Cloning and expression of a novel isoform of heterogeneous nuclear ribonucleoprotein-R

NeuroReport

Volumn 16, Issue 7, 2005, Pages 727-730

  Huang, Jia ^a   Chen, Xian Hua ^a   Wu, Kun ^a   Xu, Ping ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Expression; Heterogeneous nuclear ribonucleoprotein R isoforms; Neural development

Indexed keywords

HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R2; HETEROGENEOUS NUCLEAR RNA; ISOPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN DEVELOPMENT; EXON; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE SPECIFICITY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BRAIN; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; COS CELLS; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; HELA CELLS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN ISOFORMS; RNA PRECURSORS;

EID: 20044384396     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200505120-00014     Document Type: Article

References (20)

1. Kredo AM, Swanson MS. hnRNP complexes: composition, structure, and function. Curr Opin Cell Biol 1999; 11:363-371.
2. Ostrowski J, Kawata Y, Schullery DS, Denisenko ON, Higaki Y, Abrass CK et al. Insulin alters heterogeneous nuclear ribonucleoprotein K protein binding to DNA and RNA. Proc Natl Acad Sci USA 2001; 98:9044-9049.
3. Chou MY, Rooke N, Turck CW, Black DL. hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells. Mol Cell Biol 1999; 19:69-77.
4. Rajagopalan LE, Westmark CJ, Jarzembowski JA, Malter JS. hnRNP C increases amyloid precursor protein (APP) production by stabilizing APP mRNA. Nucleic Acids Res 1998; 26:3418-3423.
5. Liu J, Beqaj S, Yang Y, Honore B, Schuger L. Heterogeneous nuclear ribonucleoprotein-H plays a suppressive role in visceral myogenesis. Mech Dev 2001; 104:79-87.
6. Hassfeld W, Chan EK, Mathison DA, Portman D, Dreyruss G, Steiner G et al. Molecular definition of heterogeneous nuclear ribonucleoprotein R (hnRNP R) using autoimmune antibody: immunological relationship with hnRNP P. Nucleic Acids Res 1998; 26:439-445.
7. Rossoll W, Kroning AK, Ohndorf UM, Steegborn C, Jablonka S, Sendtner M. Specific interaction of SMN, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons? Hum Mol Genet 2002; 11:93-105.
8. Mourelatos Z, Abel L, Yong J, Kataoka N, Dreyfuss G. SMN interacts with a novel family of hnRNP and spliceosomal proteins. EMBO J 2001; 20:5443-5452.
9. Rossoll W, Kroning AK, Ohndorf UM, Steegborn C, Jablonka S, Sendtner M. SMN, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of β-actin mRNA in growth cones of motoneurons. J Cell Biol 2003; 163:801-812.
10. Xu P, La Vallee P, Hoidal JR. Repressed expression of the human xanthine oxidoreductase gene E-box and TATA-like elements restrict ground state transcriptional activity. J Biol Chem 2000; 275:5918-5926.
11. Hortsch M. Mol Cell Structural and functional evolution of the L1 family: are four adhesion molecules better than one? Neurosci 2000; 15:1-10.
12. Liu L, Lin JJ, Chen X, Liu X, Xu P. Neural expression and regulation of NSSR1 proteins. Neuroreport 2003; 14:1847-1850.
13. Chen XH, Guo LP, Lin WM, Xu P. Expression of Tra2 beta isoforms is developmentally regulated in a tissue- and temporal-specific pattern. Cell Biol Int 2003; 27:491-496.
14. Modrek B, Resch A, Grasso C, Lee C. Genome-wide detection of alternative splicing in expressed sequences of human genes. Nucleic Acids Res 2001; 29:2850-2859.
15. Lall S, Francis-Lang H, Flament A, Norvell A, Schupbach T, Ish-Horowicz D. Squid hnRNP protein promotes apical cytoplasmic transport and localization of Drosophila pair-rule transcripts. Cell 1999; 98:171-180.
16. Seigel GM, Sun W, Wang J, Hershberger DH, Campbell LM, Salvi RJ. Neuronal gene expression and function in the growth-stimulated R28 retinal precursor cell line. Curr Eye Res 2004; 28:257-269.
17. Wang J, Manley JL. Regulation of pre-mRNA splicing in metazoa. Curr Opin Genet Develop 1997; 7:205-211.
18. Colwill K, Pawson T, Andrews B, Prasad J, Manley JL, Bell JC et al. The C1k/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution. EMBO J 1996; 15:265-275.
19. Nayler O, Cap C, Stamm S. Human transformer-2-beta gene (SFRS10): complete nucleotide sequence, chromosomal localization, and generation of a tissue-specific isoform. Genomics 1998; 53:191-202.
20. Xu NH, Chen CY, Shyu AB. Versatile role for hnRNP D isoforms in the differential regulation of cytoplasmic mRNA turnover. Mol Cell Biol 2001; 21:6960-6971.