Donor MHC class I peptides in conjunction with self-epitopes induce donor-specific tolerance in a dose-dependent manner but unable to abrogate chronic rejection

Transplantation Proceedings

Volumn 37, Issue 4, 2005, Pages 1937-1939

  Semiletova, N V ^a   Shen, X D ^a   Feldman, D M ^a   Busuttil, R W ^a   Kupiec Weglinski, J W ^a   Ghobrial, R M ^a  

^a UCLA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; RT1.A A ANTIGEN; RT1.A L ANTIGEN; RT1.A U ANTIGEN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; CHRONIC GRAFT REJECTION; CONFERENCE PAPER; CONTROLLED STUDY; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL;

ANIMALS; AUTOANTIGENS; GRAFT REJECTION; HISTOCOMPATIBILITY ANTIGENS; HISTOCOMPATIBILITY ANTIGENS CLASS I; IMMUNE TOLERANCE; MODELS, ANIMAL; RATS; RATS, INBRED ACI; RATS, INBRED BN; RATS, INBRED LEW; RATS, INBRED WF;

EID: 20344380190     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2005.02.114     Document Type: Conference Paper

References (8)

1. M. Katz, R. Maizels, L. Wicker Immunological focusing by the mouse MHC mouse strains confronted with distantly related lysozymes confine their attention to a very few epitopes Eur J Immunol 12 1982 535
2. Z. Liu, K.P. Williams, Y.H. Chang Immunodominance a single amino acid substitution within an antigenic site alters intramolecular selection of T cell determinants J Immunol 151 1993 1852
3. J. Sloan-Lancaster, B.D. Evavold, P.M. Allen Induction of T-cell anergy by altered T-cell receptor ligand on live antigen presenting cells Nature 363 1993 156
4. J. Sloan-Lancaster, P.M. Allen Altered peptide ligand-induced partial T cell activation molecular mechanisms and role in T cell biology Annu Rev Immunol 14 1996 1
5. G. Benichou, E. Fedoseyeva, P.V. Lehmann Limited T cell response to donor MHC peptides during allograft rejection J Immunol 153 1994 938
6. D.A. Shoskes, K.J. Wood Indirect presentation of MHC antigens in transplantation Immunol Today 15 1994 32
7. N. Semiltova, X.D. Shen, M.C. Fishbein Posttransplant administration of allochimeric major histocompatibility complex class-I molecules induces true transplantation tolerance Transplantation 75 2003 550
8. a molecules Transplantation 62 1996 1002