Optimization of nicotine extraction from tobacco using supercritical fluid technology with dynamic extraction modeling

Journal of Agricultural and Food Chemistry

Volumn 44, Issue 5, 1996, Pages 1258-1264

  Fischer, Monika ^a   Jefferies, Terry M ^a  

^a University of Bath   (United Kingdom)

Author keywords

Supercritical fluid extraction (SFE); Tobacco, nicotine

Indexed keywords

NICOTIANA TABACUM;

EID: 2042528909     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf950502+     Document Type: Article

References (14)

1. Bartle, K. D.; Clifford, A. A.; Hawthorne, S. B.; Langenfeld, J. J.; Miller, D. J.; Robinson, R. A model for dynamic extraction using a supercritical fluid. J. Supercrit. Fluids 1990, 3, 143-149.
2. Bartle, K. D.; Boddington, T.; Clifford, A. A.; Hawthorne, S. B. The effect of solubility on the kinetics of dynamic supercritical-fluid extraction. J. Supercrit. Fluids 1992, 5, 207-212.
3. Cotton, N. J.; Bartle, K. D.; Clifford, A. A.; Dowle, C. J. Rate and extent of supercritical fluid extraction of additives from polypropylene: diffusion, solubility, and matrix effects. J. Appl. Polym. Sci. 1993, 48, 1607-1619.
4. Fischer, M.; Jefferies, T. M. Optimization of supercritical fluid conditions for the rapid determination of free fatty acids in soy and cottonseed meals. J. Agric. Food Chem. 1995, 43 (5), 1259-1266.
5. Hawthorne, S. B.; Miller, D. J.; Burford, M. D.; Langenfeld, J. J.; Eckert-Tilotta, S.; Louie, P. K. Factors controlling quantitative supercritical fluid extraction of environmental samples. J. Chromatogr. 1993, 642, 301-317.
6. Kleiner, K. US ruling turns smokers into junkies. New Sci. 1994, 143, 1938, 10.
7. MacKenzie, D. Transgenic tobacco is European first. New Sci. 1994, 142, 1930, 8.
8. Pawliszyn, J. Kinetic model of supercritical fluid extraction. J. Chromatogr. Sci. 1993, 31, 31-37.
9. Roselius, W.; Vitzhum, O.; Hubert, P. Process for the extraction of nicotine from tobacco. U.S. Patent 4,153,063, 1979.
10. Saunders, J. A.; Blume, D. E. Quantitation of major tobacco alkaloids by high-performance liquid chromatography. J. Chromatogr. 1981, 205, 147-154.
11. Severson, R. F.; McDuffie, K. L.; Arrendale, R. F.; Gwynn, G. R.; Chaplin, J. F.; Johnson, A. W. Rapid method for the analysis of tobacco nicotine alkaloids. J. Chromatogr. 1981, 211, 111-121.
12. Sharma, A. K.; Prokopczyk, B.; Hoffmann, D. Supercritical fluid extraction of moist snuff. J. Agric. Food Chem. 1991, 39 (3), 508-510.
13. Sudan, B. J. L.; Brouillard, C.; Strehler, C.; Strub, H.; Sterboul, J.; Sainte-Laudy, J. Determination of nicotine in allergenic extracts of tobacco leaf by high-performance liquid chromatography. J. Chromatogr. 1984, 288, 415-422.
14. Zuccaro, P.; Altieri, I.; Rosa, M.; Passa, A. R.; Pichini, S.; Ricciarello, G.; Pacifici, R. Determination of nicotine and four metabolites in the serum of smokers by high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. 1993, 621, 257-261.