Bone marrow stromal cells transduced with human hemangiopoietin gene support hematopoiesis in vitro

Haematologica

Volumn 90, Issue 2, 2005, Pages 157-165

  Xu, Zhen Shu ^a,b   Liu, Yong Jun ^a   Lv, Lu Lu ^a,b   Han, Zhi Bo ^a   He, Rui ^a   Lu, Shi Hong ^a   Wang, Tong ^a   Xu, Bin ^a   Chen, Zhi Zhe ^b   Han, Zhong Chao ^a  

^a INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Bone marrow stromal cell; Eukaryotic expression vector; Hemangiopoietin; Hematopoiesis; Stem cells

Indexed keywords

CD34 ANTIGEN; CYTOKINE; GREEN FLUORESCENT PROTEIN; HEMANGIOPOIETIN; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL CULTURE; CELL DIVISION; CELL LINE; CELL TRANSFORMATION; CLONE; CONTROLLED STUDY; EUKARYOTE; EXPRESSION VECTOR; GENE; GENE EXPRESSION; GENE SEQUENCE; GENE TARGETING; GENETIC TRANSFECTION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROSCOPY; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; WESTERN BLOTTING;

ANGIOPOIETINS; ANIMALS; ANTIGENS, CD34; BLOTTING, WESTERN; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL LINE; COCULTURE TECHNIQUES; GREEN FLUORESCENT PROTEINS; HEMATOPOIESIS; HUMANS; MICE; POLYMERASE CHAIN REACTION; PROTEOGLYCANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELLS; STROMAL CELLS;

EID: 20044369917     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Duhrsen U, Hossfeld DK. Stromal abnormalities in neoplastic bone marrow diseases. Ann Hematol 1996; 73: 53-70.
2. Schwartz GN, Kessler SW, Rothwell SW, Burrell LM, Reid TF, Meltzer MS, et al. Inhibitory effects of HIV-1-infected stromal cells layers on the production of myeloid progenitor cells in human long-term bone marrow cultures. Exp Hematol 1994;22:1288-96.
3. Bahner I, Kearns K, Coutinho S, Leonard EH, Kohn DB. Infection of human marrow stroma by human immunodeficiency virus-1 (HIV-1) is both required and sufficient for HIV-1-induced hematopoietic suppression in vitro: demonstration by gene modification of primary human stroma. Blood 1997;90:1787-98.
4. Greenberger JS. Methods for the use of stromal cells for therapeutic gene therapy. In: Robbins PD, ed. Methods in Molecular Medicine, Gene Therapy Protocols. Humana Press: Totowa, NJ; USA. 1997. p. 375-90.
5. Liu YJ, Lu SH, Xu B, Yang RC, Ren Q, Liu B, et al. Hemangiopoietin, a novel human growth factor for the primitive cells or both hematopoietic and endothelial cell lineages. Blood 2004; 103:4449-56.
6. Shimakura Y, Kawada H, Ando K, Sato T, Nakamura Y, Tsuji T, et al. Murine stromal cell line HESS-5 maintains reconstituting ability of ex vivo-generated hematopoietic stem cells from human bone marrow and cytokine-mobilized peripheral blood. Stem Cells 2000;18:183-9.
7. Yin AH, Miraglia S, Zanjani ED, Almeida-Porada G, Ogawa M, Leary AG, et al. A novel marker for human hematopoietic stem and progenitor cells. Blood 1997;90:5002-12.
8. Arock M, Hervatin F, Guillosson JJ, Mencia-Huerta JM, Thierry D. Differentiation of human mast cells from bone marrow and cord blood progenitor cells by factors produced by a mouse stromal cell line. Ann NY Acad Sci 1994;725:59-68.
9. Matsunaga T, Kato T, Miyazaki H, Ogawa M. Thrombopoietin promotes the survival of murine hematopoietic long-term reconstituting cells: comparison with the effects of FLT3/FLK2 ligand and interleukin-6. Blood 1998;92:452-61.
10. Lansdorp PM, Dragowska W. Maintenance or hematopoiesis in serum-free bone marrow cultures involves sequential recruitment of quiescent progenitors. Exp Hematol 1993;21: 1321-7.
11. Young JC, Varma A, DiGiusto D, Backer MP. Retention of quiescent hematopoietic cells with high proliferative potential during ex vivo stem cell culture. Blood 1996;87:545-56.
12. Fauser AA, Messner HA. Granuloerythropoietic colonies in human bone marrow, peripheral blood, and cord blood. Blood 1978;52:1243-8.
13. + subpopulations of human bone marrow cells. Proc Natl Acad Sci USA 1994;91:12223-7.
14. Sutherland HJ, Lansdorp PM, Henkelman DH, Eaves AC, Eaves CJ. Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers. Proc Natl Acad Sci USA 1990;87:3584-8.
15. Sutherland HJ, Eaves CJ, Lansdrop PM, Eaves AC, Eaves CJ, et al. Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells. Blood 1991;78:666-72.
16. Peter AL, Hogge DE, Lansdorp PM, Reid DS, Eaves CJ. Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium. Proc Natl Acad Sci USA 1996;93:1470-4.
17. Micka B, Trojaneck B, Niemitz S, Lefterova P, Kruopis S, Huhn D, et al. Comparison of non-viral transfection methods in melanoma cell primary cultures. Cytokine 2000;20:828-33.
18. Zhan M, Han ZC. Hemangiopoietin inhibits apoptosis of MO7e leukemia cells through phosphatidylinositol 3-kinase-AKT pathway. Biochem Biophys Res Commun 2004;317:198-204.
19. Tsuji T, Ogasawara H, Aoki Y, Tsurumaki Y, Kodama H. Characterization of murine stromal cell clones established from bone marrow and spleen. Leukemia 1996;10:803-12.
20. Petzer AL, Hogge DE, Lansdorp PM, Reid DS, Eaves CJ. Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium. Proc Natl Acad Sci USA 1996;93:1470-4.
21. Bhatia M, Wang JC, Kapp U, Bonnet D, Dick JE. Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice. Proc Natl Acad Sci USA 1997; 94: 5320-5.
22. Zandstra PW, Conneally E, Piret JM, Eaves CJ. Ontogeny-associated changes in the cytokine responses of primitive human hematopoietic cells. Br J Haematol 1998;101:770-8.
23. Traycoff CM, Kosak ST, Grigsby S, Srour EF. Evaluation of ex vivo expansion potential of cord blood and bone marrow hematopoietic progenitor cells using cell tracking and limiting dilution analysis. Blood 1995;85: 2059-68.
24. + hematopoietic progenitor cells mobilized into peripheral blood with high-dose cyclophosphamide and recombinant cytokines increase in vitro following a short exposure to stem cell factor. Exp Hematol 1993;21:1184.
25. Shimakura Y, Kawada H, Ando K, Sato T, Nakamura Y, Tsuji T, et al. Murine stromal cell line HESS-5 maintains reconstituting ability of ex vivo-generated hematopoietic stem cells from human bone marrow and cytokine-mobilized peripheral blood. Stem Cells 2000;18:183-9.