Risk factors for new detection of vancomycin-resistant enterococci in acute-care hospitals that employ strict infection control procedures

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 8, 2003, Pages 2492-2498

  Padiglione, Alexander A ^a,b   Wolfe, Rory ^b   Grabsch, Elizabeth A ^a,c   Olden, Di ^a   Pearson, Stephen ^c   Franklin, Clare ^d   Spelman, Denis ^d   Mayall, Barrie ^c   Johnson, Paul D R ^a,c   Grayson, M Lindsay ^a,b,c  

^a MONASH MEDICAL CENTRE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c AUSTIN HEALTH   (Australia)

^d ALFRED HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; AZATHIOPRINE; CARBAPENEM; CEFEPIME; CEFOTAXIME; CEFPIROME; CEFTAZIDIME; CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; CYCLOSPORIN; GENTAMICIN; IMIPENEM; IMMUNOSUPPRESSIVE AGENT; MEROPENEM; METRONIDAZOLE; MYCOPHENOLIC ACID; PIPERACILLIN PLUS TAZOBACTAM; PREDNISOLONE; TACROLIMUS; TEICOPLANIN; TIMENTIN; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL TRANSMISSION; BACTERIUM DETECTION; DRUG MONITORING; ENTEROCOCCUS; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; FEMALE; HIGH RISK PATIENT; HOSPITAL CARE; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; INTENSIVE CARE UNIT; KIDNEY DISEASE; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; PULSED FIELD GEL ELECTROPHORESIS; RISK FACTOR; TEACHING HOSPITAL;

ADULT; ANTI-BACTERIAL AGENTS; CROSS INFECTION; DRUG MONITORING; DRUG UTILIZATION; ENTEROCOCCUS; FEMALE; HUMANS; INFECTION CONTROL; MALE; RECTUM; RISK FACTORS; VANCOMYCIN RESISTANCE;

EID: 20244363460     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.8.2492-2498.2003     Document Type: Article

References (35)

