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Volumn 5, Issue 2-3, 2005, Pages 241-250

Pancreatic proteases in serum induce leukocyte-endothelial adhesion and pancreatic microcirculatory failure

Author keywords

Acute pancreatitis; Adhesion molecules; In vivo confocal microscopy; Microcirculation; Protease inhibition

Indexed keywords

CD11B ANTIGEN; CELL ADHESION MOLECULE; ELASTASE; GABEXATE MESILATE; INTERCELLULAR ADHESION MOLECULE 1; NAFAMSTAT MESILATE; PANCREAS ENZYME; PROTEINASE; PROTEINASE INHIBITOR; TRYPSIN;

EID: 19944424483     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1159/000085278     Document Type: Article
Times cited : (42)

References (72)
  • 2
    • 0025265375 scopus 로고
    • Does stress play a role in the development of severe pancreatitis in rats?
    • Yamaguchi H, Kimura T, Nawata H: Does stress play a role in the development of severe pancreatitis in rats? Gastroenterology 1990;98:1682-1688.
    • (1990) Gastroenterology , vol.98 , pp. 1682-1688
    • Yamaguchi, H.1    Kimura, T.2    Nawata, H.3
  • 3
    • 0028004269 scopus 로고
    • Hemorrhagic hypotension induces arteriolar vasomotion and intermittent capillary perfusion in rat pancreas
    • Vollmar B, Preissler G, Menger MD: Hemorrhagic hypotension induces arteriolar vasomotion and intermittent capillary perfusion in rat pancreas. Am J Physiol 1994;267:H1936-H1940.
    • (1994) Am J Physiol , vol.267
    • Vollmar, B.1    Preissler, G.2    Menger, M.D.3
  • 4
    • 0029871962 scopus 로고    scopus 로고
    • Small-volume resuscitation restores hemorrhage-induced microcirculatory disorders in rat pancreas
    • Vollmar MD, Preissler G, Menger MD: Small-volume resuscitation restores hemorrhage-induced microcirculatory disorders in rat pancreas. Crit Care Med 1996;24:445-450.
    • (1996) Crit Care Med , vol.24 , pp. 445-450
    • Vollmar, M.D.1    Preissler, G.2    Menger, M.D.3
  • 5
    • 0027398161 scopus 로고
    • Improvement of impaired pancreatic microcirculation by isovolemic hemodilution protects pancreatic morphology in acute biliary pancreatitis
    • Klar E, Mall G, Messmer K, Herfarth C, Rattner DW, Warshaw AL: Improvement of impaired pancreatic microcirculation by isovolemic hemodilution protects pancreatic morphology in acute biliary pancreatitis. Surg Gynecol Obstet 1993;176:144-150.
    • (1993) Surg Gynecol Obstet , vol.176 , pp. 144-150
    • Klar, E.1    Mall, G.2    Messmer, K.3    Herfarth, C.4    Rattner, D.W.5    Warshaw, A.L.6
  • 6
    • 0027376073 scopus 로고
    • Hyperoncotic ultra-high molecular weight dextran solutions reduce trypsinogen activation, prevent acinar necrosis, and lower mortality in rodent pancreatitis
    • Schmidt J, Fernandez-del-Castillo C, Rattner DW, Lewandrowski KB, Messmer K, Warshaw AL: Hyperoncotic ultra-high molecular weight dextran solutions reduce trypsinogen activation, prevent acinar necrosis, and lower mortality in rodent pancreatitis. Am J Surg 1993;165:40-44.
    • (1993) Am J Surg , vol.165 , pp. 40-44
    • Schmidt, J.1    Fernandez-del-Castillo, C.2    Rattner, D.W.3    Lewandrowski, K.B.4    Messmer, K.5    Warshaw, A.L.6
  • 8
    • 0028585877 scopus 로고
    • Impact of microcirculatory flow pattern changes on the development of acute edematous and necrotizing pancreatitis in rabbit pancreas
    • Klar E, Schratt W, Foitzik T, Buhr H, Herfarth C, Messmer K: Impact of microcirculatory flow pattern changes on the development of acute edematous and necrotizing pancreatitis in rabbit pancreas. Dig Dis Sci 1994;39:2639-2644.
