Posttraumatic stress disorder comorbid with major depression: Factors mediating the association with suicidal behavior

American Journal of Psychiatry

Volumn 162, Issue 3, 2005, Pages 560-566

  Oquendo, Maria ^a   Brent, David A ^b   Birmaher, Boris ^b   Greenhill, Laurence ^b   Kolko, David ^b   Stanley, Barbara ^b   Zelazny, Jamie ^b   Burke, Ainsley K ^b   Firinciogullari, Sekip ^b   Ellis, Steven P ^b   Mann, J John ^b  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ANAMNESIS; ARTICLE; COMORBIDITY; CONTROLLED STUDY; FEMALE; HOSTILITY; HUMAN; IMPULSIVENESS; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MULTIPLE REGRESSION; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; RISK ASSESSMENT; RISK FACTOR; SUICIDAL BEHAVIOR;

ADULT; AGED; AGGRESSION; CHILD; CHILD ABUSE; CHILD ABUSE, SEXUAL; COMORBIDITY; DEPRESSIVE DISORDER, MAJOR; HOSTILITY; HUMANS; LIFE CHANGE EVENTS; MIDDLE AGED; MULTIVARIATE ANALYSIS; PERSONALITY DISORDERS; PERSONALITY INVENTORY; PSYCHIATRIC STATUS RATING SCALES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; STRESS DISORDERS, POST-TRAUMATIC; SUICIDE; SUICIDE, ATTEMPTED;

EID: 20044371603     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.162.3.560     Document Type: Article

References (55)

1. Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, Wittchen H-U, Kendler KS: Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States: results from the National Comorbidity Survey. Arch Gen Psychiatry 1994; 51:8-19
2. Kessler RC, Sonnega A, Bromet E, Hughes M, Nelson CB: Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry 1995; 52:1048-1060
3. Breslau N: The epidemiology of posttraumatic stress disorder: what is the extent of the problem? J Clin Psychiatry 2001; 62(suppl 17):16-22
4. Green BL, Lindy JD, Grace MC, Gleser GC, Leonard AC, Korol M, Winget C: Buffalo Creek survivors in the second decade: stability of stress symptoms. Am J Orthopsychiatry 1990; 60:43-54
5. Kramer TL, Lindy JD, Green BL, Grace MC, Leonard AC: The comorbidity of post-traumatic stress disorder and suicidality in Vietnam veterans. Suicide Life Threat Behav 1994; 24:58-67
6. Maes M, Mylle J, Delmeire L, Altamura C: Psychiatric morbidity and comorbidity following accidental man-made traumatic events: incidence and risk factors. Eur Arch Psychiatry Clin Neurosci 2000; 250:156-162
7. North CS, Nixon SJ, Shariat S, Mallonee S, McMillen JC, Spitznagel EL, Smith EM: Psychiatric disorders among survivors of the Oklahoma City bombing. JAMA 1999; 282:755-762
8. Fullerton CS, Ursano RJ, Epstein RS, Crowley B, Vance KL, Kao TC, Baum A: Peritraumatic dissociation following motor vehicle accidents: relationship to prior trauma and prior major depression. J Nerv Ment Dis 2000; 188:267-272
9. Breslau N, Davis GC, Peterson EL, Schultz L: Psychiatric sequelae of posttraumatic stress disorder in women. Arch Gen Psychiatry 1997; 54:81-87
10. Kendler KS, Walters EE, Neale MC, Kessler RC, Heath AC, Eaves LJ: The structure of the genetic and environmental risk factors for six major psychiatric disorders in women: phobia, generalized anxiety disorder, panic disorder, bulimia, major depression, and alcoholism. Arch Gen Psychiatry 1995; 52:374-383
11. Chen YW, Dilsaver SC: Lifetime rates of suicide attempts among subjects with bipolar and unipolar disorders relative to subjects with other Axis I disorders. Biol Psychiatry 1996; 39:896-899
12. Davidson JR, Hughes D, Blazer DG, George LK: Post-traumatic stress disorder in the community: an epidemiological study. Psychol Med 1991; 21:713-721
13. Pollock DA, Rhodes P Boyle CA, Decoufle P, McGee DL: Estimating the number of suicides among Vietnam veterans. Am J Psychiatry 1990; 147:772-776
14. Hyer L, McCranie EW, Woods MG, Boudewyns PA: Suicidal behavior among chronic Vietnam theatre veterans with PTSD. J Clin Psychol 1990; 46:713-721
15. Hendin H, Haas AP: Suicide and guilt as manifestations of PTSD in Vietnam combat veterans. Am J Psychiatry 1991; 148:586-591
16. Freeman TW, Roca V, Moore WM: A comparison of chronic combat-related posttraumatic stress disorder (PTSD) patients with and without a history of suicide attempt. J Nerv Ment Dis 2000; 188:460-463
17. Oquendo MA, Friend JM, Halberstam B, Brodsky BS, Burke AK, Grunebaum MF, Malone KM, Mann JJ: Association of comorbid posttraumatic stress disorder and major depression with greater risk for suicidal behavior. Am J Psychiatry 2003; 160: 580-582
18. Marshall RD, Olfson M, Hellman F, Blanco C, Guardino M, Struening EL: Comorbidity, impairment, and suicidality in subthreshold PTSD. Am J Psychiatry 2001; 158:1467-1473
19. Shalev AY, Freedman S, Peri T, Brandes D, Sahar T, Orr SP, Pitman RK: Prospective study of posttraumatic stress disorder and depression following trauma. Am J Psychiatry 1998; 155: 630-637
20. Widom CS: Posttraumatic stress disorder in abused and neglected children grown up. Am J Psychiatry 1999; 156:1223-1229
21. MacMillan HL, Fleming JE, Streiner DL, Lin E, Boyle MH, Jamieson E, Duku EK, Walsh CA, Wong MY-Y, Beardslee WR: Childhood abuse and lifetime psychopathology in a community sample. Am J Psychiatry 2001; 158:1878-1883
22. van der Kolk BA, Perry JC, Herman JL: Childhood origins of self-destructive behavior. Am J Psychiatry 1991; 148:1665-1671
23. Linehan MM: Suicidal people: one population or two? Ann NY Acad Sci 1986; 487:16-33
24. Soloff PH, Lynch KG, Kelly TM: Childhood abuse as a risk factor for suicidal behavior in borderline personality disorder. J Personal Disord 2002; 16:201-214
25. Mehlum L, Friis S, Vaglum P, Karterud S: The longitudinal pattern of suicidal behaviour in borderline personality disorder, a prospective follow-up study. Acta Psychiatr Scand 1994; 90: 124-130
26. Gunderson JG, Sabo AN: The phenomenological and conceptual interface between borderline personality disorder and PTSD. Am J Psychiatry 1993; 150:19-27
27. Skodol AE, Stout RL, McGlashan TH, Grilo CM, Gunderson JG, Shea MT, Morey LC, Zanarini MC, Dyck IR, Oldham JM: Co-occurrence of mood and personality disorders: a report from the Collaborative Longitudinal Personality Disorders Study (CLPS). Depress Anxiety 1999; 10:175-182
