Oxycodone pharmacokinetics and pharmacodynamics in the rat in the presence of the P-glycoprotein inhibitor PSC833

Journal of Pharmaceutical Sciences

Volumn 94, Issue 5, 2005, Pages 1060-1066

  Boström, Emma ^a   Simonsson, Ulrika S H ^a   Hammarlund Udenaes, Margareta ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Active transports; Blood brain barrier; Clearance; CNS; Efflux pumps; P glycoprotein; Pharmacokinetics pharmacodynamics; Transporters

Indexed keywords

GLYCOPROTEIN P; GLYCOPROTEIN P INHIBITOR; OXYCODONE; VALSPODAR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG INFUSION; MALE; NONHUMAN; PHARMACODYNAMICS; PLASMA CLEARANCE; RAT; TAIL FLICK TEST;

EID: 20344398703     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.20327     Document Type: Article

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