Expanded FMR1 alleles are rare in idiopathic Parkinson's disease [3]

Neurogenetics

Volumn 6, Issue 1, 2005, Pages 51-52

  Tan, E K ^a,b,c   Zhao, Y ^a   Puong, K Y ^a   Law, H Y ^d   Chan, L L ^a   Yew, K ^a   Shen, H ^a   Chandran, V R ^a   Yuen, Y ^a   Pavanni, R ^a,b   Wong, M C ^a,b   Ng, I S ^d  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

^b National Neuroscience Institute   (Singapore)

^c Singapore Health Services   (Singapore)

^d KK WOMEN'S AND CHILDREN'S HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN;

ADULT; AGED; ALLELE; ATAXIA; CLINICAL FEATURE; DNA EXTRACTION; FEMALE; FRAGILE X SYNDROME; GENE MUTATION; HUMAN; LETTER; MAJOR CLINICAL STUDY; MALE; PARKINSON DISEASE; PARKINSONISM; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TREMOR;

ADULT; AGE OF ONSET; AGED; FRAGILE X MENTAL RETARDATION PROTEIN; HUMANS; MIDDLE AGED; NERVE TISSUE PROTEINS; PARKINSON DISEASE; RNA-BINDING PROTEINS;

ATAXIA;

EID: 20144372912     PISSN: 13646745     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10048-004-0200-5     Document Type: Letter

References (6)

1. Hagerman RJ, Leehey M, Heinrichs W, et al (2001) Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X. Neurology 57:127-130
2. Jacquemont S, Hagerman RJ, Leehey M, et al (2003) Fragile X premutation tremor/ataxia syndrome: molecular, clinical, and neuroimaging correlates. Am J Hum Genet 72:869-878
3. Tassone F, Hagerman RJ, Taylor AK, et al (2000) Elevated levels of FMR1 mRNA in carrier males: a new mechanism of involvement in fragile X syndrome. Am J Hum Genet 66:6-15
4. Leehey, Zhang L, Wheelock V, Tassone F, Hagerman R, Hagerman PJ (2004) A preliminary observation: increased frequency of fragile X expanded alleles in patients that meet the diagnostic criteria for MSA. Mov Disord 19: [Suppl 9]:S339
5. Tan EK, Zhao Y, Puong KY, et al (2004) Fragile X premutation alleles in SCA, ET, and parkinsonism in an Asian cohort. Neurology 63:362-363
6. Leehey E, Berry-Kravis E, Jacquemont, Zhang L, Hagerman R, Hagerman PJ (2004) Misdiagnosis of fragile X associated tremor/ataxia syndrome (FXTAS). Mov Disord 19 [Suppl 9]:S338