Prevalence and etiology of persistently elevated alanine aminotransferase levels in healthy Iranian blood donors

Journal of Gastroenterology and Hepatology (Australia)

Volumn 20, Issue 2, 2005, Pages 229-233

  Pourshams, Akram ^a   Malekzadeh, Reza ^a   Monavvari, Arezoo ^a   Akbari, Mohammad R ^a   Mohamadkhani, Ashraf ^a   Yarahmadi, Shahin ^a   Seddighi, Nahid ^a   Mohamadnejad, Mehdi ^a   Sotoudeh, Masoud ^a   Madjlessi, Amir ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Body mass index; Iran; Metabolic syndrome; Non alcoholic steatohepatitis; Obesity

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ESTROGEN; HEPATITIS B SURFACE ANTIGEN; HEPATITIS C ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL LIVER DISEASE; ARTICLE; BLOOD DONOR; BODY MASS; CONTROLLED STUDY; DRUG INDUCED DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEPATITIS C; HUMAN; IRAN; LIVER DISEASE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; NONALCOHOLIC FATTY LIVER; PREVALENCE; PRIORITY JOURNAL;

EID: 20044368226     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2004.03511.x     Document Type: Article

References (29)

1. Hoyert DL, Arias E, Smith BL, Murphy SL, Kochanek KD. Death and death rate in the United States. National Vital Statistic Reports. 2001; 49: 1-113.
2. Naghavi M. Etiology of death in 18 provinces of Iran in year 2001. In: Ministry of Health and Medical Education IR Iran. 2003.
3. Pratt DS, Kaplan MM. Laboratory tests. In: Schieff ER, Sorrell MF, Maddrey WC, eds. Schiff's Disease of the Liver, Vol. 1, 8th edn. Philadelphia: Lippincott-Raven, 1999; 205-44.
4. Azimi K, Sarafi M, Alavian SM, Alawi M, Mikaeli J, Malekzadeh R. Causes of cirrhosis in cirrhotic patients in Shariati hospital. Govaresh 2002; 37: 19-26 (in Farsi).
5. Kodali VP, Gordon SC, Silverman AL, McCray DG. Cryptogenic liver disease in the United States: further evidence for non-A, non-B, and non-C hepatitis. Am. J. Gatroenterol. 1994; 89: 1836-9.
6. Caldwell SH, Oelsner DH, Iezzoni JC, Hespenheide EE, Battle EH. Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease. Hepatology 1999; 29: 664-9.
7. Bugianesi E, Leone N, Vanni E et al. Expanding the natural history of non-alcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology 2002; 23: 134-40.
8. US Department of Health and Human Services. Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults. Washington, DC: US Department of Health and Human Services, 1998.
9. Mohammadnejad M, Pourshams A, Malekzadeh R et al. Healthy ranges of serum alanine aminotransferase levels in Iranian blood donors. World J. Gastroenterol. 2003; 9: 2322-4.
10. Greenberger NJ. History taking and physical examination for the patients with liver disease. In: Schieff ER, Sorrell MF, Maddrey WC, eds. Schiff's Disease of the Liver, Vol. 1, 9th edn. Philadelphia: Lippincott-Raven, 2003; 3-16.
11. National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002; 106: 3143-421.
12. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabetes Med. 1998; 15: 539-53.
13. Parulekar SG, Bree RL. Liver. In: McGahan JP, Goldberg BB, eds. Diagnostic Ultrasound: a Logical Approach. Philadelphia: Lippincott-Raven, 1998; 599-691.
14. Anderson NA, Raafat A, Shwe KH et al. UK multicentre study on blood donors for surrogate markers of non-A non-B hepatitis. Part I: alanine transferase and anti-HBC testing. Transfus. Med. 1992; 2: 301-10.
15. Ruhl CE, Everhart JE. Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States. Gastroenterology 2003; 124: 71-9.
16. Piton A, Poynard T, Imbert-Bismut F et al. Factors associated with serum alanine transaminase activity in healthy subjects: consequences for the definition of normal values, for selection of blood donors and for patients with chronic hepatitis C. MULTIVIRC Group. Hepatology 1998; 27: 1213-19.
17. Falck-Ytter Y, Younossi ZM, Marchesini G, McCullough AJ. Clinical features and natural history of non-alcoholic steatosis syndromes. Semin. Liver Dis. 2001; 21: 17-26.
18. Merat S, Malekzadeh R, Rezvan H, Khatibian M. Hepatitis B in Iran. Arch. Iranian Med. 2000; 3: 192-201.
19. Rezvan H, Ahmadi I, Farhadi M, Tardyan S. A preliminary study of prevalence of HCV infection in healthy Iranian blood donors. Vox Sang. 1994; 67: 149.
20. Mokri A. Brief overview of the status of drug abuse in Iran. Arch. Iranian Med. 2002; 5: 184-90.
21. Schilsky ML, Tavill AS. Wilson's disease. In: Schieff ER, Sorrell MF, Maddrey WC, eds. Schiff's Disease of the Liver, Vol. 2, 9th edn. Philadelphia: Lippincott-Raven, 2003; 1168-86.
22. Sveger T. Liver disease in α1-antitrypsin deficiency detected by screening of 200,000 infants. N. Engl. J. Med. 1976; 294: 1316-21.
23. Boberg KM, Aadland E, Jahnsen J, Raknerud N, Stiris M, Bell H. Incidence and prevalence of primary biliary cirrhosis, primary sclerosing cholangitis, and autoimmune hepatitis in a Norwegian population. Scand. J. Gastroenterol. 1998; 33: 99-103.
24. Marchesini G, Bugianesi E, Gabriele F et al. Non-alcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology 2003; 37: 917-23. Erratum In: Hepatology 2003; 38: 536.
25. Marchesini G, Bugianesi E, Gabriele F et al. Non-alcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology 2003; 37: 917-23. Erratum In: Hepatology 2003; 38: 536.
26. Willner IR, Waters B, Patil RS, Reuben A, Morelli J, Riely C. Ninety patients with non-alcoholic steatohepatitis: insulin resistance, familial tendency, and severity of disease. Am. J. Gatroenterol. 2001; 96: 2957-61.
27. Azizi F, Salehi P, Etemadi A, Zahedi-Asl S. Prevalence of metabolic syndrome in an urban population: Tehran lipid and glucose study. Diabetes Res. Clin. Pract. 2003; 61: 29-37.
28. Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 2002; 287: 356-9.
29. Sotoudehmanesh R, Ali Asgari A, Sotoudeh M, Abedi Ardakani B, Tavangar SM, Malekzadeh R. Silent liver diseases in an autopsy-based study. Gut 2002; 51 (Suppl. III): A257.