    • (1994) Dig Dis Sci , vol.39 , pp. 2639-2644
    • Klar, E.1    Schratt, W.2    Foitzik, T.3    Buhr, H.4    Herfarth, C.5    Messmer, K.6
  • 9
    • 0025258919 scopus 로고
    • Pancreatic ischemia in experimental acute pancreatitis: Mechanisms, significance and therapy
    • Klar E, Messmer K, Warshaw AL, Herfarth C: Pancreatic ischemia in experimental acute pancreatitis: Mechanisms, significance and therapy. Br J Surg 1990;77:1205-1210.
    • (1990) Br J Surg , vol.77 , pp. 1205-1210
    • Klar, E.1    Messmer, K.2    Warshaw, A.L.3    Herfarth, C.4
  • 10
    • 0029789675 scopus 로고    scopus 로고
    • In vivo documentation of an arteriovenous shunt in rat pancreatic acinar tissue
    • Menger MD, Vollmar B: In vivo documentation of an arteriovenous shunt in rat pancreatic acinar tissue. Pancreas 1996;13:125-129.
    • (1996) Pancreas , vol.13 , pp. 125-129
    • Menger, M.D.1    Vollmar, B.2
  • 11
    • 0031891135 scopus 로고    scopus 로고
    • Technetium-99m-labeled white blood cells: A new method to define the local and systemic role of leukocytes in acute experimental pancreatitis
    • Werner J, Dragotakes SC, Fernandez-del Castillo C: Technetium-99m-labeled white blood cells: A new method to define the local and systemic role of leukocytes in acute experimental pancreatitis. Ann Surg 1998;227:86-94.
    • (1998) Ann Surg , vol.227 , pp. 86-94
    • Werner, J.1    Dragotakes, S.C.2    Fernandez-del Castillo, C.3
  • 12
    • 0029875763 scopus 로고    scopus 로고
    • Ischemia-reperfusion-induced pancreatic microvascular injury: An intravital fluorescence microscopic study in rats
    • Menger MD, Bonkhoff H, Vollmar B: Ischemia-reperfusion-induced pancreatic microvascular injury: An intravital fluorescence microscopic study in rats. Dig Dis Sci 1996;41:823-830.
    • (1996) Dig Dis Sci , vol.41 , pp. 823-830
    • Menger, M.D.1    Bonkhoff, H.2    Vollmar, B.3
  • 14
    • 0028126005 scopus 로고
    • Altered expression of adhesion molecules (L-selectin and Mac-1) on granulocytes during storage
    • Wikman A, Lundahl J, Fernvik E, Shanwell A: Altered expression of adhesion molecules (L-selectin and Mac-1) on granulocytes during storage. Transfusion 1994;34:167-171.
    • (1994) Transfusion , vol.34 , pp. 167-171
    • Wikman, A.1    Lundahl, J.2    Fernvik, E.3    Shanwell, A.4
  • 15
    • 0028928480 scopus 로고
    • Effects of cell purification methods on CD11b and L-selectin expression as well as the adherence and activation of leucocytes
    • Macey MG, McCarthy DA, Vordermeier S, Newland AC, Brown KA: Effects of cell purification methods on CD11b and L-selectin expression as well as the adherence and activation of leucocytes. J Immunol Methods 1995;181:211-219.
    • (1995) J Immunol Methods , vol.181 , pp. 211-219
    • Macey, M.G.1    McCarthy, D.A.2    Vordermeier, S.3    Newland, A.C.4    Brown, K.A.5
  • 19
    • 0032870590 scopus 로고    scopus 로고
    • In vivo confocal scanning laser microscopy of human skin II: Advantages in instrumentation in comparison with histology
    • Rajadhyaksha M, González S, Zavislan JM, Anderson RR, Webb RH: In vivo confocal scanning laser microscopy of human skin II: Advantages in instrumentation in comparison with histology. J Invest Dermatol 1999;113:293-303.
