Total alopecia and severe leukopenia with agranulocytosis complicating the treatment of hand irritant eczema with azathioprine;Całkowite wyłysienie i ciȩżka leukopenia z agranulocytoza̧ jako powikłanie leczenia azatiopryna̧ wyprysku kontaktowego dłoni

Dermatologia Klinicza

Volumn 7, Issue 2, 2005, Pages 89-91

  Reich, Adam ^a   Szepietowski, Jacek ^a  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

Agranulocytosis; Alopecia; Azathioprine; Irritant eczema; Side effects

Indexed keywords

AZATHIOPRINE; GROWTH FACTOR; STEROID;

ADULT; AGRANULOCYTOSIS; ALOPECIA; ARTICLE; CASE REPORT; CLINICAL EXAMINATION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; HAIR GROWTH; HAND ECZEMA; HUMAN; LABORATORY TEST; LEUKOPENIA;

EID: 20344380710     PISSN: 17307201     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Azatiopryna. [w:] Indeks leków medycyny praktycznej. Praca zbiorowa. Wydawnic-two Medycyna Praktyczna, Kraków, 2004, 84.
2. Anstey A.V., Wakelin S., Reynolds N.J.: Guidelines for prescribing azathioprine in dermatology. Br. J. Dermatol., 2004, 151, 1123-1132.
3. Sauer H., Hantke U., Wilmanns W.: Azathioprine lymphocytotoxicity. Potentially lethal demage by its imidazole derivates. Drug Res., 1988, 6, 820-824.
4. Weinsnilboum R.M., Sladek S.L: Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltranferase activity. Am. J. Hum. Genet., 1980, 32, 651-662.
5. Anstey A., Lennard L., Mayou S.C., Kirby J.D.: Pancytopenia related to azathioprine - an enzyme deficiency daused by a common genetic polymorphism: a review. J. R. Soc. Med., 1992, 85, 752-756.
6. Arnott I.D.R., Watts D., Satsangi J.: Azathioprine and anti-TNF-α therapies in Crohn's disease: a review of pharmacology, clinical efficacy and safety. Pharmacol. Res., 2003, 47, 1-10.
7. De Jong D.J., Derijks L.J.J., Naber A.H.J., Hooymans P.M., Mulder C.J.J.: Safety of thiopurines in the treatmentof inflammatory bowel disease. Scand. J. Gastroenterol., 2003, 38, Supl. 239, 69-72.
8. Ansari A., Hassan C., Duley J., Marinaki A., Snobowale-Bakre E.-M., Seed P., Meenan J., Yim A., Sanderson J.: Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease. Aliment. Pharmacol. Tner., 2002, 16, 1743-1750.
9. Kirschner B. S.: Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease. Gastroenterology, 1998, 115, 813-821.
10. Lamers C.B.H.W., Griffioen G., van Hogezand R.A., Veenendaal R.A.: Azathioprine: an update on clinical efficacy and safety in inflammatory bowel disease. Scand. J. Gastroenterol., 1999, 34, Supl. 230, 111-115.
11. Silverstein J., Maclaren N., Riley W., Spillar R., Radjenovic D., Jonnson S.: Immunosuppression with azathioprine and prednisone in recent-onset insulin-dependent diabetes mellitus. N. Engl. J. Med., 1988, 319, 599-604.
12. Craner M.J., Zajicek J.P.: Immunosupressive treatments in MS - side effects from azathioprine. J. Neurol., 2001, 248, 625-626.
13. Usnigome H., Yoshimura N., Okamoto M., Najima H., Hamajima T., Nakai I., Oka T.: Two cases of tacrolimus induced alopecia following kidney transplantation. Transplant. Proceed., 1999, 31, 2885-2886.