Single dose oral clonidine premedication does not enhance postoperative, single low dose epidural morphine analgesia in hysterectomy patients

Journal of the Medical Association of Thailand

Volumn 88, Issue 3, 2005, Pages 358-363

  Oofuvong, Maliwan ^a   Chanvej, Laksamee ^a   Thongsuksai, Paramee ^a  

^a PRINCE OF SONGKLA UNIVERSITY   (Thailand)

Author keywords

Adverse effects; Epidural morphine; Oral clonidine; Postoperative analgesia; Total abdominal hysterectomy

Indexed keywords

ADRENALIN; ATROPINE; CLONIDINE; HALOTHANE; LIDOCAINE; MIDAZOLAM; MORPHINE; NITROUS OXIDE; PARACETAMOL; THIOPENTAL; VECURONIUM;

ANALGESIA; ARTICLE; BRADYCARDIA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG USE; FEMALE; HUMAN; HYPOTENSION; HYSTERECTOMY; LOW DRUG DOSE; NAUSEA; PAIN ASSESSMENT; POSTOPERATIVE ANALGESIA; POSTOPERATIVE CARE; PREMEDICATION; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SEDATION; SINGLE DRUG DOSE; VOMITING;

ADMINISTRATION, ORAL; ADULT; ANALGESICS; ANALGESICS, OPIOID; CLONIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYSTERECTOMY; INJECTIONS, EPIDURAL; MIDDLE AGED; MORPHINE; PREMEDICATION; PROSPECTIVE STUDIES;

EID: 20444401951     PISSN: 01252208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Maze M. Alpha-2 adrenoreceptor agonists: defining the role in clinical anesthesia. Anesthesiology 1991; 74: 581-605.
2. Hayashi Y. Alpha-2 adrenoceptor agonists and anesthesia. Br J Anaesth 1993; 71: 108-18.
3. Eisenach JC. Alpha-2 adrenergic agonist for regional anesthesia: a clinical review of clonidine (1984-1995). Anesthesiology 1996; 85: 655-74.
4. Bernard JM, Hommeril JL, Passuti N, Pinaud M. Postoperative analgesia by intravenous clonidine. Anesthesiology 1991; 75: 577-82.
5. De Kock MF, Pichon G, Scholtes JL. Intraoperative clonidine enhances postoperative morphine patient-controlled analgesia. Can J Anaesth 1992; 39: 537-44.
6. Filos KS, Goudas LC, Patroni O, Polyzou V. Intrathecal clonidine as a sole analgesic for pain relief after cesarean section. Anesthesiology 1992; 77: 267-74.
7. Grace D, Bunting H, Milligan KR, Fee JP. Post-operative analgesia after co-administration of clonidine and morphine by the intrathecal route in patients undergoing hip replacement. Anesth Analg 1995; 80: 86-91.
8. Anzai Y, Nishikawa T. Thoracic epidural clonidine and morphine for postoperative pain relief. Can J Anaesth 1995; 42: 292-7.
9. De Kock M, Gautier P, Pavlopoulou A, Jonniaux M, Lavan d'homme P. Epidural clonidine or bupivacaine as the sole analgesic agent during and after abdominal surgery: a comparative study. Anesthesiology 1999; 90: 1354-62.
10. Filos KS, Goudas LC, Patroni O, Polyzou V. Hemodynamic and analgesic profile after intrathecal clonidine in humans. A dose-response study. Anesthesiology 1994; 81: 591-601.
11. Ota K, Namiki A, Iwasaki H, Takahashi I. Dose-related prolongation of tetracaine spinal anesthesia by oral clonidine in humans. Anesth Analg 1994; 79: 1121-5.
12. Singh H, Liu J, Gaines GY, White PF. Effect of oral clonidine and intrathecal fentanyl on tetracaine spinal block. Anesth Analg 1994; 79: 1113-6.
13. Mayson KV, Gofton EA, Chambers KG. Premedication with low dose oral clonidine does not enhance postoperative analgesia of intrathecal morphine. Can J Anaesth 2000; 47: 752-7.
14. Ezri T, Szmuk P, Shklar B, Katz J, Geva D. Oral clonidine premedication does not prolong analgesia after herniorrhaphy under subarachnoid anesthesia. J Clin Anesth 1998; 10: 474-81.
15. Goyagi T, Nishikawa T. Oral clonidine premedication enhances the quality of postoperative analgesia by intrathecal morphine. Anesth Analg 1996; 82: 1192-6.
16. Goyagi T, Tanaka M, Nishikawa T. Oral clonidine premedication enhances postoperative analgesia by epidural morphine. Anesth Analg 1999; 89: 1487-91.
17. Tonner PH. Alpha-2 adrenoceptor agonists in anesthesia. Refresher Course in European society of Anaesthesiologists. [serial on the internet], 2003 May [cited 2004 Sep 6]:[7 pages]. Available from: http://www.euroanesthesia.org/_education/rc2003glasgow/EAArcl.pdf.
18. Benhamou D, Narchi P, Hamza J, Marx M, Peyrol MT, Sembeil F. Addition of oral clonidine to postoperative patient-controlled analgesia with i.v. morphine. Br J Anaesth 1994; 72: 537-40.
19. Park J, Forrest J, Kolesar R, Bhola D, Beattie S, Chu C. Oral clonidine reduces postoperative PCA morphine requirements. Can J Anaesth 1996; 43: 900-6.
20. Segal IS, Jarvis DJ, Duncan SR, White PF, Maze M. Clinical efficacy of oral-transdermal clonidine combinations during the perioperative period. Anesthesiology 1991; 74: 220-5.
21. Stuhmeier K-D, Mainzer B, Cierpka J, Sandmann W, Tarnow J. Small, oral dose of clonidine reduces the incidence of intraoperative myocardial ischemia in patients having vascular surgery. Anesthesiology 1996; 85: 706-12.
22. Schug SA, Sidebotham DA, McGuinnety M, Thomas J, Fox L. Acetaminophen as an adjunct to morphine by patient-controlled analgesia in the management of acute postoperative pain. Anesth Analg 1998; 87: 368-72.
23. Ramer L, Richardson JL, Cohen MZ, Bedney C, Danley KL, Judge EA. Multimeasure pain assessment in an ethnically diverse group of patients with cancer. J Transcult Nurs 1999; 10: 94-101.