    • (1999) J Invest Dermatol , vol.113 , pp. 293-303
    • Rajadhyaksha, M.1    González, S.2    Zavislan, J.M.3    Anderson, R.R.4    Webb, R.H.5
  • 20
    • 0017620937 scopus 로고
    • The application of stereological principles to morphometry of the microcirculation in different tissues
    • Schmid-Schoenbein GW, Zweifach BW, Kovalcheck S: The application of stereological principles to morphometry of the microcirculation in different tissues. Microvasc Res 1977;14:303-317.
    • (1977) Microvasc Res , vol.14 , pp. 303-317
    • Schmid-Schoenbein, G.W.1    Zweifach, B.W.2    Kovalcheck, S.3
  • 22
    • 0029003099 scopus 로고
    • Ischemia reperfusion of the pancreas: A new in vivo model for acute pancreatitis in rats
    • Hoffmann TF, Leiderer R, Waldner H, Arbogast S, Messmer K: Ischemia reperfusion of the pancreas: A new in vivo model for acute pancreatitis in rats. Res Exp Med 1995;195:125-144.
    • (1995) Res Exp Med , vol.195 , pp. 125-144
    • Hoffmann, T.F.1    Leiderer, R.2    Waldner, H.3    Arbogast, S.4    Messmer, K.5
  • 24
    • 0024367923 scopus 로고
    • Leukocyte adherence to venular endothelium during ischemia-reperfusion
    • Granger DN, Benoit JN, Suzuki M, Grisham MB: Leukocyte adherence to venular endothelium during ischemia-reperfusion. Am J Physiol 1989;257:G683-G688.
    • (1989) Am J Physiol , vol.257
    • Granger, D.N.1    Benoit, J.N.2    Suzuki, M.3    Grisham, M.B.4
  • 25
    • 0023387994 scopus 로고
    • Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface
    • Miller LJ, Bainton DF, Borregaard N, Springer TA: Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface. J Clin Invest 1987;80:535-544.
    • (1987) J Clin Invest , vol.80 , pp. 535-544
    • Miller, L.J.1    Bainton, D.F.2    Borregaard, N.3    Springer, T.A.4
  • 27
    • 0031771392 scopus 로고    scopus 로고
    • The effects of neutrophil depletion on a completely noninvasive model of acute pancreatitis-associated lung injury
    • Bhatia M, Saluja A, Hofbauer B, Lee HS, Frossard J-L, Steer ML: The effects of neutrophil depletion on a completely noninvasive model of acute pancreatitis-associated lung injury. Int J Pancreatol 1998;24:77-83.
    • (1998) Int J Pancreatol , vol.24 , pp. 77-83
    • Bhatia, M.1    Saluja, A.2    Hofbauer, B.3    Lee, H.S.4    Frossard, J.-L.5    Steer, M.L.6
  • 28
    • 0028797055 scopus 로고
    • Anti-neutrophil antibody attenuates the severity of acute lung injury in rats with experimental acute pancreatitis
    • Inoue S, Nakao A, Kishimoto W: Anti-neutrophil antibody attenuates the severity of acute lung injury in rats with experimental acute pancreatitis. Arch Surg 1995;130:93-98.
    • (1995) Arch Surg , vol.130 , pp. 93-98
    • Inoue, S.1    Nakao, A.2    Kishimoto, W.3
  • 29
    • 0025034637 scopus 로고
    • Granulocyte elastase in assessment of severity of acute pancreatitis: Comparison with acute-phase proteins C-reactive protein, alpha 1-antitrypsin, and protease inhibitor alpha 2-macroglobulin
    • Gross V, Scholmerich J, Leser HG, Salm R, Lausen M, Ruckauer K, Schoffel U, Lay L, Heinisch A, Farthmann EH: Granulocyte elastase in assessment of severity of acute pancreatitis: Comparison with acute-phase proteins C-reactive protein, alpha 1-antitrypsin, and protease inhibitor alpha 2-macroglobulin. Dig Dis Sci 1990;35:97-105.
