Sensory representation abnormalities that parallel focal hand dystonia in a primate model

Somatosensory and Motor Research

Volumn 19, Issue 4, 2002, Pages 347-357

  Blake, David T ^a,e   Byl, Nancy N ^b   Cheung, Steven ^a   Bedenbaugh, Purvis ^c   Nagarajan, Srikantan ^d   Lamb, Michelle ^b   Merzenich, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d Department of Electrical and Computer Engineering   (United States)

^e NONE   (United States)

Author keywords

Cerebral cortex; Cortical column; Cortical representation; Focal dystonia; Somatosensory

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY MOVEMENT; CONTROLLED STUDY; DYSTONIA; MECHANORECEPTOR; MICROELECTRODE; MONKEY; MOTOR CONTROL; NONHUMAN; PRIORITY JOURNAL; PROPRIOCEPTION; RECEPTIVE FIELD; SENSORY STIMULATION; STEREOTYPY; STIMULUS RESPONSE; TASK PERFORMANCE;

ANIMALS; AOTIDAE; BRAIN MAPPING; CEREBRAL CORTEX; CONDITIONING, OPERANT; DISEASE MODELS, ANIMAL; DYSTONIC DISORDERS; FACE; FUNCTIONAL LATERALITY; HAND; HAND STRENGTH; HUMANS; MOTOR NEURONS; NERVE NET; SOMATOSENSORY CORTEX; STEREOTYPED BEHAVIOR; THALAMUS;

EID: 20244374647     PISSN: 08990220     EISSN: None     Source Type: Journal    
DOI: 10.1080/0899022021000037827     Document Type: Article

References (48)

