 1999;31:12-33.
5. Cutrera RA, Saboureau M, Pevet P. Phase-shifting effect of 8-OH-DPAT, a 5-HT1A/5-HT7 receptor agonist, on locomotor activity in golden hamster in constant darkness. Neurosci Lett. 1996;210:1-4.
6. Meyer-Bernstein EL, Morin LP. Destruction of serotonergic neurons in the median raphe nucleus blocks circadian rhythm phase shifts to triazolam but not to novel wheel access. J Biol Rhythms. 1998;13:494-505.
7. Yokota SI, Horikawa K, Akiyama M, Moriya T, Ebihara S, Komuro G, et al. Inhibitory action of brotizolam on circadian and light-induced per1 and per2 expression in the hamster suprachiasmatic nucleus. Br J Pharmacol. 2000;131:1739-1747.
8. Horikawa K, Yokota S, Fuji K, Akiyama M, Moriya T, Okamura H, et al. Nonphotic entrainment by 5-HT1A/7 receptor agonists accompanied by reduced Per1 and Per2 mRNA levels in the suprachiasmatic nuclei. J Neurosci. 2000;20:5867-5873.
9. Moriya T, Yoshinobu Y, Ikeda M, Yokota S, Akiyama M, Shibata S. Potentiating action of MKC-242, a selective 5-HT1A receptor agonist, on the photic entrainment of the circadian activity rhythm in hamsters. Br J Pharmacol. 1998;125:1281-1287.
10. Takahashi S, Yoshinobu Y, Aida R, Shimomura H, Akiyama M, Moriya T, et al. Extended action of MKC-242, a selective 5-HT(1A) receptor agonist, on light-induced Per gene expression in the suprachiasmatic nucleus in mice. J Neurosci Res. 2002;68:470-478.
11. Daan S, Pittendrigh C. A functional analysis of circadian pacemakers in nocturnal rodents II. The variability of phase response curves. J Comp Physiol A. 1976;106:253-266.
12. Matsuda T, Somboonthum P, Suzuki M, Asano S, Baba A. Antidepressant-like effect by postsynaptic 5-HT1A receptor activation in mice. Eur J Pharmacol. 1995;280:235-238.
13. Lovenberg TW, Baron BM, de Lecea L, Miller JD, Prosser RA, Rea MA, et al. A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms. Neuron. 1993;11:449-458.