In vitro susceptibility study of herpes simplex virus to acyclovir and foscarnet. Are routine susceptibility studies necessary?;Estudio de sensibilidad in vitro del virus herpes simple a aciclovir y foscarnet. ¿Son necesarios los estudios de sensibilidad de forma rutinaria?

Enfermedades Infecciosas y Microbiologia Clinica

Volumn 20, Issue 1, 2002, Pages 25-27

  Losada, Isabel ^a   Cañizares, Ángeles ^a   Hellín, Teresa ^b   Martí Belda, Paloma ^b   Guerrero, Antonio ^c  

^a HOSPITAL JUAN CANALEJO   (Spain)

^b HOSPITAL RAMÓN Y CAJAL   (Spain)

^c HOSPITAL DE LA RIBERA   (Spain)

Author keywords

Acyclovir; Foscarnet; Herpes simplex virus; Resistance

Indexed keywords

ACICLOVIR; FOSCARNET;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG SENSITIVITY; HERPES SIMPLEX VIRUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; NONHUMAN; SCREENING TEST; VIRUS RESISTANCE; VIRUS STRAIN;

EID: 2042513576     PISSN: 0213005X     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0213-005x(02)72727-4     Document Type: Article

References (11)

1. Englund JA, Zimmerman ME, Swierkosz EM, Goodman JL, Scholl DR, Balfour HH. Herpes simplex resistant to acyclovir. Ann Intern Med 1990;112: 416-22.
2. Gimeno C. Virus herpes simplex resistentes a drogas antivirales: incidencia y significación clínica en pacientes inmunocomprometidos. [Tesis doctoral]. Madrid: Facultad de Medicina, Universidad Complutense, 1996.
3. Cotarelo M. Virus herpes simplex: estudio de sensibilidad in vitro frente a antivirales en un hospital general. [Tesis doctoral.] Madrid: Facultad de Farmacia, Universidad Complutense, 1997.
4. Safrin S, Kemmerly S, Plotkin B, Smith T, Weissbach N, Veranez D, et al. Foscarnet-resistant herpes simplex virus infection in patients with AIDS. J Infect Dis 1994;169:193-6.
5. Safrin S, Elbeik T, Phan L, Robinson D, Rush J, Elbaggari A, et al. Correlation between response to acyclovir and foscarnet therapy in vitro susceptibility result for isolates of herpes simplex virus from human immunodeficiency virus infected patients. Antimicrob Agents Chemother 1994;38: 1246-50.
6. Safrin S, Elbeik T, Mills J. Rapid screen test for in vitro susceptibility of clinical herpes simplex virus isolates. J Infect Dis 1994;169:879-82.
7. Tebas P, Scholl D, Jollick J, McHarg K, Arens M, Olivo PD. A rapid assay to screen for drug-resistant herpes simplex virus. J Infect Dis 1998;177: 217-20.
8. Antiviral Susceptibility Testing. Clinical Microbiology Procedures Handbook. Isenberg: American Society for Microbiology, 1992.
9. Safrin S, Elbeik T, Phan L, Robinson D, Rush J, Elbaggari A, et al. Correlation between response to acyclovir and foscarnet therapy and in vitro susceptibility result for isolates of herpes simplex virus from human immunodeficiency virus-infected patients. Antimicrob Agents Chemother 1994;38: 1246-50.
10. Snoeck R. Antiviral therapy of herpes simplex. Int J Antimicrob Agents 2000;16:157-9.
11. Reusser P. Herpesvirus resistance to antiviral drugs: a review of the mechanisms, clinical importance and therapeutic options. J Hosp Infect 1996; 33:235-48.