28. Spitzer RL, Williams JBW, Gibbon M, First MB: Structured Clinical Interview for DSM-IV (SCID). New York, New York State Psychiatric Institute, Biometrics Research, 1995
29. Hamilton M: A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62
30. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J: An inventory for measuring depression. Arch Gen Psychiatry 1961; 4: 561-571{checked}
31. Oquendo MA, Halberstam B, Mann JJ: Risk factors for suicidal behavior: the utility and limitations of research instruments, in Standardized Evaluation in Clinical Practice. Edited by First MB. Washington, DC, American Psychiatric Publishing, 2003, pp 103-131
32. Beck AT, Beck R, Kovacs M: Classification of suicidal behaviors, I: quantifying intent and medical lethality. Am J Psychiatry 1975; 132:285-287
33. Beck AT, Kovacs M, Weissman A: Assessment of suicidal intention: the Scale for Suicide Ideation. J Consult Clin Psychol 1979; 47:343-352
34. Beck AT, Weissman A, Lester D, Trexler L: The measurement of pessimism: the Hopelessness Scale. J Consult Clin Psychol 1974; 42:861-865
35. Brown GL, Goodwin FK, Ballenger JC, Goyer PF, Major LF: Aggression in humans correlates with cerebrospinal fluid amine metabolites. Psychiatry Res 1979; 1:131-139
36. Buss AH, Durkee A: An inventory for assessing different kinds of hostility. J Consult Psychol 1957; 21:343-349
37. Barratt ES: Factor analysis of some psychometric measures of impulsiveness and anxiety. Psychol Rep 1965; 16:547-554
38. First MB, Spitzer RL, Gibbon M, Williams JBW, Benjamin L: Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II), Version 2.0. New York, New York State Psychiatric Institute, Biometrics Research, 1996
39. Golier JA, Yehuda R, Bierer LM, Mitropoulou V, New AS, Schmeidler J, Silverman JM, Siever LJ: The relationship of borderline personality disorder to posttraumatic stress disorder and traumatic events. Am J Psychiatry 2003; 160:2018-2024
40. Soloff PH, Lis JA, Kelly T, Cornelius J, Ulrich R: Risk factors for suicidal behavior in borderline personality disorder. Am J Psychiatry 1994; 151:1316-1323
41. Mann JJ, Waternaux C, Haas GL, Malone KM: Toward a clinical model of suicidal behavior in psychiatric patients. Am J Psychiatry 1999; 156:181-189
42. Kotler M, Iancu I, Efroni R, Amir M: Anger, impulsivity, social support, and suicide risk in patients with posttraumatic stress disorder. J Nerv Ment Dis 2001; 189:162-167
43. Begic D, Jokic-Begic N: Aggressive behavior in combat veterans with post-traumatic stress disorder. Mil Med 2001; 166:671-676
44. McFall M, Fontana A, Raskind M, Rosenheck R: Analysis of violent behavior in Vietnam combat veteran psychiatric inpatients with posttraumatic stress disorder. J Trauma Stress 1999; 12:501-517
45. Brodsky BS, Mann JJ: Risk factors for suicidal behavior in borderline personality disorder. J Calif Alliance Ment III 1997; 8: 27-28
46. Brent DA, Oquendo M, Birmaher B, Greenhill L, Kolko D, Stanley B, Zelazny J, Brodsky B, Bridge J, Ellis S, Salazar JO, Mann JJ: Familial pathways to early-onset suicide attempt: risk for suicidal behavior in offspring of mood-disordered suicide attempters. Arch Gen Psychiatry 2002; 59:801-807
47. Boudewyn AC, Liem JH: Childhood sexual abuse as a precursor to depression and self-destructive behavior in adulthood. J Trauma Stress 1995; 8:445-459
48. Heim C, Nemeroff CB: The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biol Psychiatry 2001; 49:1023-1039
49. Herman JL, van der Kolk BA: Traumatic antecedents of borderline personality disorder, in Psychological Trauma. Edited by van der Kolk BA. Washington, DC, American Psychiatric Press, 1987, pp 111-126
50. Zanarini MC, Frankenburg FR, Dubo ED, Sickel AE, Trikha A, Levin A, Reynolds V: Axis I comorbidity of borderline personality disorder. Am J Psychiatry 1998; 155:1733-1739
51. Zlotnick C, Johnson DM, Yen S, Battle CL, Sanislow CA, Skodol AE, Grilo CM, McGlashan TH, Gunderson JG, Bender DS, Zanarini MC, Shea MT: Clinical features and impairment in women with Borderline Personality Disorder (BPD) with Posttraumatic Stress Disorder (PTSD), BPD without PTSD, and other personality disorders with PTSD. J Nerv Ment Dis 2003; 191: 706-713
52. Kjellander C, Bongar B, King A: Suicidality in borderline personality disorder. Crisis 1998; 19:125-135
53. Soloff PH, Lynch KG, Kelly TM, Malone KM, Mann JJ: Characteristics of suicide attempts of patients with major depressive episode and borderline personality disorder: a comparative study. Am J Psychiatry 2000; 157:601-608
54. Corbitt EM, Malone KM, Haas GL, Mann JJ: Suicidal behavior in patients with major depression and comorbid personality disorders. J Affect Disord 1996; 39:61-72
55. Heffernan K, Cloitre M: A comparison of posttraumatic stress disorder with and without borderline personality disorder among women with a history of childhood sexual abuse: etiological and clinical characteristics. J Nerv Ment Dis 2000; 188: 589-595