A method to monitor local changes in MR signal intensity in articular cartilage: A potential marker for cartilage degeneration in osteoarthritis

Lecture Notes in Computer Science

Volumn 3217, Issue 1 PART 2, 2004, Pages 959-966

  Naish, Josephine H ^a   Vincent, Graham ^b   Bowes, Mike ^b   Kothari, Manish ^c   White, David ^c   Waterton, John C ^d   Taylor, Chris J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b IMORPHICS LTD   (United Kingdom)

^c SYNARC INC   (United States)

^d ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; HYDRATION; IMAGE PROCESSING; JOINTS (ANATOMY); MAGNETIC RESONANCE IMAGING; MEDICAL IMAGING; PATIENT TREATMENT; VISUALIZATION; MEDICAL COMPUTING;

ACTIVE APPEARANCE MODEL (AAM); DISEASE PROGRESSION; ECHO MAGNETIC RESONANCE; OSTEOARTHRITIS (OA); 3D GRADIENTS; ACTIVE APPEARANCE MODELS; ARTICULAR CARTILAGES; CARTILAGE VOLUME; COMPOSITIONAL INTEGRITY; MR IMAGES; MR SIGNALS; SIGNAL INTENSITIES;

CARTILAGE;

EID: 20344386226     PISSN: 03029743     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1007/978-3-540-30136-3_116     Document Type: Conference Paper

References (11)

1. Peterfy CG, van Dijke CF, Janzen DL, Gluer CC, Namba R, Majumdar S, Lang P, and Genant HK. Quantification of articular cartilage in the knee with pulsed saturation transfer subtraction and fat-suppressed mr imaging: optimization and validation. Radiology, 192(2):485-91, 1994.
2. Gandy SJ, Dieppe PA, Keen MC, Maciewicz RA, Watt I, and Waterton JC. No loss of cartilage volume over three years in patients with knee osteoarthritis as assessed by magnetic resonance imaging. Osteoarthritis Cartilage, 10(12):929-37, 2002.
3. Lüsse S, Claassen H, Gehrke T, Hassenpflug J, Schunke M, Heller M, and Gluer CC. Evaluation of water content by spatially resolved transverse relaxation times of human articular cartilage. Magn Reson Imaging, 18(4):423-30, 2000.
4. Selby K, Peterfy CG, Cohen ZA, Ateshian GA, Mow VC, Roos M, Wong S, Newitt DC, van Dijke CJ, Wendland M, and Genant HK. In vivo MR quantification of articular cartilage water content: a potential early indicator of arthritis. Proc Intl Soc Magn Reson Med, 3:204, 1995.
5. Gillis A, Gray M, and Burstein D. Relaxivity and diffusion of gadolinium agents in cartilage. Magn Reson Med, 48(6):1068-71, 2002.
6. Shapiro EM, Borthakur A, Gougoutas A, and Reddy R. 23Na MRI accurately measures fixed charge density in articular cartilage. Magn Reson Med, 47(2):284-91, 2002.
7. Kim DK, Ceckler TL, Hascall VC, Calabro A, and Balaban RS. Analysis of watermacromolecule proton magnetization transfer in articular cartilage. Magn Reson Med, 29(2):211-5, 1993.
8. Smith HE, Mosher TJ, Dardzinski BJ, Collins BG, Collins CM, Yang QX, Schmithorst VJ, and Smith MB. Spatial variation in cartilage T2 of the knee. J Magn Reson Imaging, 14(1):50-5, 2001.
9. Liess C, Lusse S, Karger N, Heller M, and Gluer CC. Detection of changes in cartilage water content using MRI T2-mapping in vivo. Osteoarthritis Cartilage, 10(12):907-13, 2002.
10. Williams TG, Taylor CJ, Gao ZX, and Waterton JC. Corresponding articular cartilage thickness measurements in the knee joint by modelling the underlying bone. Lect Notes Comput Sc, 2732:126-135, 2003.
11. Cootes TF, Edwards GJ, and Taylor CJ. Active Appearance Models. IEEE Transactions on Pattern Analysis and Machine Intelligence, 23(6):681-685, 2001.