Challenges in the diagnosis and management of neonatal herpes simplex virus encephalitis

Pediatrics

Volumn 115, Issue 3, 2005, Pages 795-797

  Frenkel, Lisa M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; PRODRUG; VIRUS DNA; ANTIVIRUS AGENT;

CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID EXAMINATION; CLINICAL EXAMINATION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG EFFICACY; DRUG SAFETY; EARLY DIAGNOSIS; EYE INFECTION; HERPES SIMPLEX VIRUS; HUMAN; LEUKOCYTE; LONG TERM CARE; MOUTH INFECTION; NEUTROPENIA; NEUTROPHIL; NEWBORN INFECTION; NONHUMAN; NOTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RECURRENT INFECTION; SKIN INFECTION; SYMPTOMATOLOGY; SYNDROME DELINEATION; VIRUS ENCEPHALITIS; VIRUS INHIBITION; ADSORPTION; FEMALE; GENETICS; HERPES SIMPLEX; HERPES SIMPLEX ENCEPHALITIS; HERPES SIMPLEX VIRUS 2; NEWBORN; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; PUNCTURE; RECURRENT DISEASE; VIRUS REPLICATION;

ACYCLOVIR; ADMINISTRATION, ORAL; ADSORPTION; ANTIVIRAL AGENTS; DNA, VIRAL; ENCEPHALITIS, HERPES SIMPLEX; FEMALE; HERPES SIMPLEX; HERPESVIRUS 2, HUMAN; HUMANS; INFANT, NEWBORN; POLYMERASE CHAIN REACTION; RECURRENCE; SPINAL PUNCTURE; VIRUS REPLICATION;

EID: 20344383537     PISSN: 00314005     EISSN: 00314005     Source Type: Journal    
DOI: 10.1542/peds.2004-1941     Document Type: Note

References (20)

1. Arvin AM, Whitley RJ. Herpes simples virus infections. In: Infectious Diseases of the Fetus and Newborn Infant. Remington JS, Klein JO, eds. 5th ed. Philadelphia, PA: Saunders; 2001:425-446
2. Whitley RJ, Nahmias AJ, Visintine AM, Fleming CL, Alford CA. The natural history of herpes simplex virus infection of mother and newborn. Pediatrics. 1980;66:489-494
3. Whitley RJ, Yeager A, Kartus P, et al. Neonatal herpes simplex virus infection: follow-up evaluation of vidarabine therapy. Pediatrics. 1983;72:778-785
4. Corey L, Whitley RJ, Stone EF, Mohan K. Difference between herpes simplex virus type 1 and type 2 neonatal encephalitis in neurological outcome. Lancet. 1988;1(8575-6):1-4
5. Whitley R, Arvin A, Prober C, et al. Predictors of morbidity and mortality in neonates with herpes simplex virus infections. The National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. N Engl J Med. 1991;324:450-454
6. Fonseca-Aten M, Messina AF, Jafri HS, Sánchez PJ. Herpes simplex virus encephalitis during suppressive therapy with acyclovir in a premature infant. Pediatrics. 2005;115:804-809
7. Whitley RJ, Corey L, Arvin A, et al. Changing presentation of herpes simplex virus infection in neonates. J Infect Dis. 1988;158:109-116
8. Kimberlin DW, Lakeman FD, Arvin AM, et al. Application of the polymerase chain reaction to the diagnosis and management of neonatal herpes simplex virus disease. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. J Infect Dis. 1996;174:1162-1167
9. Kimberlin DW, Lin CY, Jacobs RF, et al. Natural history of neonatal herpes simplex virus infections in the acyclovir era. Pediatrics. 2001;108:223-229
10. Gutierrez K, Arvin AM. Long term antiviral suppression after treatment for neonatal herpes infection. Pediatr Infect Dis J. 2003;22:371-372
11. Gutman LT, Wilfert CM, Eppes S. Herpes simplex virus encephalitis in children: analysis of cerebrospinal fluid and progressive neurodevelopmental deterioration. J Infect Dis. 1986;154:415-421
12. Kohl S. A hypothesis on the pathophysiology of neonatal herpes simplex virus encephalitis: clinical recurrence after asymptomatic primary infection. Pediatr Infect Dis J. 1990;9:307-308
13. Aurelius E, Johansson B, Skoldenberg B, Staland A, Forsgren M. Rapid diagnosis of herpes simplex encephalitis by nested polymerase chain reaction assay of cerebrospinal fluid. Lancet. 1991;337:189-192
14. Studahl M, Bergstrom T, Hagberg L. Acute viral encephalitis in adults - a prospective study. Scand J Infect Dis. 1998;30:215-220
15. Weil AA, Glaser CA, Amad Z, Forghani B. Patients with suspected herpes simplex encephalitis: rethinking an initial negative polymerase chain reaction result. Clin Infect Dis. 2002;34:1154-1157
16. Diamond C, Mohan K, Hobson A, Frenkel L, Corey L. Viremia in neonatal herpes simplex virus infections. Pediatr Infect Dis J. 1999;18:487-489
17. Whitley RJ, Gnann JW Jr. Acyclovir: a decade later. N Engl J Med. 1992;327:782-789
18. Physicians' Desk Reference. Montvale, NJ: Thomson PDR; 2004:1683-1687
19. Kimberlin DW, Lin CY, Jacobs RF, et al. Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections. Pediatrics. 2001;108:230-238
20. Mandyla H, Anagnostakis D, Koutsovitis P, Siahanidou T, Youroukos S. Late recurrence of herpes simplex virus meningoencephalitis in two infants. Eur J Pediatr. 2001;160:732-735