1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 4, 2005, Pages 1217-1220

  Wattanasin, Sompong ^a   Kallen, Joerg ^b   Myers, Stewart ^a   Guo, Qin ^a   Sabio, Michael ^a   Ehrhardt, Claus ^b   Albert, Rainer ^b   Hommel, Ulrich ^b   Weckbecker, Gisbert ^b   Welzenbach, Karl ^b   Weitz Schmidt, Gabriele ^b  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Diazepanediones; I domain; Integrin; L site binding; LFA 1

Indexed keywords

LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; PIPERAZINE DERIVATIVE; RECEPTOR BLOCKING AGENT;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INHIBITION KINETICS; STRUCTURE ACTIVITY RELATION;

EID: 20144387488     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.11.072     Document Type: Article

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