Comparison of different cyclosporine immunoassays to monitor C0 and C2 blood levels from kidney transplant recipients: Not simply overestimation

Clinica Chimica Acta

Volumn 355, Issue 1-2, 2005, Pages 153-164

  Cattaneo, Dario ^a,b,c   Zenoni, Stefania ^a,b   Murgia, Stefano ^a,b   Merlini, Simona ^a,b   Baldelli, Sara ^a,b   Perico, Norberto ^a,b   Gotti, Eliana ^a   Ottomano, Cosimo ^a   Crippa, Alberto ^a   Remuzzi, Giuseppe ^a,b  

^a OSPEDALI RIUNITI   (Italy)

^b Center for Research on Organ Transplantation   (Italy)

^c MARIO NEGRI INST PHARMACOL RES   (Italy)

Author keywords

Cyclosporine; HPLC; Immunoassays; Methods comparison

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN; CYCLOSPORIN A; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG BLOOD LEVEL; DRUG MONITORING; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOASSAY; INTERMETHOD COMPARISON; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; MALE; PRIORITY JOURNAL; RECIPIENT; VALIDATION PROCESS;

EID: 20144389181     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cccn.2004.12.018     Document Type: Article

References (30)

1. D. Faulds, K.L. Goa, and Benfield P. Cyclosporin A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders Drugs 45 1993 953 1040
2. S. Pollard, B. Nashan, A. Johnston, P. Hoyer, P. Belitsky, and P. Keown A pharmacokinetic and clinical review of the potential clinical impact of using different formulations of cyclosporin A Clin. Ther. 25 6 2003 Jun 1654 1669
3. D. Cattaneo, N. Perico, and G. Remuzzi From pharmacokinetics to pharmacogenomics: a new approach to tailor immunosuppressive therapy Am. J. Transplant. 4 2004 299 310
4. F. Gaspari, N. Perico, R. Pisoni, M.F. Anedda, O. Signorini, and R. Caruso How to convert from traditional cyclosporine to the microemulsion formulation in stable renal transplant patients? Clin. Transplant. 12 5 1998 Oct 379 390
5. F. Gaspari, R. Caruso, D. Cattaneo, N. Perico, and G. Remuzzi Optimization of cyclosporine therapy in the neoral era: abbreviated AUC, single blood sampling? Transplant. Proc. 33 2001 3117 3119
6. 2 monitoring in clinical practice Transplantation 73 2002 S19 S22
7. B.D. Kahan, L.M. Shaw, D. Holt, J. Grevel, and A. Johnston Consensus document: Hawk's Cay meeting on therapeutic drug monitoring of cyclosporine Clin. Chem. 36 1990 1510 1516
8. W. Steimer Performance and specificity of monoclonal immunoassays for cyclosporine monitoring: how specific is specific? Clin. Chem. 45 1999 371 381
9. S.J. Soldin, B.W. Steele, D.L. Witte, E. Wang, and R.J. Elin Lack of specificity of cyclosporine immunoassays. Results of a College of American Pathologists Study Arch. Pathol. Lab. Med. 127 2003 19 22
10. M. Oellerich, V.W. Armstrong, B. Kahan, L. Shaw, D.W. Holt, and R. Yatscoff Lake Louis Consensus Conference on cyclosporin monitoring in organ transplantation: report of the consensus panel Ther. Drug Monit. 17 6 1995 Dec 642 654 [Review, No abstract available]
11. N. Perico, P. Ruggenenti, F. Gaspari, L. Mosconi, A. Benigni, and C.S. Amuchastegui Daily renal hypoperfusion induced by cyclosporine in patients with renal transplantation Transplantation 54 1 1992 Jul 56 60