    • (1990) Dig Dis Sci , vol.35 , pp. 97-105
    • Gross, V.1    Scholmerich, J.2    Leser, H.G.3    Salm, R.4    Lausen, M.5    Ruckauer, K.6    Schoffel, U.7    Lay, L.8    Heinisch, A.9    Farthmann, E.H.10
  • 30
    • 0025939982 scopus 로고
    • Clinical usefulness of polymorphonuclear elastase in predicting the severity of acute pancreatitis: Results of a multicentre study
    • Dominguez-Munoz JE, Carballo F, Garcia MJ, de Diego JM, Rabago L, Simon MA, de la Morena J: Clinical usefulness of polymorphonuclear elastase in predicting the severity of acute pancreatitis: results of a multicentre study. Br J Surg 1991;78:1230-1234.
    • (1991) Br J Surg , vol.78 , pp. 1230-1234
    • Dominguez-Munoz, J.E.1    Carballo, F.2    Garcia, M.J.3    De Diego, J.M.4    Rabago, L.5    Simon, M.A.6    De La Morena, J.7
  • 31
    • 0025907543 scopus 로고
    • PMN-elastase in comparison with CRP, antiproteases, and LDH as indicators of necrosis in human acute pancreatitis
    • Uhl W, Buchler M, Malfertheiner P, Martini M, Beger HG: PMN-elastase in comparison with CRP, antiproteases, and LDH as indicators of necrosis in human acute pancreatitis. Pancreas 1991;6:253-259.
    • (1991) Pancreas , vol.6 , pp. 253-259
    • Uhl, W.1    Buchler, M.2    Malfertheiner, P.3    Martini, M.4    Beger, H.G.5
  • 32
    • 0031978507 scopus 로고    scopus 로고
    • Leukocyte-endothelial cell interactions: Molecular mechanisms and implications in gastrointestinal disease
    • Panés J, Granger DN: Leukocyte-endothelial cell interactions: molecular mechanisms and implications in gastrointestinal disease. Gastroenterology 1998;114:1066-1090.
    • (1998) Gastroenterology , vol.114 , pp. 1066-1090
    • Panés, J.1    Granger, D.N.2
  • 33
  • 34
    • 0033044628 scopus 로고    scopus 로고
    • The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury
    • Frossard J-L, Saluja A, Bhagat L, Lee HS, Bhatia M, Hofbauer B, Steer ML: The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury. Gastroenterology 1999;116:694-701.
    • (1999) Gastroenterology , vol.116 , pp. 694-701
    • Frossard, J.-L.1    Saluja, A.2    Bhagat, L.3    Lee, H.S.4    Bhatia, M.5    Hofbauer, B.6    Steer, M.L.7
  • 36
    • 0032985372 scopus 로고    scopus 로고
    • A novel diaminopyridine derivative prevents excessive leukocyte infiltration in aggravation of acute necrotizing pancreatitis
    • Yamauchi J, Sunamura M, Shibuya K, Takeda K, Kobari M, Matsuno S: A novel diaminopyridine derivative prevents excessive leukocyte infiltration in aggravation of acute necrotizing pancreatitis. Digestion 1999;60(suppl 1):40-46.
    • (1999) Digestion , vol.60 , Issue.1 SUPPL. , pp. 40-46
    • Yamauchi, J.1    Sunamura, M.2    Shibuya, K.3    Takeda, K.4    Kobari, M.5    Matsuno, S.6
  • 37
    • 0030028840 scopus 로고    scopus 로고
    • LFA-1 (CD11a/CD18) and ICAM-1 (CD-54) antibodies attenuate superoxide anion release from polymorphonuclear leukocytes in rats with experimental acute pancreatitis
    • Inoue S, Nakao A, Kishimoto W, Murakami H, Harada A, Nonami T, Takagi H: LFA-1 (CD11a/CD18) and ICAM-1 (CD-54) antibodies attenuate superoxide anion release from polymorphonuclear leukocytes in rats with experimental acute pancreatitis. Pancreas 1996;12:183-188.
    • (1996) Pancreas , vol.12 , pp. 183-188
    • Inoue, S.1    Nakao, A.2    Kishimoto, W.3    Murakami, H.4    Harada, A.5    Nonami, T.6    Takagi, H.7
  • 38
    • 0024420563 scopus 로고
    • Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors
    • Kishimoto TK, Jutila MA, Berg EL, Butcher EC: Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors. Science 1989;245:1238-1241.
