Novel effects of gefitinib on mucin production in bronchioloalveolar carcinoma; two case reports

Lung Cancer

Volumn 49, Issue 1, 2005, Pages 125-128

  Kitazaki, Takeshi ^a,b   Fukuda, Masaaki ^a   Soda, Hiroshi ^b   Kohno, Shigeru ^b  

^a JAPANESE RED CROSS SOCIETY   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

Bronchorrhea; Epidermal growth factor; Gefitinib; Hypoxemia; Lung cancer; Molecular targeted therapy

Indexed keywords

CARBOPLATIN; DOCETAXEL; GEFITINIB; IRINOTECAN; MUCIN; NAVELBINE;

ADULT; AGED; ARTICLE; BRONCHORRHEA; COMPUTER ASSISTED TOMOGRAPHY; DYSPNEA; FEMALE; HOSPITAL ADMISSION; HUMAN; LUNG ALVEOLUS CELL CARCINOMA; LUNG BIOPSY; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; THORAX RADIOGRAPHY; TRANSBRONCHIAL BIOPSY;

ADENOCARCINOMA, BRONCHIOLO-ALVEOLAR; AGED; ANTINEOPLASTIC AGENTS; DYSPNEA; FEMALE; HUMANS; LUNG NEOPLASMS; MUCINS; QUINAZOLINES;

EID: 20444362403     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2004.11.027     Document Type: Article

References (14)

1. J.E. Barkley, and M.R. Green Bronchioloalveolar carcinoma J Clin Oncol 14 1996 2377 2386
2. D.R. Gandara, H. West, K. Chansky, A.M. Davies, D.H.M. Lau, and J. Crowley Bronchioloalveolar carcinoma: a model for investigating the biology of epidermal growth factor receptor inhibition Clin Cancer Res 10 2004 4205 4209
3. J.G. Paez, P.A. Janne, J.C. Lee, S. Tracy, H. Greulich, and S. Gabriel EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy Science 304 2004 1497 1500
4. W.A. Franklin, K. Chansky, H. West, P.H. Gumerlock, F.R. Hirsch, and D.R. Gandara Association between activation of ErbB pathway genes and survival following gefitinib treatment in advanced BAC (SWOG 0126) Proc Am Soc Clin Oncol 22 2004 7015
5. V.A. Miller, M.G. Kris, N. Shah, J. Patel, C. Azzoli, and J. Gomez Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer J Clin Oncol 22 2004 1103 1109
6. V.A. Miller, J. Patel, N. Shah, M.G. Kris, L. Tyson, and B. Pizzo The epidermal growth factor receptor tyrosine kinase inhibitor erlotinib (OSI-774) shows promising activity inpatients with bronchioloalveolar cell carcinoma (BAC): preliminary results of a phase II trial Proc Am Soc Clin Oncol 22 2003 619 [abstract 2491]
7. H. Degrandele Epidermal growth factor receptor inhibitors, gefitinib and erlotinib (Tarceva, OSI-774), in the treatment of bronchioloalveolar carcinoma Clin Lung Cancer 5 2003 83 85
8. S. Yano, T. Kanematsu, T. Miki, Y. Aono, M. Azuma, and A. Yamamoto A report of two bronchioloalveolar carcinoma cases which were rapidly improved by treatment with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 ("Iressa") Cancer Sci 94 2003 453 458
9. M. Takao, K. Inoue, F. Watanabe, K. Onoda, T. Shimono, and H. Shimpo Successful treatment of persistent bronchorrhea by gefitinib in a case with recurrent bronchioloalveolar carcinoma: a case report World J Surg Oncol 1 2003 1
10. K. Fujiwara, K. Kiura, H. Ueoka, M. Tabata, S. Hamasaki, and M. Tanimoto Dramatic effect of ZD1839 ('Iressa') in a patient with advanced non-small cell lung cancer and poor performance status Lung Cancer 40 2003 73 76
11. R.B. Natale Epidermal growth factor receptor-targeted therapy with ZD1839: symptom improvement in non-small-call lung cancer Int J Radiat Oncol Biol Phys 59 2004 39 43
12. K. Takeyama, K. Dabbagh, H.M. Lee, C. Agusti, J.A. Lausier, and I.F. Ueki Epidermal growth factor system regulates mucin production in airways Proc Natl Acad Sci USA 96 1999 3081 3086
13. M. Perrais, P. Pigny, M.C. Copin, J.P. Aubert, and I. Van Seuningen Induction of MUC2 and MUC5AC mucins by factors of the epidermal growth factor (EGF) family is mediated by EGF receptor/Ras/Raf/extracelllular signal-regulated kinase cascade and Sp1 J Biol Chem 277 2002 32258 32267
14. J.T. Berger, J.A. Voynow, K.W. Peters, and M.C. Rose Respiratory carcinoima cell lines Am J Respir Cell Mol Biol 20 1999 500 510