Genetic distinctions between autoimmune hepatitis in Italy and North America

World Journal of Gastroenterology

Volumn 11, Issue 12, 2005, Pages 1862-1866

  Muratori, Paolo ^a,c   Czaja, Albert J ^b   Muratori, Luigi ^a   Pappas, Georgios ^a   Maccariello, Silvana ^a   Cassani, Fabio ^a   Granito, Alessandro ^a   Ferrari, Rodolfo ^a   Mantovani, Vilma ^a   Lenzi, Marco ^a   Bianchi, Francesco B ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b MAYO CLINIC   (United States)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Human leukocyte antigen; Type 1 autoimmune hepatitis; Type 2 autoimmune hepatitis

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ANTINUCLEAR ANTIBODY; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; HLA B8 ANTIGEN; HLA C ANTIGEN; HLA DQ2 ANTIGEN; HLA DR11 ANTIGEN; HLA DR3 ANTIGEN; HLA DR4 ANTIGEN; HLA DR7 ANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MICROSOME ANTIBODY; SMOOTH MUSCLE ANTIBODY;

ADULT; AGED; ARTICLE; AUTOIMMUNE HEPATITIS; CONTROLLED STUDY; DISEASE CLASSIFICATION; FEMALE; FISHER EXACT TEST; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; HUMAN; ITALY; LYMPHOCYTOTOXICITY; MAJOR CLINICAL STUDY; MALE; NORTH AMERICA; PHENOTYPE; POLYMERASE CHAIN REACTION; RISK FACTOR; STUDENT T TEST;

EID: 20244370597     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i12.1862     Document Type: Article

References (33)