    • (1989) Science , vol.245 , pp. 1238-1241
    • Kishimoto, T.K.1    Jutila, M.A.2    Berg, E.L.3    Butcher, E.C.4
  • 39
    • 0032906182 scopus 로고    scopus 로고
    • Platelet-activating factor antagonist (TCV-309) attenuates the priming effects of bronchoalveolar macrophages in cerulein-induced pancreatitis rats
    • Yamaguchi Y, Matsumura F, Liang J, Okabe K, Matsuda T, Ohshiro H, Ishihara K, Akizuki E, Yamada S, Ogawa M: Platelet-activating factor antagonist (TCV-309) attenuates the priming effects of bronchoalveolar macrophages in cerulein-induced pancreatitis rats. Pancreas 1999;18:355-363.
    • (1999) Pancreas , vol.18 , pp. 355-363
    • Yamaguchi, Y.1    Matsumura, F.2    Liang, J.3    Okabe, K.4    Matsuda, T.5    Ohshiro, H.6    Ishihara, K.7    Akizuki, E.8    Yamada, S.9    Ogawa, M.10
  • 40
    • 0036090346 scopus 로고    scopus 로고
    • Control of leukocyte rolling velocity in TNF-alpha-induced inflammation by LFA-1 and Mac-1
    • Dunne JL, Ballantyne CM, Beaudet AL, Ley K: Control of leukocyte rolling velocity in TNF-alpha-induced inflammation by LFA-1 and Mac-1. Blood 2002;99:336-341.
    • (2002) Blood , vol.99 , pp. 336-341
    • Dunne, J.L.1    Ballantyne, C.M.2    Beaudet, A.L.3    Ley, K.4
  • 42
    • 0035196691 scopus 로고    scopus 로고
    • Effects of CXC chemokines on neutrophil activation and sequestration in hepatic vasculature
    • Bajt ML, Farhood A, Jaeschke H: Effects of CXC chemokines on neutrophil activation and sequestration in hepatic vasculature. Am J Physiol 2001;281:G1188-G1195.
    • (2001) Am J Physiol , vol.281
    • Bajt, M.L.1    Farhood, A.2    Jaeschke, H.3
  • 43
    • 15444354781 scopus 로고    scopus 로고
    • A monoclonal anti-interleukin 8 antibody (WS-4) inhibits cytokine response and acute lung injury in experimental severe acute necrotizing pancreatitis in rabbits
    • Osman MO, Kristensen JU, Jacobsen NO, Lausten SB, Deleuran B, Deleuran M, Gesser B, Matsushima K, Larsen CG, Jensen SL: A monoclonal anti-interleukin 8 antibody (WS-4) inhibits cytokine response and acute lung injury in experimental severe acute necrotizing pancreatitis in rabbits. Gut 1998;43:232-239.
    • (1998) Gut , vol.43 , pp. 232-239
    • Osman, M.O.1    Kristensen, J.U.2    Jacobsen, N.O.3    Lausten, S.B.4    Deleuran, B.5    Deleuran, M.6    Gesser, B.7    Matsushima, K.8    Larsen, C.G.9    Jensen, S.L.10
  • 44
    • 0030716873 scopus 로고    scopus 로고
    • Early complement system activation and neutrophil priming in acute pancreatitis: Participation of trypsin
    • Acioli JM, Isobe M, Kawasaki S: Early complement system activation and neutrophil priming in acute pancreatitis: participation of trypsin. Surgery 1997;122:909-917.
    • (1997) Surgery , vol.122 , pp. 909-917
    • Acioli, J.M.1    Isobe, M.2    Kawasaki, S.3
  • 45
    • 0034997369 scopus 로고    scopus 로고
    • Evidence for the involvement of phosphatidylinositol 3-kinase in fMLP-stimulated neutrophil adhesion to ICAM-1-transfected cells
    • Pellegatta F, Radaelli A, Heltai S, Yan L, Chierchia SL, Folli F: Evidence for the involvement of phosphatidylinositol 3-kinase in fMLP-stimulated neutrophil adhesion to ICAM-1-transfected cells. J Cardiovasc Pharmacol 2001;37:751-761.
