Reactivated fulminant hepatitis B virus replication after bone marrow transplantation: Clinical course and possible treatment with ganciclovir

Journal of Hepatology

Volumn 25, Issue 6, 1996, Pages 968-971

  Mertens, Thomas ^b   Köck, Josef ^c   Hampl, Walter ^c   Schlicht, Hans Jürgen ^c   Tillmann, Hans L ^a   Oldhafer, Karl Jürgen ^a   Manns, Michael P ^a   Arnold, Renate ^c  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF ULM   (Germany)

^c NONE

Author keywords

Bone marrow transplantation; Fulminant hepatitis B; Immunosuppression; Therapy

Indexed keywords

ACICLOVIR; GANCICLOVIR; IMMUNOGLOBULIN G; VIRUS DNA;

ADULT; ARTICLE; BONE MARROW TRANSPLANTATION; CASE REPORT; CLINICAL TRIAL; FEMALE; HEPATITIS B; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LIVER FAILURE; PRIORITY JOURNAL; VIRUS HEPATITIS; VIRUS REPLICATION;

EID: 2042455110     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(96)80303-5     Document Type: Article

References (14)

1. 1. Pariente EA, Goudeau A, Dubois F, Degott C, Gluckman E, Devergie A, Brechot C, Schenmetzler C, Bernuau-J. Fulminant hepatitis due to reactivation of chronic hepatitis B virus infection after allogeneic bone marrow transplantation. Dig Dis Sci 1988; 33: 1185-91.
2. 2. Webster A, Brenner MK, Prentice HG, Griffiths PD. Fatal hepatitis B reactivation after autologous bone marrow transplantation. Bone Marrow Transplant 1989; 4: 207-8.
3. 3. McIvor C, Morton J, Bryant A, Cooksley WG, Durant S, Walker N. Fatal reactivation of precore mutant hepatitis B virus associated with fibrosing cholestatic hepatitis after bone-marrow transplantation. Ann Intern Med 1994; 121: 274-5.
4. 4. Martin BA, Rowe JM, Kouides PA, DiPersio JF. Hepatitis B reactivation following allogeneic bone marrow transplantation: case report and review of the literature. Bone Marrow Transplant 1995; 15: 145-8.
5. 5. Reed EC, Myerson D, Corey L, Meyers JD. Allogeneic marrow transplantation in patients positive for hepatitis B surface antigen. Blood 1991; 77: 195-200.
6. 6. Locasciulli A, Alberti A, De Bock R, Cordonnier C, Einsele H, Engelhard D, Grundy J, Reusser P, Ribaud P, Ljungman P. Impact of liver disease and hepatitis infections on allogeneic bone marrow transplantation in Europe: a survey from the European Bone Marrow Transplantation (EBMT) Group-Infectious Diseases Working Party. Bone Marrow Transplant 1994; 14: 833-7.
7. 7. Ilan Y, Nagler A, Adler R, Naparstek E, Or R, Slavin S, Brautbar C, Shouval D. Adoptive transfer of immunity to hepatitis B virus after T cell-depleted allogeneic bone marrow transplantation. Hepatology 1993; 18: 246-52.
8. 8. Ilan Y, Nagler A, Adler R, Tur-Kaspa R, Slavin S, Shouval D. Ablation of persistent hepatitis B by bone marrow transplantation from a hepatitis B-immune donor. Gastroenterology 1993; 104: 1818-21.
9. 9. Locasciulli A, Bacigalupo A, Van Lint MT, Chemello L, Pontisso P, Occhini D, Uderzo C, Shulman HM, Portmann B, Marmont AM, Alberti A. Hepatitis B virus (HBV) infection and liver disease after allogeneic bone marrow transplantation: a report of 30 cases. Bone Marrow Transplant 1990; 6: 25-9.
10. 10. Arnold R, Bunjes D, Wiesneth M, Hertenstein B, Theobald M, Heimpel H, Hale G, Waldmann H. In vitro and in vivo depletion of T-cells. Bone Marrow Transplant 1993; 12 Suppl. 3: 11-2.
11. 11. Hertenstein B, Hampl W, Bunjes D, Wiesneth M, Duncker C, Koszinowski U, Heimpel H, Arnold R, Mertens T. In vivo/ex vivo T cell depletion for GVHD prophylaxis influences onset and course of active cytomegalovirus infection and disease after BMT. Bone Marrow Transplant 1995; 15: 387-93.
12. 12. Angus P, Richards M, Bowden S, Ireton J, Sinclair R, Jones R, Locarnini S. Combination antiviral therapy controls severe post-liver transplant recurrence of hepatitis B virus infection. J Gastroenterol Hepatol 1993; 8: 353-7.
13. 13. Wang Y, Luscombe C, Bowden S, Shaw T, Locarnini S. Inhibition of duck hepatitis B virus DNA replication by antiviral chemotherapy with ganciclovir-nalidixic acid. Antimicrob Agents Chemother 1995; 39: 556-8.
14. 14. Dienstag JL, Perrillo RP, Schiff ER, Bartholomew M, Vicary C, Rubin M. A preliminary trial of lamivudine for chronic hepatitis B infection. N Engl J Med 1995; 333: 1657-61.