Intravenous delivery of liposome-mediated nonviral DNA is less toxic than intraperitoneal delivery in mice

World Journal of Surgery

Volumn 29, Issue 3, 2005, Pages 339-343

  Wang, X P ^a   Yazawa, K ^a   Templeton, N S ^a   Yang, J ^a   Liu, Shihe ^a   Li, Zhijun ^a   Li, M ^a   Yao, Q ^a   Chen, C ^a   Brunicardi, F C ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EOSIN; GANCICLOVIR; GLUCAGON; GLUCOSE; HEMATOXYLIN; INSULIN; LIPOSOME; LIVER ENZYME; THYMIDINE KINASE; VIRUS DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AUTOPSY; CELL SPECIFICITY; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; LIVER INJURY; MORPHOLOGY; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PANCREAS ISLET CELL; PROMOTER REGION; SCID MOUSE; SUICIDE GENE;

ANIMALS; CELL SURVIVAL; FEMALE; GENE THERAPY; HOMEODOMAIN PROTEINS; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; ISLETS OF LANGERHANS; LIPOSOMES; LIVER; MICE; MICE, SCID; PANCREATIC NEOPLASMS; THYMIDINE KINASE; TRANS-ACTIVATORS;

EID: 20044378692     PISSN: 03642313     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00268-004-7822-5     Document Type: Conference Paper

References (22)

1. GG Ginsberg 2000 New developments in pancreatic cancer, Semin Gastrointest. Dis. 11 162 167
2. MF Brennan 2000 Pancreatic cancer J. Gastroenterol. Hepatol. 15 G13 G16
3. Yeo, CJ, Cameron, JL (1997) In: Sabiston, Dc, Lyerly, Hk (editors), Neoplasms of the Pancreas Exocrine Tumors, 5, W.B. Saunders Company, Philadelphia
4. K Aoki T Yoshida N Matsumoto 1997 Gene therapy for peritoneal dissemination of pancreatic cancer by liposome-mediated transfer of herpes simplex virus thymidine kinase gene Hum. Gene Ther. 8 1105 1113
5. H Kanyama N Tomita T Yamono 2001 Usefulness of repeated direct intratumoral gene transfer using hemagglutinating virus of Japan-liposome method for cytosine deaminase suicide gene therapy Cancer Res. 61 14 18
6. RM Schmid H Weidenbach H Yamagushi 1998 Direct gene transfer into the rat pancreas using DNA-liposomes Eur. J. Clin. Invest. 28 220 226
7. NS Templeton DD Lasic PM Frederik 1997 Improved DNA: liposome complexes for increased systemic delivery and gene expression Nat. Biotech. 15 647 652
8. Y Zhang H Lu P Li Wang 2003 Optimization of gene expression in nonactivated circulating lymphocytes Mol. Ther. 8 629 636
9. R Ramesh T Saeke NS Templeton 2001 Successful treatment of primary and disseminated human lung cancers by systemic delivery of tumor suppressor genes using an improved liposome vector Mol. Ther. 3 337 350
10. TA Tirone SP Fagan NS Templeton 2001 Insulinoma-induced hypoglycemic death in mice is prevented with beta cell-specific gene therapy Ann. Surg. 233 603 611
11. Tirone TA, Wang XP, Templeton NS, et al. Cell-specific cytotoxicity of human pancreatic adenocarcinoma cells using rat insulin promoter thymidine kinase directed gene therapy. World. J. Surg. 2004; 28: 826-833
12. FD Ledley 1993 Hepatic gene therapy: present and future Hepatology 18 1263 1273
13. L Blaszkowsky 1998 Treatment of advanced and metastatic pancreatic cancer Front. Biosci. 3 214 225
14. P McMahon E Halpern C Fernandez-del Castillo 2001 Pancreatic cancer: cost-effectiveness of imaging technologies for assessing resectability Radiology 221 93 106
15. N Zhu D Liggitt Y Liu 1993 Systemic gene expression after intravenous DNA delivery into adult mice Science 261 209 211
16. Y Liu D Liggitt Zhong 1995 Cationic liposome-mediated intravenous gene delivery J. Biol. Chem. 270 24864 24870
17. SW Dow RE Elmslie AP Willson 1998 In vivo tumor transfection with superantigen plus cytokine genes induces tumor regression and prolongs survival in dogs with malignant melanoma J. Clin. Invest. 101 2406 2414
18. WM Siders K Vergillis C Johnson 2002 Tumor treatment with complexes of cationic lipid and noncoding plasmid DNA results in the induction of cytotoxic T cells and systemic tumor elimination Mol. Then 6 519 527
19. L Mohr SK Yoon SJ Eastman 2001 Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice Hum Gene Ther. 12 799 809
20. P Bankey E Beecherl E Bibus 1995 Liposomes modulate Kupffer cell endotoxin response Arch. Surg. 130 1266 1272
21. M Shichiri A Tanaka Y Hirata 2003 Intravenous gene therapy for familial hypercholesterolemia using ligand-facilitated transfer of liposome:LDL receptor gene complexes Gene Ther. 10 827 831
22. J Norman W Denham D Denham 2000 Liposome-mediated, nonviral gene transfer induces a systemic inflammatory response which can exacerbate pre-existing inflammation Gene Ther. 7 1425 1430