Organophosphorus compound DEPBT as a coupling reagent for oligopeptides and peptoids synthesis: Studies on its mechanism

Chinese Chemical Letters

Volumn 13, Issue 7, 2002, Pages 601-604

  Liu, Hui ^a   Xia, Lin ^a   Ye, Yun Hua ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

Amino acids; Coupling; Peptides; Phosphorus

Indexed keywords

BIOTIN; OLIGOPEPTIDE; ORGANOPHOSPHORUS COMPOUND; PEPTOID; REAGENT;

ARTICLE; CHEMICAL BOND; PEPTIDE SYNTHESIS; REACTION ANALYSIS; SYNTHESIS;

EID: 20144375197     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. C. X. Fan, X. L. Hao, Y. H. Ye, Synthetic Commun. 1996, 26 (7), 1455.
2. Y. H. Ye, C. X. Fan, D. Y. Zhang, et al, Chem. J. Chin. Univ. 1997, 7 (in Chinese), 1086.
3. Standard abbreviation for amino acids and protecting groups follow the IUPAC-IUB Joint Commission on Biochemistry Nomenclature J. Biol. Chem. 1971, 247, 977.
4. H. T. Li, Racemization Studies on a New Coupling Reagent 3-(Diethoxy- phosphoryloxy)-1,2,3 benzotrazin-4(3H)-one (DEPBT). (Unpublished data)
5. G. R. Pettit, "Synthetic Peptides", Vol. 1-6, 1970, 1971, 1975, 1976, 1980, 1982, Van Nostrand Rainhold Co. N.Y.
6. +), 91 (base peak).