Dysregulation of hedgehog sinalling predisposes to synovial chondromatosis

Journal of Pathology

Volumn 206, Issue 2, 2005, Pages 143-150

  Hopyan, Sevan ^a,b,c   Nadesan, Puviindran ^a   Yu, Chunying ^a   Wunder, Jay ^b,c   Alman, Benjamin A ^a,c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Chondrocytes; Gli genes; Hedgehog; Immunohistochemistry; Mouse models; Synovial chondromatosis; Synovium; Triparanol

Indexed keywords

PROTEIN PATCHED 1; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRIPARANOL; CARRIER PROTEIN; DNA BINDING PROTEIN; GLI PROTEIN; GLI3 PROTEIN, MOUSE; HHIP PROTEIN, HUMAN; HHIP PROTEIN, MOUSE; KRUPPEL LIKE FACTOR; MEMBRANE PROTEIN; NERVE PROTEIN; ONCOPROTEIN; PROTEIN TYROSINE KINASE; RET PTC FUSION ONCOPROTEINS, HUMAN; RET-PTC FUSION ONCOPROTEINS, HUMAN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTHRALGIA; ARTHROPATHY; ARTICLE; CASE REPORT; CHONDROMATOSIS; CONTROLLED STUDY; DATA ANALYSIS; DISEASE PREDISPOSITION; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; JOINT DESTRUCTION; MALE; MOUSE; MOUSE MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; SYNOVIUM; WILD TYPE; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSACTIVATION;

ANIMALS; CARRIER PROTEINS; CHONDROMATOSIS, SYNOVIAL; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, MUTANT STRAINS; MUTATION; NERVE TISSUE PROTEINS; ONCOGENE PROTEINS; ONCOGENE PROTEINS, FUSION; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRIPARANOL;

EID: 19944376873     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1761     Document Type: Article

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