Monosomy 7 associated with pediatric acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS): Successful management by allogeneic hematopoietic stem cell transplant (HSCT)

Bone Marrow Transplantation

Volumn 35, Issue 2, 2005, Pages 143-149

  Troubaugh Lotrario, A D ^a   Kletzel, M ^b   Quinones, R R ^a   McGavran, L ^a   Proytcheva, M A ^b   Hunger, S P ^a,c   Malcolm, J ^a   Schissel, D ^a   Hild, E ^a   Giller, Roger H ^a,d  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d CHILDREN S HOSPITAL   (United States)

Author keywords

Acute myeloid leukemia; Monosomy 7; Myelodysplastic syndrome; Pediatric

Indexed keywords

ASPARAGINASE; BUSULFAN; CYCLOPHOSPHAMIDE; CYTARABINE; ETOPOSIDE; FLUDARABINE; INTERLEUKIN 2;

ACUTE GRANULOCYTIC LEUKEMIA; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ARTICLE; CANCER MORTALITY; CANCER SURVIVAL; CHILD; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; DISEASE ASSOCIATION; DRUG FATALITY; FEMALE; FOLLOW UP; GRAFT VERSUS HOST REACTION; GRAFT VERSUS LEUKEMIA EFFECT; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTION COMPLICATION; LEUKEMIA REMISSION; MALE; MONOSOMY 7; MUCOSA INFLAMMATION; MULTIPLE ORGAN FAILURE; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; SEPSIS; SURVIVAL RATE; TREATMENT OUTCOME;

ACUTE DISEASE; ADOLESCENT; CAUSE OF DEATH; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 7; DISEASE MANAGEMENT; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; LEUKEMIA, MYELOID; MALE; MONOSOMY; MYELODYSPLASTIC SYNDROMES; NEOPLASMS, SECOND PRIMARY; REMISSION INDUCTION; RETROSPECTIVE STUDIES; SURVIVAL RATE; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 19944433683     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1704753     Document Type: Article

References (25)

1. Wheatley K, Burnett A, Goldstone A et al. A simple, robust, validated and highly predictive index for the determination of risk-directed therapy in acute myeloid leukaemia derived from the MRC AML 10 trial. Br J Haematol 1999; 107: 69-79.
2. Baranger L, Baruchel A, Leverger G et al. Monosomy-7 in childhood hemopoietic disorders. Leukemia 1990; 4: 345-349.
3. Passmore SJ, Hann IM, Stiller CA et al. Pediatric myelodysplasia: a study of 68 children and a new prognostic scoring system. Blood 1995; 85: 1742-1750.
4. Hasle H, Aric M, Basso G et al. Myelodysplastic syndrome, juvenile myelomonocytic leukemia, and acute myeloid leukemia associated with complete or partial monosomy 7. Leukemia 1999; 13: 376-385.
5. Leverger G, Bernheim A, Daniel M et al. Cytogenetic study of 130 childhood acute nonlymphocytic leukemias. Med Pediatr Oncol 1988; 16: 227-232.
6. Hasle H. Myelodysplastic syndromes in childhood. Classification, epidemiology, and treatment. Leuk Lymphoma. 1994; 13: 11-26.
7. Woods WG, Kobrinsky N, Buckley JD et al. Timed-sequential induction therapy improves postremission outcome in acute myeloid leukemia: a report from the Children's Cancer Group. Blood 1996; 87: 4979-4989.
8. Capizzi RL, Poole M, Cooper MR et al. Treatment of poor risk acute leukemia with sequential high-dose AraC and asparaginase. Blood 1984; 63: 694-700.
9. Kaplan E, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958; 53: 457.
10. Lansky SB, List MA, Lansky LL et al. The measurement of performance in childhood cancer patients. Cancer 1987; 60: 1651-1656.
11. Hunger SP, Sun T, Boswell AF et al. Hyperdiploidy and E2A-PBX1 fusion in an adult with t(1;19)+ acute lymphoblastic leukemia: case report and review of the literature. Genes Chromosomes Cancer 1997; 20: 392-398.
12. Mitelman F. ISCN (1995). An International System for Human Cytogenetic Nomenclature. S Karger: Basel, 1995.
13. Soiffer RJ, Murray C, Gonin R, Ritz J. Effect of low-dose interleukin-2 on disease relapse after T-cell-depleted allogeneic bone marrow transplantation. Blood 1994; 84: 964-971.
14. Woods WG, Neudorf S, Gold S et al. A comparison of allogeneic bone marrow transplantation, autologous bone marrow transplantation, and aggressive chemotherapy in children with acute myeloid leukemia in remission: a report from the Children's Cancer Group. Blood 2001; 97: 56-62.
15. Chang M, Raimondi SC, Ravindranath Y et al. Prognostic factors in children and adolescents with acute myeloid leukemia (excluding children with Down syndrome and acute promyelocytic leukemia): univariate and recursive partitioning analysis of patients treated on Pediatric Oncology Group (POG) Study 8821. Leukemia 2000; 14: 1201-1207.
16. Guinan EC, Tarbell NJ, Tantravahi R, Weinstein HJ. Bone marrow transplantation for children with myelodysplastic syndromes. Blood 1989; 73: 619-622.
17. Groupe Français de Cytogénétique Hé matologique. Forty-four cases of childhood myelodysplasia with cytogenetics, documented by the Groupe Français de Cytogé nétique Hématologique. Leukemia 1997; 11: 1478-1485.
18. Kardos G, Baumann I, Passmore S et al. Refractory anemia in childhood: a retrospective analysis of 67 patients with particular reference to monosomy 7. Blood 2003; 102: 1997-2003.
19. Webb D, Passmore S, Hann I et al. Results of treatment of children with refractory anemia with excess blasts (RAEB) and RAEB in transformation (RAEBt) in Great Britain 1990-99. Br J Haematol 2002; 117: 33-39.
20. Woods W, Barnard D, Alonzo T et al. Prospective study of 90 children requiring treatment for juvenile myelomonocytic leukemia or myelodysplastic syndrome: A report from the Children's Cancer Group. J Clin Oncol 2002; 20: 434-440.
21. Grimwade D, Walker H, Oliver F et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. Blood 1998; 92: 2322-2333.
22. Luna-Fineman S, Shannon KM, Atwater SK et al. Myelodysplastic and myeloproliferative disorders of childhood: a study of 167 patients. Blood 1999; 93: 459-466.
23. Sasaki H, Manabe A, Kojima S et al. Myelodysplastic syndrome in childhood: a retrospective study of 189 patients in Japan. Leukemia 2001; 15: 1713-1720.
24. Vardiman J, Harris N, Brunning R. The World Health Organization classification of the myeloid neoplasms. Blood 2002; 100: 2292-2302.
25. Hasle H, Niemeyer CM, Chessels HM et al. A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases. Leukemia 2003; 17: 277-282.