Production of endothelin-1 and big endothelin-1 by human cardiac myxoma cells - Implications for the origin of myxomas

Circulation Journal

Volumn 68, Issue 12, 2004, Pages 1230-1232

  Sakamoto, Hironosuke ^a   Sakamaki, Tetsuo ^a   Sumino, Hiroyuki ^a   Sawada, Yoshie ^a   Sato, Hiroko ^a   Sato, Mahito ^a   Fujita, Kin'ichi ^a   Kanda, Tsugiyasu ^b   Tamura, Jun'ichi ^a   Kurabayashi, Masahiko ^a  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

Cardiac myxoma; Endothelin 1; Growth related oncogene

Indexed keywords

ALPHA CHEMOKINE; BIG ENDOTHELIN 1; CYTOKINE; ENDOTHELIN 1; ENDOTHELIN 3; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 6; INTERLEUKIN 8; SCATTER FACTOR; STEM CELL FACTOR;

ADULT; ARTICLE; BENIGN TUMOR; CASE REPORT; CELL DIFFERENTIATION; CONCENTRATION (PARAMETERS); CULTURE MEDIUM; CYTOKINE PRODUCTION; ENDOCARDIUM; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GROWTH RELATED ONCOGENE ALPHA; HEART MYXOMA; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; MESENCHYME CELL; NERVOUS TISSUE; ONCOGENE; TUMOR CELL; UMBILICAL VEIN;

ADULT; CELL LINE, TUMOR; CELLS, CULTURED; CULTURE MEDIA; ENDOTHELIAL CELLS; ENDOTHELIN-1; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEART NEOPLASMS; HUMANS; MIDDLE AGED; MYXOMA; UMBILICAL VEINS;

EID: 19944368395     PISSN: 13469843     EISSN: None     Source Type: Journal    
DOI: 10.1253/circj.68.1230     Document Type: Article

References (12)

1. Pucci A, Gagliardotto P, Zanini C, Pansini S, di Summa M, Mollo F. Histopathologic and clinical characterization of cardiac myxoma: Review of 53 cases from a single institution. Am Heart J 2000; 140: 134-138.
2. Krikler DM, Rode J, Davies MJ, Woolf N, Moss E. Atrial myxoma: A tumour in search of its origins. Br Heart J 1992; 67: 89-91.
3. Hirano T, Taga T, Yasukawa K, Nakashima K, Nakano N, Takatsuki F, et al. Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production. Proc Natl Acad Sci USA 1987; 84: 228-231.
4. Sakamoto H, Sakamaki T, Kanda T, Hirao Y, Ohyama Y, Ogishi K, et al. Immunosuppressive drugs inhibit the production of interleukin-6 and interleukin-8 in cultured cardiac myxoma cells. Res Commun Mol Pathol Pharmacol 1997; 97: 60-66.
5. Zhang T, Koide N, Wada Y, Tsukioka K, Takayama K, Kono T, et al. Significance of monocyte chemotactic protein-1 and thymidine phosphorylase in angiogenesis of human cardiac myxoma. Circ J 2003; 67: 54-60.
6. Sakamoto H, Sakamaki T, Kanda T, Tsuchiya Y, Sato M, Sato H, et al. Vascular endothelial growth factor is an autocrine growth factor for cardiac myxoma cells. Circ J 2004; 68: 488-493.
7. Baggiolini M, Dewald B, Moser B. Interleukin-8 and related chemotactic cytokines: CXC and CC chemokines. Adv Immunol 1994; 55: 97-179.
8. Wada A, Kanda T, Hayashi R, Imai S, Suzuki T, Murata K. Cardiac myxoma metastasized to the brain: Potential role of endogenous interleukin-6. Cardiology 1993; 83: 208-211.
9. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332: 411-415.
10. Miyauchi T, Masaki T. Pathophysiology of endothelin in the cardiovascular system. Annu Rev Physiol 1999; 61: 391-415.
11. Krishnaswamy G, Kelley J, Yerra L, Smith JK, Chi DS. Human endothelium as a source of multifunctional cytokines: Molecular regulation and possible role in human disease. J Interferon Cytokine Res 1999; 19: 91-104.
12. Bocci G, Fasciani A, Danesi R, Viacava P, Genazzani AR, Tacca MD. In-vitro evidence of autocrine secretion of vascular endothelial growth factor by endothelial cells from human placental blood vessels. Mol Hum Reprod 2001; 7: 771-777.