Random outcomes of allergen-specific responses in atopic families

Clinical and Experimental Allergy

Volumn 34, Issue 4, 2004, Pages 540-547

  Jackola, D R ^a   Liebeler, C L ^a   Blumenthal, M N ^a   Rosenberg, A ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Allergen; Atopy; Skin prick test

Indexed keywords

ALLERGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN A2; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4;

ARTICLE; ATOPY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE PREDISPOSITION; ENVIRONMENTAL EXPOSURE; FAMILIAL DISEASE; FEMALE; HUMAN; INHERITANCE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RANDOMIZATION; SKIN TEST; STANDARDIZATION;

ADULT; ALLERGENS; CHILD; ENVIRONMENTAL EXPOSURE; EPITOPES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; SKIN TESTS; STOCHASTIC PROCESSES;

EID: 2042472810     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2004.1920.x     Document Type: Article

References (31)

1. Jackola DR, Pierson-Mullany LK, Liebeler CL, Blumenthal MN, Rosenberg A. Variable binding affinities for allergen suggest a 'selective competition' among immunoglobulins in atopic and non- atopic humans. Molec Immunol 2002; 39:367-77.
2. Allauzen S, Blocki F, Pierson-Mullany L et al. Expression of IgH chain genes in antibody response to ragweed and purified Amb a 1: evidence for differential regulation of isotype production. Molec Immunol 1999; 36:587-98.
3. Batard T, Basuyuax B, Lambin P, Brémard-Oury C, Hamilton RG, Peltre G. Isotype analysis of grass pollen-specific immunoglobulins in human plasma. I. Specialization of certain classes and subclasses in the immune response. Int Arch Allergy Immunol 1993; 100:68-78.
4. Batard T, Basuyuaux B, Laroze A et al. Isotype analysis of grass pollen-specific immunoglobulins in human plasma. II. Quantification of the IgE, IgM, IgA class and the IgG subclass antibodies. Int Arch Allergy Immunol 1993; 102:279-87.
5. Blumenthal MN, Björkstén B., (eds.). Genetics of Allergy and Asthma. New York: Marcel Dekker, Inc., 1997.
6. Marsh DG. Allergens and allergen nomenclature. In: Marsh DG, Blumenthal MN, eds. Genetic and Environmental Factors In Clinical Allergy. Minneapolis: University of Minnesota Press, 1990; 20-31.
7. Blumenthal MN, Rosenberg A. Definition of an allergen (immunobiology). In: Lockey RF, Bukantz SC, eds. Allergens and Allergen Immunotherapy. New York: Marcel Dekker, Inc., 1999; 39-51.
8. Wabl M, Steinberg C. Affinity maturation and class switching. Curr Opin Immunol 1996; 8:89-92.
9. Sebzda E, Mariathasan S, Ohteki T, Jones R, Bachmann MF, Ohashi PS. Selection of the T cell repertoire. Ann Rev Immunol 1999; 17:829-74.
10. Rudolph MG, Wilson IA. The specificity of TCR/pMHC interaction. Curr Opin Immunol 2002; 14:52-65.
11. Rhodes DA, Trowsdale J. Genetics and molecular genetics of the MHC. Rev Immunogenetics 1999; 1:21-31.
12. Moffat MF, Cookson WOCM. The genetics of specific allergy. In: Hall IP, ed. Genetics of Asthma and Atopy. Basel: Karger. Mongr Allergy 1996; 33:71-96.
13. ISAAC (International Study of Asthma and Allergies in Childhood Steering Committee). Worldwide variations in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis and atopic eczema. Lancet 1998; 351:1225-32.
14. Hanson B, McGue M, Roitman-Johnson B, Bouchardt TJ Jr., Blumenthal MN. Atopic disease and immunoglobulin E in twins reared apart and together. Am J Human Genet 1991; 48:873-9.
15. Schultz-Larsen F. A genetic-epidemiological study in a population- based twin sample. J Am Acad Dermatol 1993; 28:719-23.
16. Jones CA, Kilburn SA, Warner JA, Warner JO. Intrauterine environment and fetal sensitization. Clin Exp Allergy 1998; 28:655-9.
17. Marsh DG. Approaches toward the genetic analysis of complex traits: asthma and atopy. Allergy 1999; 54:198-205.
18. De Swert LFA. Risk factors for allergy. Eur J Pediatr 1999; 158:89-94.
19. CSGA (Collaborative Study on the Genetics of Asthma). A genome-wide search for asthma susceptibility loci in ethnically diverse populations. Nat Genet 1997; 15:389-92.
20. American Thoracic Society. Standardization of spirometry - 1987 update. Am J Respir Crit Care Med 1987; 153:1285-98.
21. Keeping ES. Introduction to Statistical Inference. New York: Dover Publications, Inc, 1995; 308-14.
22. Feller W. Chapter V. Conditional probability. Stochastic independence. In: An Introduction To probability Theory and its Applications, Vol. I. New York: John Wiley & Sons, Inc., 1968; 114-45.
23. Barbee RA, Halonen M, Lebowitz M, Burrows B. Distribution of IgE in a community population sample: correlations with age, sex, and allergen skin test reactivity. J Allergy Clin Immunol 1981; 68:106-11.
24. Sutton BJ, Gould HJ. The human IgE network. Nature 1993; 366:421-8.
25. Snow RE, Djukanovic R, Stevenson FK. Analysis of immunoglobulin E VH transcripts in a bronchial biopsy of an asthmatic patient confirms bias toward VH5, and indicates local clonal expansion, somatic mutation and isotype switch. Immunology 1999; 98:646-51.
26. Aalberse RC. Specific IgE and IgG responses in atopic versus nonatopic subjects. Am J Respir Crit Care Med 2000; 162:8124-7.
27. Marsh DG, Rafnan T, Ghosh B, Huang S-K. Specific immune responses to purified allergen. In: Blumenthal MN, Björkstén B, eds. Genetics of Allergy and Asthma. New York: Marcel Dekker, Inc., 1997; 197-210.
28. Marsh DG, Bias WB, Ishizaka K. Genetic control of basal serum immunoglobulin E and its effect on specific reaginic sensitivity. Proc Natl Acad Sci USA 1974; 71:3588-92.
29. Jackola DR, Pierson-Mullany L, Blumenthal MN, Rosenberg A. Allergen skin test reaction patterns in children (≤ 10 y.o.) from atopic families suggest age-dependent changes in allergen-IgE binding in early life. Int Arch Allergy Immunol 2003; 132:364-72.
30. Germain RN. The art of the probable: system control in the adaptive immune system. Science 2001; 293:240-5.
31. Matzinger P. Tolerance, danger and the extended family. Ann Rev Immunol 1994; 12:991-1045.