1. Alexander, G.E., M.R. Delong, and P.L. Strick (1986) Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Ann Rev Neurosci 9: 357-381.
2. Bara-Jimenez, W., M.J. Catalan, M. Hallett, and C. Gerloff (1998) Abnormal somatosensory homunculus in dystonia of the hand. Ann Neurol 44: 828-831.
3. Blake, D.T., S.S. Hsiao, and K.O. Johnson (1997) Neural coding mechanisms in tactile pattern recognition: The relative contributions of slowly and rapidly adapting mechanoreceptors to perceived roughness. J Neurosci 17: 7480-7489.
4. Byl, N.N., A. McKenzie, and S.S. Nagarajan (2000) Differences in somatosensory hand organization in a healthy flutist and a flutist with focal hand dystonia: A case report. J Hand Ther 13: 302-309.
5. Byl, N.N., M.M. Merzenich, S. Cheung, P. Bedenbaugh, S.S. Nagarajan, and W.M. Jenkins (1997) A primate model for studying focal dystonia and repetitive strain injury: Effects on the primary somatosensory cortex. Phys Ther 77: 269-284.
6. Byl, N.N., M.M. Merzenich, and W.M. Jenkins (1996) A primate genesis model of focal dystonia and repetitive strain injury: I. Learning-induced dedifferentiation of the representation of the hand in the primary somatosensory cortex in adult monkeys. Neurology 47: 508-520.
7. Chen, R.S., C.H. Tsai, and C.S. Lu (1995) Reciprocal inhibition in writer's cramp. Mov Disord 10: 556-561.
8. Cohen, L.G., M. Hallett, B.D. Geller, and F. Hochberg (1989) Treatment of focal dystonias of the hand with botulinum toxin injections. J Neurol Neurosurg Psych 52: 355-363.
9. deCharms, R.C., D.T. Blake, and M.M. Merzenich (1999) A multielectrode implant device for the cerebral cortex. J Neurosci Meth 93: 27-35.
10. Defazio, G., P. Lamberti, V. Lepore, P. Livrea, and E. Ferrari (1989) Facial dystonia: Clinical features, prognosis and pharmacology in 31 patients. Ital J Neurol Sci 10: 553-560.
11. Elbert, T., V. Candia, E. Altenmuller, H. Rau, A. Sterr, B. Rockstroch, C. Pantev, and E. Taub (1998) Alteration of digital representations in somatosensory cortex in focal hand dystonia. Neuroreport 9: 3571-3575.
12. Greene, P., U.J. Kang, and S. Fahn (1995) Spread of symptoms in idiopathic torsion dystonia. Mov Disord 10: 143-152.
13. Hikosaka, O., M. Tanaka, M. Sakamoto, and Y. Iwamura (1985) Deficits in manipulative behaviors induced by local injections of muscimol in the first somatosensory cortex of the conscious monkey. Brain Res 325: 375-380.
14. Johansson, R.S., and G. Westling (1987) Signals in tactile afferents from the fingers eliciting adaptive motor responses during precision grip. Exp Brain Res 66: 141-154.
15. Johnson, K.O., and G.D. Lamb (1981) Neural mechanisms of spatial tactile discrimination: Neural patterns evoked by braille-like dot patterns in the monkey. J Physiol 310: 117-144.
16. Jones, E.G. (1985) The Thalamus, Plenum Press, New York.
17. Jones, E.G., J.D. Coulter, and S.H. Hendry (1978) Intracorfical connectivity of architectonic fields in the somatic sensory, motor and parietal cortex of monkeys. J Comp Neurol 181: 291-347.
18. Kaas, J.H., R.J. Nelson, M. Sur, R.W. Dykes, and M.M. Merzenich (1984) The somatotopic organization of the ventroposterior thalamus of the squirrel monkey, Saimiri sciureus. J Comp Neurol 226: 111-140.
19. LaMotte, R.H., and J. Whitehouse (1986) Tactile detection of a dot on a smooth surface: Peripheral neural events. J Neurophysiol 56: 1109-1128.
20. Lenz, F.A., and N.N. Byl (1999) Reorganization in the cutaneous core of the human thalamic principal somatic sensory nucleus (ventral caudal) in patients with dystonia. J Neurophysiol 82: 3204-3212.
21. Lenz, F.A., C.J. Jaeger, M.S. Seike, Y.C. Lin, S.G. Reich, M.R. DeLong, and J.L Vitek (1999) Thalamic single neuron activity in patients with dystonia: Dystonia-related activity and somatic sensory reorganization. J Neurophysiol 82: 2372-2392.
22. Lockwood, A.H. (1989) Medical problems of musicians [see comments]. New Engl J Med 320: 221-227.
23. Macefield, V.G., C. Hager-Ross, and R.S. Johansson (1996) Control of grip force during restraint of an object held between finger and thumb: Responses of cutaneous afferents from the digits. Exp Brain Res 108: 155-171.