    • (2001) J Cardiovasc Pharmacol , vol.37 , pp. 751-761
    • Pellegatta, F.1    Radaelli, A.2    Heltai, S.3    Yan, L.4    Chierchia, S.L.5    Folli, F.6
  • 46
    • 0036569440 scopus 로고    scopus 로고
    • Signaling pathways involved in IL-8-dependent activation of adhesion through Mac-1
    • Takami M, Terry V, Petruzzelli L: Signaling pathways involved in IL-8-dependent activation of adhesion through Mac-1. J Immunol 2002;168:4559-4566.
    • (2002) J Immunol , vol.168 , pp. 4559-4566
    • Takami, M.1    Terry, V.2    Petruzzelli, L.3
  • 47
    • 0035119023 scopus 로고    scopus 로고
    • Expression of the adhesion molecules Mac-1 and L-selectin on neutrophils in acute pancreatitis is protease- And complement-dependent
    • Hartwig W, Jimenez RE, Fernandez-del-Castillo C, Kelliher A, Jones R, Warshaw AL: Expression of the adhesion molecules Mac-1 and L-selectin on neutrophils in acute pancreatitis is protease- and complement-dependent. Ann Surg 2001;233:371-378.
    • (2001) Ann Surg , vol.233 , pp. 371-378
    • Hartwig, W.1    Jimenez, R.E.2    Fernandez-del-Castillo, C.3    Kelliher, A.4    Jones, R.5    Warshaw, A.L.6
  • 50
    • 0028146346 scopus 로고
    • Interstitial protease activation is the central event in progression to necrotizing pancreatitis
    • Fernandez-del-Castillo C, Schmidt J, Warshaw AL, Rattner DW: Interstitial protease activation is the central event in progression to necrotizing pancreatitis. Surgery 1994;116:497-504.
    • (1994) Surgery , vol.116 , pp. 497-504
    • Fernandez-del-Castillo, C.1    Schmidt, J.2    Warshaw, A.L.3    Rattner, D.W.4
  • 51
    • 0034657240 scopus 로고    scopus 로고
    • Elastase mimics pancreatitis-induced hepatic injury via inflammatory mediators
    • Jaffray C, Yang J, Norman JG: Elastase mimics pancreatitis-induced hepatic injury via inflammatory mediators. J Surg Res 2000;90:95-101.
    • (2000) J Surg Res , vol.90 , pp. 95-101
    • Jaffray, C.1    Yang, J.2    Norman, J.G.3
  • 52
    • 0033866838 scopus 로고    scopus 로고
    • Pancreatic elastase activates pulmonary NF-kB and IkB mimicking pancreatitis-associated ARDS
    • Murphy C, Yang J, Carter G, Mendez C, Norman JG: Pancreatic elastase activates pulmonary NF-kB and IkB mimicking pancreatitis-associated ARDS. Surgery 2000;128:225-231.
    • (2000) Surgery , vol.128 , pp. 225-231
    • Murphy, C.1    Yang, J.2    Carter, G.3    Mendez, C.4    Norman, J.G.5
  • 53
    • 0023268074 scopus 로고
    • Serum elastase 1 in inflammatory pancreatic and gastrointestinal diseases and in renal insufficiency: A comparison with other serum pancreatic enzymes
    • Malfertheiner P, Buchler M, Stanescu A, Uhl W, Ditschuneit H: Serum elastase 1 in inflammatory pancreatic and gastrointestinal diseases and in renal insufficiency: A comparison with other serum pancreatic enzymes. Int J Pancreatol 1987;2:159-170.
    • (1987) Int J Pancreatol , vol.2 , pp. 159-170
    • Malfertheiner, P.1    Buchler, M.2    Stanescu, A.3    Uhl, W.4    Ditschuneit, H.5
  • 54
    • 0025060126 scopus 로고
    • Trypsinogen activation peptides assay in the early prediction of severity of acute pancreatitis
    • Gudgeon AM, Heath D, Hurley PR: Trypsinogen activation peptides assay in the early prediction of severity of acute pancreatitis. Lancet 1990;335:4-8.