12. F. Gaspari, M.F. Anedda, O. Signorini, G. Remuzzi, and N. Perico Prediction of cyclosporine area under the curve using a three-point sampling strategy after Neoral administration J. Am. Soc. Nephrol. 8 1997 647 652
13. D. Cattaneo, F. Gaspari, S. Zenoni, S. Baldelli, E. Gotti, and A. Perna Two-hour post-dose cyclosporine monitoring does not fit all in kidney transplantation Therapy 2 1 2005 95 105
14. International Cyclosporin Proficiency Testing Scheme. WWW bioanalytics co uk 2003.
15. D.W. Holt, K. Jones, T. Lee, P. Stadler, and A. Johnston Quality assessment issues of new immunosuppressive drugs and experimental experience Ther. Drug Monit. 18 1996 362 367
16. D.W. Holt, and A. Johnston Monitoring new immunosuppressive agents. Are methods adequate? Drug Metabol. Drug Interact. 14 1997 5 15
17. H. Passing, and W. Bablock A new biometric procedure for testing the equality of measurements from two different methods J. Clin. Chem. Clin. Biochem. 19 1981 121 137
18. G.C. Kahn, M.S. Leslie, and M.D. Kane Routine monitoring of cyclosporine in whole blood and in kidney tissue using high performance liquid chromatography J. Anal. Toxicol. 10 1986 28 34
19. C.S. Van Dobben de Bruyn K. Griffin Cumulative sum tests: theory and practice 1968 Statistics London 1 45
20. J.M. Bland, and D.G. Altman Statistical methods for assessing agreement between two methods of clinical measurements Lancet 1 1986 307 310
21. K. Dewitte, C. Fierens, D. Stockl, and L.M. Thienpont Application of the Bland-Altman plot for interpretation of method-comparison studies: a critical investigation of its practice Clin. Chem. 48 2002 799 801
22. M.H. Beresini, D. Davalian, S. Alexander, R. Toton-Quinn, B. Barnett, and M.J. Cerelli Evaluation of EMIT cyclosporine assay for use with whole blood Clin. Chem. 39 11 Pt 1 1993 Nov 2235 2241
23. G. Schumann, D. Petersen, P.F. Hoyer, and K. Wonigeit Monitoring cyclosporin A (cyclosporin, INN) concentrations in whole blood: evaluation of EMIT assay in comparison with HPLC and RIA Eur. J. Clin. Chem. Clin. Biochem. 31 1993 381 388
24. E. Schutz, D. Svinarov, M. Shipkova, P.D. Niedmann, V.W. Armstrong, and E. Wieland Cyclosporin whole blood immunoassays (AxSYM, CEDIA, and Emit): a critical overview of performance charactristics and comparison with HPLC Clin. Chem. 44 10 1998 Oct 2158 2164
25. A. Hamwi, A. Salomon, R. Steinbrugger, M. Fritzer-Szekeres, W. Jager, and T. Szekeres Cyclosporine metabolism in patient after kidney, bone marrow, heart-lung, and liver transplantation in the early and late posttransplant periods Am. J. Clin. Pathol. 114 2000 536 543
26. A. Johnston, G. Chusney, E. Schutz, M. Oellerich, T.D. Lee, and D.W. Holt Monitoring cyclosporin in blood: between-assay differences at trough and 2 hours post-dose (C2) Ther. Drug Monit. 25 2003 167 173
27. A.R. Terrel, T.M. Daly, K.G. Hock, D.C. Kilgore, T.Q. Wei, and S. Hernandez Evaluation of a no-pretreatment cyclosporin A assay on the Dade Behring Dimension RxL clinical chemistry analyzer Clin. Chem. 48 7 2002 Jul 1059 1065
28. 2 levels? Ther. Drug Monit. 23 2001 A471
29. P.E. Wallemacq Therapeutic monitoring of immunosuppressant drugs. Where are we? Clin. Chem. Lab. Med. 42 2004 1204 1211
30. A. Johnston, and D.W. Holt Immunosuppressant drugs-the role of therapeutic drug monitoring Br. J. Clin. Pharmacol. 52 Suppl. 1 2001 61S 73S