1. Bell, J., J. Paton, and J. Turnidge. 1998. Emergence of vancomycin-resistant enterococci in Australia: phenotypic and genotypic characteristics of isolates J. Clin. Microbiol. 36:2187-2190.
2. Bennett, W. M. 1995. Drug prescribing in renal failure, 3rd ed. American College of Physicians, Philadelphia, Pa.
3. Centers for Disease Control and Prevention. 1993. Nosocomial enterococci resistant to vancomycin - United States, 1989-1993. Morb. Mortal. Wkly. Rep. 42:597-599.
4. Centers for Disease Control and Prevention. 1996. Guidelines for isolation precautions in hospitals. Am. J. Infect. Control 24:24-52.
5. Clayton, D., and M. Hills. 1993. Statistical models in epidemiology. Oxford University Press, Oxford, United Kingdom.
6. Coque, T., J. F. Tomayko, S. C. Ricke, P. C. Okyusen, and B. E. Murray. 1996. Vancomycin-resistant enterococci from nosocomial community and animal sources in the United States. Antimicrob. Agents Chemother. 40: 2605-2609.
7. D'Agata, E. M., S. Gautam, W. K. Green, and Y. W. Tang. 2002. High rate of false-negative results of the rectal swab culture method in detection of gastrointestinal colonization with vancomycin-resistant enterococci. Clin. Infect. Dis. 34:167-172.
8. Dan, M., F. Poch, L. Leibson, S. Smetana, and I. Priel. 1999. Rectal colonization with vancomycin-resistant enterococci among high-risk patients in an Israeli hospital. J. Hosp. Infect. 43:231-238.
9. Donskey, C. J., T. K. Chowdhry, M. T. Hecker, C. K. Hoyen, J. A. Hanrahan, A. M. Hujer, R. A. Hutton-Thomas, C. C. Whalen, R. A. Bonomo, and L. B. Rice. 2000. Effect of antibiotic therapy on the density of vancomycin-resistant enterococci in the stool of colonized patients. N. Engl. J. Med. 343:1925-1932.
10. Donskey, C. J., J. A. Hanrahan, R. A. Hutton, and L. B. Rice. 1999. Effect of parenteral antibiotic administration on persistence of vancomycin-resistant Enterococcus faecium in the mouse gastrointestinal tract. J. Infect. Dis. 180: 384-390.
11. Donskey, C. J., J. A. Hanrahan, R. A. Hutton, and L. B. Rice. 2000. Effect of parenteral antibiotic administration on the establishment of colonization with vancomycin-resistant Enterococcus faecium in the mouse gastrointestinal tract. J. Infect. Dis. 181:1830-1833.
12. Donskey, C. J., J. R. Schreiber, M. R. Jacobs, R. Shekar, R. A. Salata, S. Gordon, C. C. Whalen, F. Smith, L. B. Rice, et al. 1999. A polyclonal outbreak of predominantly VanB vancomycin-resistant enterococci in northeast Ohio. Clin. Infect Dis. 29:573-579.
13. Dutka-Malen, A., S. Evers, and P. Courvalin. 1995. Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR. J. Clin. Microbiol. 33:24-27.
14. Endtz, H. P., N. van den Braak, A. van Belkum, J. A. Kluytmans, J. G. Koeleman, L. Spanjaard, A. Voss, A. J. Weersink, C. M. Vandenbroucke-Grauls, A. G. Buiting, A. van Duin, and H. A. Verbrugh. 1997. Fecal carriage of vancomycin-resistant enterococci in hospitalized patients and those living in the community in The Netherlands. J. Clin. Microbiol. 35:3026-3031.
15. Facklam, R. R., D. Sahm, and L. M. Teixeira. 1999. Enterococcus, p. 297-305. In P. R. Murray, E. J. Baron, M. A. Pfaller, F. C. Tenover, and R. H. Yolken (ed.), Manual of clinical microbiology, 7th ed. American Society for Microbiology, Washington, D.C.
16. Gambarotto, K., M. C. Ploy, P. Turlure, C. Grelaud, C. Martin, D. Bordessoule, and F. Denis. 2000. Prevalence of vancomycin-resistant enterococci in fecal samples from hospitalized patients and nonhospitalized controls in a cattle-rearing area of France. J. Clin. Microbiol. 38:620-624.
17. Grayson, M. L., E. A. Grabsch, P. D. Johnson, D. Olden, M. Aberline, H. Y. Li, G. Hogg, M. Abbott, and P. G. Kerr. 1999. Outcome of a screening program for vancomycin-resistant enterococci in a hospital in Victoria. Med. J. Aust. 171:133-136.
18. Harbath, S., S. Cosgrove, and Y. Carmeli. 2002. Effects of antibiotics on nosocomial epidemiology of vancomycin-resistant enterococci. Antimicrob. Agents Chemother. 46:1619-1628.
19. Harris, A. D., T. B. Karchmer, Y. Carmeli, and M. H. Samore. 2001. Methodological principles of case-control studies that analyzed risk factors for antibiotic resistance: a systematic review. Clin. Infect. Dis. 32:1055-1061.
20. Hospital Infection Control Practices Advisory Committee. 1995. Recommendations for preventing the spread of vancomycin resistance. Infect. Control Hosp. Epidemiol. 16:105-113.
21. Jordens, J. Z., J. Bates, and D. T. Griffiths. 1994. Faecal carriage and nosocomial spread of vancomycin-resistant Enterococcus faecium. J. Antimicrob. Chemother. 34:515-528.
22. Miranda, A. G., K. V. Singh, and B. E. Murray. 1991. DNA fingerprinting of Enterococcus faecium by pulsed-field gel electrophoresis may be a useful epidemiologic tool. J. Clin. Microbiol. 29:2752-2757.
23. Moreno, F., P. Grota, C. Crisp, K. Magnon, G. P. Melcher, J. H. Jorgensen, and J. E. Patterson. 1995. Clinical and molecular epidemiology of vancomycin-resistant Enterococcus faecium during its emergence in a city in southern Texas. Clin. Infect. Dis. 21:1234-1237.
24. Padiglione, A., E. Grabsch, R. Wolfe, K. Gibson, and M. L. Grayson. 2001. The prevalence of fecal colonization with VRE among residents of longterm-care facilities in Melbourne, Australia. Infect. Control Hosp. Epidemiol. 22:576-578.
25. Padiglione, A. A., E. A. Grabsch, D. Olden, M. Hellard, M. I. Sinclair, C. K. Fairley, and M. L. Grayson. 2000. Fecal colonisation with vancomycin-resistant enterococci in Australia. Emerg. Infect. Dis. 6:534-536.
26. Rice, L. B. 2001. Emergence of vancomycin-resistant enterococci. Emerg. Infect. Dis. 7:183-187.
27. Roghmann, M. C., J. C. Fink, L. Polish, T. Maker, J. Brewrink, J. G. Morris, and P. D. Light. 1998. Colonisation with vancomycin-resistant enterococci in chronic haemodialysis patients. Am. J. Kidney Dis. 32:254-257.
28. Standing Committee on Infection Control. 1999. Guidelines for the management of patients with vancomycin-resistant enterococci (VRE) colonisation/infection. Department of Human Services, Melbourne, Australia.
29. Stinear, T. P., D. C. Olden, P. D. Johnson, J. K. Davies, and M. L. Grayson. 2001. Enterococcal vanB resistance locus in anaerobic bacteria in human faeces. Lancet 357:855-856.
30. Tenover, F. C., R. D. Arbeit, R. V. Goering, P. A. Mickelsen, B. E. Murray, D. H. Persing, and B. Swaminathan. 1995. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 33:2233-2239.
31. Tokars, J. I., S. Satake, D. Rimland, L. Carson, E. R. Miller, E. Killum, R. L. Sinkowitz-Cochran, M. J. Arduino, F. C. Tenover, B. Marston, and W. R. Jarvis. 1999. The prevalence of colonization with vancomycin-resistant Enterococcus at a Veterans' Affairs institution. Infect. Control Hosp. Epidemiol. 20:171-175.
32. Tornieport, N. G., R. B. Roberts, J. John, A. Hafner, and L. W. Riley. 1996. Risk factors associated with vancomycin-resistant Enterococcus faecium infection or colonization in 145 matched case patients and control patients. Clin. Infect. Dis. 23:767-772.
33. van den Bogaard, A. E., L. B. Jensen, and E. E. Stobberingh. 1997. Vancomycin-resistant enterococci in turkeys and farmers. N. Engl. J. Med. 337: 1558-1559.
34. Van der Auwera, P., N. Pensart, V. Korten, B. Murray, and R. Leclercq. 1996. Influence of oral glycopeptides on the fecal flora of human volunteers: selection of highly glycopeptide-resistant enterococci. J. Infect. Dis. 173: 1129-1136.
35. Wells, C. L., B. A. Juni, S. B. Cameron, K. R. Mason, D. L. Dunn, P. Ferrieri, and F. S. Rhame. 1994. Stool carriage, clinical isolation, and mortality during an outbreak of VRE in hospitalized medical and/or surgical patients. Clin. Infect. Dis. 21:45-50.