Clinical effects of strontium ranelate in women with postmenopausal osteoporosis

Osteoporosis International

Volumn 16, Issue SUPPL. 1, 2005, Pages

  Delmas, Pierre D ^a  

^a EDOUARD HERRIOT HOSPITAL   (France)

Author keywords

Bone mineral density (BMD); Osteoporosis; Strontium ranelate; Vertebral fractures

Indexed keywords

CALCIUM; PLACEBO; STRONTIUM RANELATE; VITAMIN D;

BACKACHE; BODY HEIGHT; CLINICAL TRIAL; DIARRHEA; DISSOCIATION; DRUG EFFECT; DRUG EFFICACY; DRUG TOLERABILITY; ESOPHAGITIS; FEMALE; FRAGILITY FRACTURE; GASTRITIS; HUMAN; INCIDENCE; OSSIFICATION; OSTEOLYSIS; POSTMENOPAUSE OSTEOPOROSIS; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; RISK REDUCTION; STOMACH ULCER; VERTEBRA FRACTURE;

AGED; CLINICAL TRIALS, PHASE III; DIARRHEA; FEMALE; FRACTURES, BONE; GASTRITIS; HUMANS; MIDDLE AGED; ORGANOMETALLIC COMPOUNDS; OSTEOPOROSIS, POSTMENOPAUSAL; QUALITY OF LIFE; RISK; SPINAL FRACTURES; THIOPHENES; UNCOUPLING AGENTS;

EID: 20044391634     PISSN: 0937941X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00198-004-1767-2     Document Type: Review

References (18)

1. O'Neill TW, Roy DK (2003) The epidemiology and scale of the problem. Hosp Med 64(9):517-520
2. Truumees E (2003) Medical consequences of osteoporotic vertebral compression fractures. Instr Course Lect 52:551-558
3. Hawker GA (1996) The epidemiology of osteoporosis. J Rheumatol Suppl 45:2-5
4. Gold DT (2003) Osteoporosis and quality of life psychosocial outcomes and interventions for individual patients. Clin Geriatr Med 19(2):271-280
5. Martin AR, Sornay-Rendu E, Chandler JM, Duboeuf F, Girman CJ, Delmas PD (2002) The impact of osteoporosis on quality-of-life: the OFELY cohort. Bone 31:32-36
6. Marie PJ, Ammann P, Boivin G, Rey C (2001) Mechanisms of action and therapeutic potential of strontium in bone. Calcif Tissue Int 69:121-129
7. Reginster JY (2002) Strontium ranelate in osteoporosis. Curr Pharm Des 8:1907-1916
8. Reginster JY, Deroisy R, Jupsin I (2003) Strontium ranelate: a new paradigm in the treatment of osteoporosis. Drugs Today (Barc) 39:89-101
9. Meunier PJ, Reginster JY (2003) Design and methodology of the phase III trials for the clinical development of strontium ranelate in the treatment of women with postmenopausal osteoporosis. Osteoporos Int 14[Suppl 3]:S66-S76
10. Meunier PJ, Roux C, Seeman E, Ortolani S, Badurski JE, Spector TD, Cannata J, Balogh A, Lemmel EM, Pors-Nielsen S, Rizzoli R, Genant HK, Reginster JY (2004) The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med 350:459-68
11. Silverman SL, Minshall ME, Shen W, Harper KD, Xie S (2001) The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis: results from the Multiple Outcomes of Raloxifene Evaluation Study. Health-Related Quality of Life Subgroup of the Multiple Outcomes of Raloxifene Evaluation Study. Arthritis Rheum 44:2611-2619
12. Oleksik A, Lips P, Dawson A, Minshall ME, Shen W, Cooper C, Kanis J (2000) Health-related quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res 15:1384-1392
13. Randell AG, Nguyen TV, Bhalerao N, Silverman SL, Sambrook PN, Eisman JA (2000) Deterioration in quality of life following hip fracture: a prospective study. Osteoporos Int 11:460-466
14. Cohen-Solal ME, de Vernejoul MC (2002) Quality of life in osteoporosis. Medicographia 24:349-352
15. Osteoporosis Quality of Life Study Group (1997) Measuring quality of life in women with osteoporosis. Osteoporos Int 7:478-487
16. Helmes E, Hodsman A, Lazowski D, Bhardwaj A, Crilly R, Nichol P, Drost D, Vanderburgh L, Pederson L (1995) A questionnaire to evaluate disability in osteoporotic patients with vertebral compression fractures. J Gerontol A Biol Sci Med Sci 50:M91-M98
17. Marquis P, Cialdella P, De la Loge C (2001) Development and validation of a specific quality of life module in post-menopausal women with osteoporosis: the QUALIOST. Qual Life Res 10:555-566
18. Tosteson AN, Hammond CS (2002). Quality-of-life assessment in osteoporosis: health-status and preference-based measures. Pharmacoeconomics 20:289-303