24. Macefield, V.G., and R.S. Johansson (1996) Control of grip force during restraint of an object held between finger and thumb: Responses of muscle and joint afferents from the digits. Exp Brain Res 108: 172-184.
25. Marsden, C.D., and M.P. Sheehy (1990) Writer's cramp. Trends Neurosci 13: 148-153.
26. Merzenich, M.M., J.H. Kaas, M. Sur, and C.S. Lin (1978) Double representation of the body surface within cytoarchitectonic areas 3b and 1 in SI in the owl monkey (Aotus trivirgatus). J Comp Neurol 181: 41-73.
27. Merzenich, M.M., R.J. Nelson, J.H. Kaas, M.P. Stryker, W.M. Jenkins, J.M. Zook, M.S. Cynader, and A. Schoppmann (1987) Variability in hand surface representations in areas 3b and 1 in aclult owl and squirrel monkeys. J Comp Neurol 258: 281-296.
28. Mountcastle, V.B. (1984) Central nervous mechanisms in mechanoreceptive sensibility. In The Handbook of Physiology - The Nervous System Vol. III, pp. 784-878. American Physiology Society, Bethesda, MD.
29. Mountcastle, V.B., and E. Henneman (1952) The representation of tactile sensibility in the thalamus of the monkey. J Comp Neurol 97: 409-440.
30. Mountcastle, V.B., W.H. Talbot, H. Sakata, and J. Hyvarinen (1969) Cortical neuronal mechanisms in flutter-vibration studied in unanesthetized monkeys. Neuronal periodicity and frequency discrimination. J Neurophysiol 32: 452-484.
31. Newmark, J., and F.H. Hochberg (1987) Isolated painless manual incoordination in 57 musicians. J Neurol Neurosurg Psych 50: 291-295.
32. Odergren, T., N. Iwasaki, J. Borg, and H. Forssberg (1996) Impaired sensory-motor integration during grasping in writer's cramp. Brain 119: 569-583.
33. Peterson, B.E., and M.M. Merzenich (1995) Map: A Macintosh program for generating categorical maps applied to cortical mapping. J Neurosci Meth 57: 33-144.
34. Phillips, J.R., and K.O. Johnson (1981) Tactile spatial resolution. II. Neural representation of bars, edges, and gratings in monkey primary afferents. J Neurophysiol 46: 1192-1203.
35. Poggio, G.F., and V.B. Mountcastle (1963) The functional properties of ventrobasal thalamic neurons studied in unanesthetized monkeys. J Neurophysiol 26: 775-806.
36. Powell, T.P., and V. B. Mountcastle (1959) Some aspects of the functional organization of the cortex of the postcentral gyrus of the monkey: A correlation of findings obtained in a single unit analysis with cytoarchitecture. Bull Johns Hopkins Hosp 105: 133-162.
37. Randolph, M., and J. Semmes (1974) Behavioral consequences of selective subtotal ablations in the postcentral gyrus of Macaca mulatta. Brain Res 70: 55-70.
38. Rausell, E., and E.G. Jones (1995) Extent of intracortical arborization of thalamocortical axons as a determinant of representational plasticity in monkey somatic sensory cortex. J Neurosci 15: 4270-4288.
39. Recanzone, G.H., M.M. Merzenich, W.M. Jenkins, K.A. Grajski, and H.R. Dinse (1992) Topographic reorganization of the hand representation in cortical area 3b owl monkeys trained in a frequency-discrimination task. J Neurophysiol 67: 1031-1056.
40. Rothwell, J.C., J.A. Obeso, B.L. Day, and C.D. Marsden (1983) Pathophysiology of dystonias. Adv Neurol 39: 851-863.
41. Sanger, T.D., and M.M. Merzenich (2000) Computational model of the role of sensory disorganization in focal task-specific dystonia. J Neurophysiol 84: 2458-2464.
42. Sheehy, M.P., and C.D. Marsden (1982) Writers' cramp - A focal dystonia. Brain 105: 461-480.
43. Srinivasan, M.A., and R.H. LaMotte (1995) Tactual discrimination of softness. J Neurophysiol 73: 88-101.
44. Stryker, M.P., W.M. Jenkins, and M.M. Merzenich (1987) Anesthetic state does not affect the map of the hand representation within area 3b somatosensory cortex in owl monkey. J Comp Neurol 258: 297-303.
45. Sur, M., M.M. Merzenich, and J.H. Kaas (1980) Magnification, receptive-field area, and hypercolumn size in areas 3b and 1 of somatosensory cortex in owl monkeys. J Neurophysiol 44: 295-311.
46. Tempel, L.W., and J.S. Perlmutter (1993) Abnormal cortical responses in patients with writer's cramp. Neurol 43: 2252-2257.
47. Wang, X., M.M. Merzenich, K. Sameshima, and W. M. Jenkins (1995) Remodelling of hand representation in adult cortex determined by timing of tactile stimulation. Nature 378: 71-75.
48. Wilson, F.R. (1989) Acquisition and loss of skilled movement in musicians. Semin Neurol 9: 146-151.