    • (1990) Lancet , vol.335 , pp. 4-8
    • Gudgeon, A.M.1    Heath, D.2    Hurley, P.R.3
  • 55
    • 0032943598 scopus 로고    scopus 로고
    • Trypsinogen activation peptides (TAP) in peritoneal fluid as predictors of late histopathologic injury in necrotizing pancreatitis in the rat
    • Schmidt J, Ryschich E, Sinn P, Herfarth C, Klar E: Trypsinogen activation peptides (TAP) in peritoneal fluid as predictors of late histopathologic injury in necrotizing pancreatitis in the rat. Dig Dis Sci 1999;44:823-829.
    • (1999) Dig Dis Sci , vol.44 , pp. 823-829
    • Schmidt, J.1    Ryschich, E.2    Sinn, P.3    Herfarth, C.4    Klar, E.5
  • 57
    • 0036142331 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 promotes neutrophil migration and alveolar capillary leakage in pancreatitis-associated lung injury in the rat
    • Keck T, Balcom JHI, Fernandez-del-Castillo C, Antoniu BA, Warshaw AL: Matrix metalloproteinase-9 promotes neutrophil migration and alveolar capillary leakage in pancreatitis-associated lung injury in the rat. Gastroenterology 2002;122:188-201.
    • (2002) Gastroenterology , vol.122 , pp. 188-201
    • Keck, T.1    Balcom, J.H.I.2    Fernandez-del-Castillo, C.3    Antoniu, B.A.4    Warshaw, A.L.5
  • 59
    • 0017756348 scopus 로고
    • Kinetic studies on the fragmentation of the third component of complement (C3) by trypsin
    • Minta JO, Man D, Movat HZ: Kinetic studies on the fragmentation of the third component of complement (C3) by trypsin. J Immunol 1977;118:2192-2198.
    • (1977) J Immunol , vol.118 , pp. 2192-2198
    • Minta, J.O.1    Man, D.2    Movat, H.Z.3
  • 60
    • 0019817468 scopus 로고
    • New synthetic inhibitors of Cir, C1 esterase, thrombin, plasmin, kallikrein and trypsin
    • Fujii S, Hitomi Y: New synthetic inhibitors of Cir, C1 esterase, thrombin, plasmin, kallikrein and trypsin. Biochim Biophys Acta 1981;661:342-345.
    • (1981) Biochim Biophys Acta , vol.661 , pp. 342-345
    • Fujii, S.1    Hitomi, Y.2
  • 63
    • 0028127461 scopus 로고
    • Pancreatic microcirculatory changes in experimental pancreatitis of graded severity in the rat
    • Knoefel WT, Kollias N, Warshaw AL, Waldner H, Nishioka NS, Rattner DW: Pancreatic microcirculatory changes in experimental pancreatitis of graded severity in the rat. Surgery 1994;116:904-913.
    • (1994) Surgery , vol.116 , pp. 904-913
    • Knoefel, W.T.1    Kollias, N.2    Warshaw, A.L.3    Waldner, H.4    Nishioka, N.S.5    Rattner, D.W.6
  • 64
    • 0034230778 scopus 로고    scopus 로고
    • Characterization and prevention of phototoxic effects in intravital fluorescence microscopy in the hamster dorsal skinfold model
    • Steinbauer M, Harris AG, Abels C, Messmer K: Characterization and prevention of phototoxic effects in intravital fluorescence microscopy in the hamster dorsal skinfold model. Langenbecks Arch Surg 2000;385:290-298.
    • (2000) Langenbecks Arch Surg , vol.385 , pp. 290-298
    • Steinbauer, M.1    Harris, A.G.2    Abels, C.3    Messmer, K.4
  • 65
    • 0031002858 scopus 로고    scopus 로고
    • Intravital fluorescence microscopy: Impact of light-induced phototoxicity on adhesion of fluorescently labeled leukocytes
    • Saetzler RK, Jallo J, Lehr HA, Philips CM, Vasthare U, Arfors KE, Tuma RF: Intravital fluorescence microscopy: impact of light-induced phototoxicity on adhesion of fluorescently labeled leukocytes. J Histochem Cytochem 1997;45:505-513.
