Letter to the editor

Journal of Pharmaceutical Sciences

Volumn 94, Issue 5, 2005, Pages 946-947

  Nagilla, Rakesh ^a   Ward, Keith W ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CEFODIZIME; DOXORUBICIN; VINBLASTINE;

DOG; DRUG CLEARANCE; DRUG INDUSTRY; GOAT; GUINEA PIG; LETTER; LIVER BLOOD FLOW; MONKEY; NONHUMAN; RAT; SHEEP; SWINE;

EID: 20344394422     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.20300     Document Type: Letter

References (9)

1. Nagilla R, Ward KW. 2004. A comprehensive analysis of the role of correction factors in the allometric predictivity of clearance from rat, dog, and monkey to human. J Pharm Sci 93:2522-2534 (2004)
2. published erratum, J Pharm Sci 94:231-232, 2005
3. Ward KW, Smith BR. 2004. A comprehensive quantitative and qualitative evaluation of extrapolation of intravenous pharmacokinetic parameters from rat, dog, and monkey to humans. I. Clearance. Drug Metab Dispos 32:603-611.
4. Mahmood I, Balian JD. 1996. Interspecies scaling: Predicting clearance of drugs in humans. Three different approaches. Xenobiotica 26:887-895.
5. Mahmood I. 1998. Interspecies scaling of renally secreted drugs. Life Sci 63:2365-2371.
6. Jolivette LJ, Ward KW. 2004. Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. J Pharm Sci (submitted).
7. Wilkinson GR. 1987. Clearance approaches in pharmacology. Pharm Rev 39:1-47.
8. Nagilla R, Ward KW. Identification and characterization of xenobiotics for which the rule of exponents affords less accurate human clearance predictivity than simple allometry. In preparation.
9. Bonate PL, Howard D. 2000. Critique of prospective allometric scaling: Does the emperor have clothes? J Clin Pharmacol 40:335-340.