1. Czaja AJ. Treatment of autoimmune hepatitis. Semin Liver Dis 2002; 22: 365-378
2. Czaja AJ, Homburger HA. Autoantibodies in liver disease. Gastroenterology 2001; 120: 239-249
3. Donaldson PT, Doherty DG, Hayllar KM, McFarlane IG, Johnson PJ, Williams R. Susceptibility to autoimmune chronic active hepatitis: Human leukocyte antigens DR4 and A1-B8-DR3 are independent risk factors. Hepatology 1991; 13: 701-706
4. Manabe K, Donaldson PT, Underhill JA, Doherty DG, Mieli-Vergani G, McFarlane IG, Eddleston AL, Williams R. Human leukocyte antigen A1-B8-DR3-DQ2-DPB1*0401 extended haplotype in autoimmune hepatitis. Hepatology 1993; 18: 1334-1337
5. Czaja AJ, Strettell MD, Thomson LJ, Santrach PJ, Moore SB, Donaldson PT, Williams R. Associations between alleles of the major histocompatibility complex and type 1 autoimmune hepatitis. Hepatology 1997; 25: 317-323
6. Strettell MD, Donaldson PT, Thomson LJ, Santrach PJ, Moore SB, Czaja AJ, Williams R. Allelic basis for HLA-encoded susceptibility to type 1 autoimmune hepatitis. Gastroenterology 1997; 112: 2028-2035
7. Pando M, Larriba J, Fernandez GC, Fainboim H, Ciocca M, Ramonet M, Badia I, Daruich J, Findor J, Tanno H, Canero-Velasco C, Fainboim L. Pediatric and adult forms of type I autoimmune hepatitis in Argentina: Evidence for differential genetic predisposition. Hepatology 1999; 30: 1374-1380
8. Seki T, Ota M, Furuta S, Fukushima H, Kondo T, Hino K, Mizuki N, Ando A, Tsuji K, Inoko H. HLA class II molecules and autoimmune hepatitis susceptibility in Japanese patients. Gastroenterology 1992; 103: 1041-1047
9. Vazquez-Garcia MN, Alaez C, Olivo A, Debaz H, Perez-Luque E, Burguete A, Cano S, de la Rosa G, Bautista N, Hernandez A, Bandera J, Torres LF, Kershenobich D, Alvarez F, Gorodezky C. MHC class II sequences of susceptibility and protection in Mexicans with autoimmune hepatitis. J Hepatol 1998; 28: 985-990
10. Fainboim L, Canero Velasco MC, Marcos CY, Ciocca M, Roy A, Theiler G, Capucchio M, Nuncifora S, Sala L, Zelazko M. Protracted, but not acute, hepatitis A virus infection is strongly associated with HLA-DRB*1301, a marker for pediatric autoimmune hepatitis. Hepatology 2001; 33: 1512-1517
11. Fainboim L, Marcos Y, Pando M, Capucchio M, Reyes GB, Galoppo C, Badia I, Remondino G, Ciocca M, Ramonet M. Chronic active autoimmune hepatitis in children. Strong association with a particular HLA-DR6 (DRB1*1301) haplotype. Hum Immunol 1994; 41: 146-150
12. Goldberg AC, Bittencourt PL, Mougin B, Cancado EL, Porta G, Carrilho F, Kalil J. Analysis of HLA haplotypes in autoimmune hepatitis type 1: Identifying the major susceptibility locus. Hum Immunol 2001; 62: 165-169
13. Czaja AJ, Souto EO, Bittencourt PL, Cancado EL, Porta G, Goldberg AC, Donaldson PT. Clinical distinctions and pathogenic implications of type 1 autoimmune hepatitis in Brazil and the United States. J Hepatol 2002; 37: 302-308
14. Invernizzi P, Battezzati PM, Crosignani A, Perego F, Poli F, Morabito A, De Arias AE, Scalamogna M, Zuin M, Podda M. Peculiar HLA polymorphisms in Italian patients with primary biliary cirrhosis. J Hepatol 2003; 38: 401-406
15. Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Significance of HLA DR4 in type 1 autoimmune hepatitis. Gastroenterology 1993; 105: 1502-1507
16. Czaja AJ, Kruger M, Santrach PJ, Moore SB, Manns MP. Genetic distinctions between types 1 and 2 autoimmune hepatitis. Am J Gastroenterol 1997; 92: 2197-2200
17. Bittencourt FL, Goldberg AC, Cancado EL, Porta G, Carrilho FJ, Farias AQ, Palacios SA, Chiarella JM, Abrantes-Lemos CP, Baggio VL, Laudanna AA, Kalil J. Genetic heterogeneity in susceptibility to autoimmune hepatitis types 1 and 2. Am J Gastroenterol 1999; 94: 1906-1913
18. Jurado A, Cardaba B, Jara P, Cuadrado P, Hierro L, de Andres B, del Pozo V, Cortegano MI, Gallardo S, Camarena C, Barcena R, Castaner JL, Alvarez R, Lahoz C, Palomino P. Autoimmune hepatitis type 2 and hepatitis C virus infection: Study of HLA antigens. J Hepatol 1997; 26: 983-991
19. Alvarez F, Berg PA, Bianchi FB, Bianchi L, Burroughs AK, Cancado EL, Chapman RW, Cooksley WG, Czaja AJ, Desmet VJ, Donaldson PT, Eddleston AL, Fainboim L, Heathcote J, Homberg JC, Hoofnagle JH, Kakumu S, Krawitt EL, Mackay IR, MacSween RN, Maddrey WC, Manns MP, McFarlane IG, Meyer zum Buschenfelde KH, Zeniya M. International Autoimmune Hepatitis Group Report: Review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999; 31: 929-938
20. Cassani F, Cataleta M, Valentini P, Muratori P, Giostra F, Francesconi R, Muratori L, Lenzi M, Bianchi G, Zauli D, Bianchi FB. Serum autoantibodies in chronic hepatitis C: Comparison with autoimmune hepatitis and impact on the disease profile. Hepatology 1997; 26 561-566
21. Muratori P, Muratori L, Agostinelli D, Pappas G, Veronesi L, Granito A, Cassani F, Terlizzi P, Lenzi M, Bianchi FB. Smooth muscle antibodies and type 1 autoimmune hepatitis. Autoimmunity 2002; 35: 497-500
22. Cassani F, Bianchi FB, Lenzi M, Volta U, Pisi E. Immunomorphological characterisation of antinuclear antibodies in chronic liver disease. J Clin Pathol 1985; 38: 801-805
23. Czaja AJ, Cassani F, Cataleta M, Valentini P, Bianchi FB. Antinuclear antibodies and patterns of nuclear immunofluorescence in type 1 autoimmune hepatitis. Dig Dis Sci 1997; 42: 1688-1696
24. Czaja AJ, Manns MP, Homburger HA. Frequency and significance of antibodies to liver/kidney microsome type 1 in adults with chronic active hepatitis. Gastroenterology 1992; 103: 1290-1295
25. Mantovani V, Martinelli G, Bragliani M, Buzzi M, Selva P, Collina E, Farabegoli P, Rosti GA, Bandini G, Tura S. Molecular analysis of HLA genes for the selection of unrelated bone marrow donor. Bone Marrow Transplant 1995; 16: 329-335
26. Terasaki PI, Bernoco D, Park MS, Ozturk G, Iwaki Y. Microdroplet testing for HLA-A, -B, -C, and -D antigens. The Phillip Levine Award Lecture. Am J Clin Pathol 1978; 69: 103-120
27. Czaja AJ, Carpenter H, Santrach PJ, Moore SB. DR human leukocyte antigens and disease severity in chronic hepatitis C. J Hepatol 1996; 24: 666-673
28. Mackay IR, Tait BD. HLA associations with autoimmune-type chronic active hepatitis: Identification of B8-DRw3 haplotype by family studies. Gastroenterology 1980; 79: 95-98
29. Doherty DG, Donaldson PT, Underhill JA, Farrant JM, Duthie A, Mieli-Vergani G, McFarlane IG, Johnson PJ, Eddleston AL, Mowat AP. Allelic sequence variation in the HLA class II genes and proteins in patients with autoimmune hepatitis. Hepatology 1994; 19: 609-615
30. Seki T, Kiyosawa K, Inoko H, Ota M. Association of autoimmune hepatitis with HLA-Bw54 and DR4 in Japanese patients. Hepatology 1990; 12: 1300-1304
31. Strettell MD, Thomson LJ, Donaldson PT, Bunce M, O'Neill CM, Williams R. HLA-C genes and susceptibility to type 1 autoimmune hepatitis. Hepatology 1997; 26: 1023-1026
32. Senaldi G, Portmann B, Mowat AP, Mieli-Vergani G, Vergani D. Immunohistochemical features of the portal tract mononuclear cell infiltrate in chronic aggressive hepatitis. Arch Dis Child 1992; 67: 1447-1453
33. Takeda K, Hayakawa Y, Van Kaer L, Matsuda H, Yagita H, Okumura K. Critical contribution of liver natural killer T cells to a murine model of hepatitis. Proc Natl Acad Sci USA 2000; 97: 5498-5503