    • (1997) J Histochem Cytochem , vol.45 , pp. 505-513
    • Saetzler, R.K.1    Jallo, J.2    Lehr, H.A.3    Philips, C.M.4    Vasthare, U.5    Arfors, K.E.6    Tuma, R.F.7
  • 66
    • 0034902166 scopus 로고    scopus 로고
    • Regional effects of Nafamostat, a novel potent protease and complement inhibitor, on severe necrotizing pancreatitis
    • Keck T, Balcom J, Antoniu B, Lewandrowski K, Warshaw AL, Fernandez-del-Castillo C: Regional effects of Nafamostat, a novel potent protease and complement inhibitor, on severe necrotizing pancreatitis. Surgery 2001;130: 175-181.
    • (2001) Surgery , vol.130 , pp. 175-181
    • Keck, T.1    Balcom, J.2    Antoniu, B.3    Lewandrowski, K.4    Warshaw, A.L.5    Fernandez-del-Castillo, C.6
  • 68
    • 0029915798 scopus 로고    scopus 로고
    • Continuous regional arterial infusion of protease inhibitor and antibiotics in acute necrotizing pancreatitis
    • Takeda K, Matsuno S, Sunamura M, Kakugawa Y: Continuous regional arterial infusion of protease inhibitor and antibiotics in acute necrotizing pancreatitis. Am J Surg 1996;171:394-398.
    • (1996) Am J Surg , vol.171 , pp. 394-398
    • Takeda, K.1    Matsuno, S.2    Sunamura, M.3    Kakugawa, Y.4
  • 69
    • 0027367644 scopus 로고
    • Gabexate mesilate vs. aprotinin in human acute pancreatitis (GA.ME.P.A.). A prospective, randomized, double-blind multicenter study
    • Pederzoli P, Cavallini G, Falconi M, Bassi C: Gabexate mesilate vs. aprotinin in human acute pancreatitis (GA.ME.P.A.). A prospective, randomized, double-blind multicenter study. Int J Pancreatol 1993;14:117-124.
    • (1993) Int J Pancreatol , vol.14 , pp. 117-124
    • Pederzoli, P.1    Cavallini, G.2    Falconi, M.3    Bassi, C.4
  • 71
    • 0029788508 scopus 로고    scopus 로고
    • Gabexate for the prevention of pancreatic damage related to endoscopic retrograde cholangiopancreatography
    • Gabexate in digestive endoscopy-Italian Group
    • Cavallini G, Tittobello A, Frulloni L, Masci E, Mariana A, Di F, V: Gabexate for the prevention of pancreatic damage related to endoscopic retrograde cholangiopancreatography. Gabexate in digestive endoscopy-Italian Group. N Engl J Med 1996;335:919-923.
    • (1996) N Engl J Med , vol.335 , pp. 919-923
    • Cavallini, G.1    Tittobello, A.2    Frulloni, L.3    Masci, E.4    Mariana, A.5    Di, F.V.6
  • 72
    • 18344404181 scopus 로고    scopus 로고
    • Gabexate or somatostatin administration before ERCP in patients at high risk for post-ERCP pancreatitis: A multicenter, placebo-controlled, randomized clinical trial
    • Andriulli A, Clemente R, Solmi L, Terruzzi V, Suriani R, Sigillito A, Leandro G, Leo P, De Maio G, Perri F: Gabexate or somatostatin administration before ERCP in patients at high risk for post-ERCP pancreatitis: A multicenter, placebo-controlled, randomized clinical trial. Gastrointest Endosc 2002;56:488-495.
    • (2002) Gastrointest Endosc , vol.56 , pp. 488-495
    • Andriulli, A.1    Clemente, R.2    Solmi, L.3    Terruzzi, V.4    Suriani, R.5    Sigillito, A.6    Leandro, G.7    Leo, P.8    De Maio, G.9    Perri, F.10


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