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Volumn 46, Issue 27, 2005, Pages 4613-4616

Synthesis of benzimidazole based JNK inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

BENZIMIDAZOLE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; SULFONE DERIVATIVE;

EID: 20344367738     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.04.145     Document Type: Article
Times cited : (14)

References (8)
  • 4
    • 20344364271 scopus 로고    scopus 로고
    • note
    • A typical experimental is as follows: 2,2-dimethyl-5-[2-(methylsulfanyl) anilino]-methylene-1,3-dioxane-4,6-dione (7 g) was added portionwise to stirred diphenyl ether (60 g) at reflux. After addition was complete, heating was continued for 15 min and then the mixture cooled with ice to 50°C. The resulting solution was poured into stirred isohexane (800 ml) and the dark brown precipitate was collected by filtration (4.99 g)
  • 6
    • 20344390125 scopus 로고    scopus 로고
    • note
    • 2O gave the required indole (30.6 g)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.