Synthesis and biological activity profile of new analogues of the cyclic opioid peptide H-Tyr-C(D-Cys-Gly-Phe(pNO2)-D-Cys)-NH2 containing (S)-α-hydroxymethylcysteine in place of cysteine

Journal of Peptide Science

Volumn 11, Issue 6, 2005, Pages 361-363

  Witkowska, Renata ^a   Chung, Nga N ^b   Schiller, Peter W ^b   Zabrocki, Janusz ^a  

^a LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

hydroxymethylamino acids; hydroxymethylcysteine; Opioid activity; Opioid peptides

Indexed keywords

HYDROXYTYROSINE ALPHA HYDROXYMETHYLCYSTEINYLGLYCINE 4 NITROPHENYLALANINE ALPHA HYDROXYMETHYLCYSTEINAMIDE; HYDROXYTYROSINE ALPHA HYDROXYMETHYLCYSTEINYLGLYCINE 4 NITROPHENYLALANINE DEXTRO CYSTEINAMIDE; HYDROXYTYROSINE DEXTRO CYSTEINYLGLYCINE 4 NITROPHENYLALANINE ALPHA HYDROXYMETHYCYSTEINAMIDE; HYDROXYTYROSYLCYCLO(ALPHA HYDROXYMETHYLCYSTEINYLGLYCINE 4 NITROPHENYLALANINE DEXTRO CYSTEINAMIDE); HYDROXYTYROSYLCYCLO(DEXTRO CYSTEINYLGLYCINE 4 NITROPHENYLALANINE ALPHA HYDROXYMETHYLCYSTEINAMIDE); HYDROXYTYROSYLCYCLO(HYDROXYMETHYLCYSTEINYLGLYCINE 4 NITROPHENYLALANINE ALPHA HYDROXYMETHYLCYSTEINAMIDE); KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; OPIATE PEPTIDE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; GUINEA PIG; ILEUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; VAS DEFERENS;

AMINO ACID SEQUENCE; CYSTEINE; MOLECULAR WEIGHT; OPIOID PEPTIDES; PEPTIDES, CYCLIC; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 20444387227     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/psc.620     Document Type: Article

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