Dementia associated with the antiphospholipid syndrome: Clinical and radiological characteristics of 30 patients

Rheumatology

Volumn 44, Issue 1, 2005, Pages 95-99

  Gomez Puerta J A ^a   Cervera, R ^a   Calvo, L M ^a   Gomez Anson B ^a   Espinosa, G ^a   Claver, G ^a   Bucciarelli, S ^a   Bove A ^a   Ramos Casals, M ^a   Ingelmo, M ^a   Font, J ^a  

^a HOSPITAL CLÍNIC   (Spain)

Author keywords

Antiphospholipid syndrome; Binswanger's disease; Dementia; Multi infarct dementia; Sneddon's syndrome; Vascular dementia

Indexed keywords

ACETYLSALICYLIC ACID; CARDIOLIPIN ANTIBODY; DIPYRIDAMOLE; LUPUS ANTICOAGULANT; STEROID;

ADOLESCENT; ADULT; AGED; ANTICOAGULANT THERAPY; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; BASAL GANGLION; BINSWANGER ENCEPHALOPATHY; BRAIN ATROPHY; BRAIN INFARCTION; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; CLINICAL FEATURE; COMPUTER ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DEEP VEIN THROMBOSIS; DEMENTIA; DISABILITY; ECHOCARDIOGRAPHY; FEMALE; HUMAN; LUPUS ERYTHEMATOSUS; MALE; MEDICAL LITERATURE; MEDLINE; MIGRAINE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PUBLICATION; RADIODIAGNOSIS; SEIZURE; SNEDDON SYNDROME; SPONTANEOUS ABORTION; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOCYTOPENIA; VALVULAR HEART DISEASE;

ADOLESCENT; ADULT; AGED; ANTIPHOSPHOLIPID SYNDROME; DEMENTIA; FEMALE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; TOMOGRAPHY, X-RAY COMPUTED;

EID: 19944429448     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/keh408     Document Type: Article

References (36)

