Identification, molecular cloning and functional characterization of NKp46 and NKp30 natural cytotoxicity receptors in Macaca fascicularis NK cells

European Journal of Immunology

Volumn 31, Issue 12, 2001, Pages 3546-3556

  De Maria, Andrea ^a,c   Biassoni, Roberto ^b   Fogli, Manuela ^d   Rizzi, Marta ^a   Cantoni, Claudia ^c,d   Costa, Paola ^a   Conte, Romana ^b   Mavilio, Domenico ^a   Ensoli, Barbara ^e   Cafaro, Aurelio ^e   Moretta, Alessandro ^c   Moretta, Lorenzo ^c,d  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d G GASLINI INSTITUTE   (Italy)

^e ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

HIV 1; Macaca fascicularis; Natural cytotoxicity receptor; NK cell; SIV

Indexed keywords

CELL RECEPTOR; MONOCLONAL ANTIBODY; RECEPTOR SUBTYPE;

ANIMAL CELL; ARTICLE; ASSAY; CELL KILLING; CONTROLLED STUDY; CYTOFLUOROMETRY; CYTOLYSIS; GENETIC CONSERVATION; GENETIC TRANSFECTION; HOST RESISTANCE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNITY; IMMUNOREACTIVITY; INFECTION; LYMPHOCYTE CLONE; LYMPHOCYTE CULTURE; LYMPHOCYTE FUNCTION; LYMPHOCYTE SUBPOPULATION; MACACA; MOLECULAR CLONING; MONONUCLEAR CELL; NATURAL KILLER CELL; NONHUMAN; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ISOLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SIMIAN IMMUNODEFICIENCY VIRUS;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; CYTOTOXICITY, IMMUNOLOGIC; KILLER CELLS, NATURAL; MACACA FASCICULARIS; MOLECULAR SEQUENCE DATA; RECEPTORS, IMMUNOLOGIC; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME;

EID: 20244372510     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200112)31:12<3546::AID-IMMU3546>3.0.CO;2-W     Document Type: Article

References (36)

1. Human NK-cell receptors
2. NK cell receptors
3. Receptors for HLA class I molecules in human Natural Killer cells
4. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis
5. Natural killer cells in antiviral defense: Function and regulation by innate cytokines
6. Control of SHIV-89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccine
7. Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P)
8. Cytokine expression natural killer cell activation and phenotypic changes in lymphoid cells from rhesus macaques during acute infection with pathogenic simian immunodeficiency virus
9. The immuno-pathogenesis of retroviral diseases: No immunophenotypic alterations in T, B, and NK cell subsets in SIVmac239-challenged rhesus macaques protected by SIV delta nef vaccination
10. + nef-specific cytotoxic T cells in vaccinated macaques
11. Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques
12. Rapid evolution on NK cell receptor systems demonstrated by comparison of chimpanzees and humans
13. Short KIR haplotypes in pygmy chimpanzee (bonobo) resemble the conserved framework of diverse human KIR haplotypes
14. Diversity of the killer Ig-like receptors of Rhesus monkeys
15. + monocyte subset with phenotypic similarity to primate natural killer cells
16. CD56 identifies monocytes and not natural killer cells in rhesus macaques
17. Molecular cloning of NKp46: A novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity
18. The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity
19. Identification of the rat homologue of the human NKp46 triggering receptor
20. NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis
21. Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells
22. Plasticity in the organization and sequences of human KIR/ILT gene families
23. A molecular timescale for vertebrate evolution
24. Genes in a 220-kb region spanning the TNF cluster in human MHC
25. A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC
26. Isolation of foamy virus from rhesus, African green and cynomolgus monkey Leukocytes
27. Sites of simian foamy virus persistence in naturally infected African green monkeys: Latent provirus is ubiquitous, whereas viral replication is restricted to the oral mucosa
28. High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys
29. Persistent infection of macaques with simian-human immunodeficiency viruses
30. High viral load and CD4 lymphopenia in rhesus and cynomolgus macaques infected by a chimeric primate lentivirus constructed using the env, rev, tat, and vpu genes from HIV-1 Lai
31. NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily
32. NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, xenogeneic target cells
33. The activating form of CD94 receptor complex: CD94 covalently associates with the Kp39 protein that represents the product of the NKG2-G gene
34. p46, a novel natural killer cell-specific surface molecule that mediates cell activation
35. p58 molecules as putative receptors for MHC class I molecules in human Natural Killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities
36. The natural killer cell receptor specific for HLA-A allotypes: A novel member of the p58/p70 family of inhibitory receptors which is characterized by three Ig-like domains and is expressed as a 140 kD disulphide-linked dimer