1. Roman GC. Vascular dementia: distinguishing characteristics, treatment, and prevention. J Am Geriatr Soc 2003;51:S296-S304.
2. Cervera R, Piette JC, Font J et al. Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients. Arthritis Rheum 2002;46: 1019-27.
3. Chapman J, Rand JH, Brey RL et al. Non-stroke neurological syndromes associated with antiphospholipid antibodies: evaluation of clinical and experimental studies. Lupus 2003;12:514-17.
4. Chapman J, Abu-Katash M, Inzelberg R et al. Prevalence and clinical features of dementia associated with the antiphospholipid syndrome and circulating anticoagulants. J Neurol Sci 2002;203-204:81-4.
5. Erkan D, Yazici Y, Sobel R, Lockshin MD. Primary antiphospholipid syndrome: functional outcome after 10 years. J Rheumatol 2000;27: 2817-21.
6. Mosek A, Yust I, Treves TA, Vardinon N, Korczyn AD, Chapman J. Dementia and antiphospholipid antibodies. Dement Geriatr Cogn Disord 2000;11:33-8.
7. Sastre-Garriga J, Montalban X. APS and the brain. Lupus 2003; 12:877-82.
8. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV), Washington, 1994.
9. Tan EM, Cohen AS, Fries JF et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7.
10. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997;40:1725.
11. Wilson WA, Gharavi AE, Koike T et al. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop. Arthritis Rheum 1999;42:1309-11.
12. Asherson RA, Mercey D, Philips G et al. Recurrent stroke and multi-infarct dementia in systemic lupus erythematosus: association with antiphospholipid antibodies. Ann Rheum Dis 1987;46:605-11.
13. Coull B, Bourdette DN, Goodnight SH Jr, Briley DP, Hart R. Multiple cerebral infarctions and dementia associated with anti-cardiolipin antibodies. Stroke 1987;18:1107-12.
14. Montalbán J, Fernández J, Arderiu A et al. Demencia multiinfártica asociada a anticuerpos antifosfolí pido. Presentación de dos casos. Med Clin (Barc) 1989;93:424-6.
15. Asherson RA, Khamashta MA, Gil A et al. Cerebrovascular disease and antiphospholipid antibodies in systemic lupus erythematosus, lupus-like disease, and the primary antiphospholipid syndrome. Am J Med 1989;86:391-9.
16. Westerman EM, Miles JM, Backnova M, Sundst W. Neuropathologic findings in multi-infarct dementia associated with anticardiolipin antibody. Arthritis Rheum 1992;35:1038-41.
17. Charles PD, Fenichel GM. Sneddon and antiphospholipid antibody syndromes causing bilateral thalamic infarction. Pediatr Neurol 1994;10:262-3.
18. Kurita A, Hasunuma T, Mochio S, Shimada T, Isogai Y, Kurahashi T. A young case with multi-infarct dementia associated with lupus anticoagulant. Intern Med 1994;33:373-5.
19. Robin C, Gonnaud PM, Durieu I et al. Progressive lupus dementia. 2 cases with or without antiphospholipid antibodies. Rev Neurol (Paris) 1995;151:699-707.
20. Serra-Mestres J. Antiphospholipid antibodies and Binswanger's disease. Neurology 1996;46:291-2.
21. van Horn G, Arnett FC, Dimachkie MM. Reversible dementia and chorea in a young woman with the lupus anticoagulant. Neurology 1996;46:1599-603.
22. Tomimoto H, Akiguchi I, Ohtani R, Yagi H, Ogura S, Wakita H. Effects of an antithrombin drug in patients with subacute exacerbations of Binswanger disease. Intern Med 2000;39:966-9.
23. Rich MW. Sneddon syndrome and dementia. Mayo Clin Proc, 1999;74:1306.
24. Fukui T, Kawamura M, Hasegawa Y, Kato T, Kaga E. Multiple cognitive impairments associated with systemic lupus erythematosus and antiphospholipid antibody syndrome: a form of progressive vascular dementia? Eur Neurol 2000;43:115-16.
25. Hilker R, Thiel A, Geisen C, Rudolf J. Cerebral blood flow and glucose metabolism in multi-infarct-dementia related to primary antiphospholipid antibody syndrome. Lupus 2000;9:311-16.
26. Rodríguez Campello A, Roquer J, Munteis F, Gomis M, Pou A. Sneddon syndrome presenting with dementia. Neurología 2002;17: 394-5.
27. Juby A, David JA, Genge T, McElhaney J. Anticardiolipin antibodies in two elderly subpopulations. Lupus 1995;4:482-5.
28. Soltész P, Veres K, Lakos G, Kiss E, Muszbek L, Szegedi G. Evaluation of clinical and laboratory features of antiphospholipid syndrome: a retrospective study of 637 patients. Lupus 2003;12: 302-7.
29. Shrot S, Katzav A, Korczyn AD et al. Behavioral and cognitive deficits occur only after prolonged exposure of mice to antiphospholipid antibodies. Lupus 2002;11:736-43.
30. Francès C, Papo T, Wechsler B, Laporte JL, Biousse V, Piette JC. Sneddon syndrome with or without antiphospholipid antibodies. A comparative study in 46 patients. Medicine 1999;78:209-19.
31. Khamashta MA, Cervera R, Asherson RA et al. Association of antibodies against phospholipids with heart valve disease in systemic lupus erythematosus. Lancet 1990;335:1541-4.
32. Cervera R. Recent advances in antiphospholipid antibody-related valvulopathies. J Autoimmun 2000;15:123-5.
33. Shoenfeld Y, Lev S, Blatt I et al. Features associated with epilepsy in the antiphospholipid syndrome. J Rheumatol 2004;31:1344-8.
34. Csépány T, Bereczki D, Kollar J, Sikula J, Kiss E, Csiba L. MRI findings in central nervous system systemic lupus erythematosus are associated with immunoserological parameters and hypertension. J Neurol 2003;250:1348-54.
35. Kao CH, Lan JL, Hsieh JF et al. Evaluation of regional cerebral blood flow with 99mTc-HMPAO in primary antiphospholipid antibody syndrome. J Nucl Med 1999;40:1446-50.
36. Vermeer SE, Prins ND, den Heijer T, Holman A, Koudstaal PJ, Breteler MM. Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med 2003;348:1215-22.