Neurohormonal determinants of peak oxygen uptake in patients with chronic heart failure

Japanese Heart Journal

Volumn 44, Issue 5, 2003, Pages 725-734

  Kinugawa, Toru ^a   Kato, Masahiko ^a   Ogino, Kazuhide ^a   Igawa, Osamu ^a   Hisatome, Ichiro ^a   Shigemasa, Chiaki ^a   Nohara, Ryuji ^b  

^a TOTTORI UNIVERSITY   (Japan)

^b Kitano Hospital   (Japan)

Author keywords

Cardiopulmonary exercise test; Cytokines; Heart failure; Neurohormones; Peak oxygen uptake

Indexed keywords

ADRENALIN; ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; CYTOKINE; INTERLEUKIN 6; NEUROHORMONE; NORADRENALIN; OXYGEN; TUMOR NECROSIS FACTOR ALPHA;

ADRENALIN BLOOD LEVEL; ADULT; AGE DISTRIBUTION; ARTICLE; BICYCLE ERGOMETRY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NORADRENALIN BLOOD LEVEL; OXYGEN CONSUMPTION; PREDICTION; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

ATRIAL NATRIURETIC FACTOR; CHRONIC DISEASE; CYTOKINES; EXERCISE TEST; FEMALE; HEART FAILURE, CONGESTIVE; HUMANS; INTERLEUKIN-6; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NATRIURETIC PEPTIDE, BRAIN; NEUROTRANSMITTER AGENTS; NOREPINEPHRINE; OXYGEN CONSUMPTION; RENIN-ANGIOTENSIN SYSTEM; TUMOR NECROSIS FACTOR-ALPHA;

EID: 19844382043     PISSN: 00214868     EISSN: 1348673X     Source Type: Journal    
DOI: 10.1536/jhj.44.725     Document Type: Article

References (30)

1. Schrier RW, Abraham WT. Hormones and hemodynamics in heart failure. N Engl J Med 1999; 341: 577-85.
2. Baumgarten G, Knuefermann, Mann DL. Cytokines as emerging targets in the treatment of heart failure. Trends Cardiovasc Med 2000; 10: 216-23.
3. Francis GS, Cohn JN, Johnson G, Rector TS, Goldman S, Simon A, for the V-HeFT VA Cooperative Studies Group. Plasma norepinephrine, plasma renin activity, and congestive heart failure. Relationship to survival and the effects of therapy in V-HeFT II. Circulation 1993; 87: VI-40.
4. Cowie MR, Struthers AD, Wood DA, et al. Value of natriuretic peptides in assessment of patients with possible new heart failure. Lancet 1997; 350: 1349-53.
5. Gottlieb SS, Kukin ML, Ahern D, Packer M. Prognostic importance of atrial natriuretic peptide in patients with chronic heart failure. J Am Coll Cardiol 1989; 13: 1534-9.
6. Tsutamoto T, Wada A, Maeda K, et al. Attenuation of compensation of endogenous cardiac natriuretic peptide system in chronic heart failure: Prognostic role of plasma brain natriuretic peptide concentration in patients with chronic symptomatic left ventricular dysfunction. Circulation 1997; 96: 509-16.
7. Mann DL. Recent insights into the role of tumor necrosis factor in the failing heart. Heart Failure Reviews 2000; 6: 71-80.
8. Wollert KC, Drexler H. The role of interleukin-6 in the failing heart. Heart Failure Reviews 2001; 6: 95-103.
9. Mancini DM, Eisen H, Kussmaul W, Mull R, Edmunds LH, Jr., Wilson JR. Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure. Circulation 1991; 83: 778-86.
10. Myers J, Gullestad L, Vagelos R Vagelos R, Do D, Bellin D, et al. Clinical, hemodynamic, and cardiopulmonary exercise test determinants of survival in patients referred for evaluation of heart failure. Ann Intern Med 1998; 129: 286-93.
11. Opasich C, Pinna GD, Bobbio M, et al. Peak exercise oxygen consumption in chronic heart failure: toward efficient use in the individual patient. J Am Coll Cardiol 1998; 31: 766-75.
12. Myers J, Gullestad L, Vagelos R, et al. Cardiopulmonary exercise testing and prognosis in severe heart failure: 14 mg/kg/min revisited. Am Heart J 2000; 139: 78-84.
13. 2; a simple yet enduring standard. Circulation 2000; 101: 1080-2.
14. Pardaens K, Cleemput V, Vanhaecke J, Fagard RH. Peak oxygen uptake better predicts outcome than submaximal respiratory data in heart transplant candidates. Circulation 2000; 101: 1152-7.
15. Teichholz LE, Kreulen T, Herman MV, Gorlin R. Problems in echocardiographic volume determinations: Echocardiographic-angiographic correlations in the presence or absence of asynergy. Am J Cardiol 1976; 37: 7-11.
16. Kinugawa T, Kato M, Mori M, et al. Effects of a new angiotensin-converting enzyme inhibitor, alacepril, on changes in neurohormonal factors and arterial baroreflex sensitivity in patients with congestive heart failure. Eur J Clin Pharmacol 1998; 54: 209-14.
17. Kinugawa T, Kato M, Ogino K, et al. Interleukin-6 and tumor necrosis factor-α levels increase in response to maximal exercise in patients with chronic heart failure. Int J Cardiol 2003; 87: 83-90.
18. Sue DY, Wasserman K, Morrica RB, Casaburi R. Measurement of anaerobic threshold by V-slope method in patients with chronic obstructive lung disease and normal subjects. Chest 1988; 94: 931-8.
19. Colluci WS, Ribeiro JP, Rocco MB, et al. Impaired chronotropic response to exercise in patients with congestive heart failure: role of postsynaptic β-adrenergic desensitization. Circulation 1989; 80: 314-23.
20. Francis GS, Goldsmith SR, Cohn JN. Relationship of exercise capacity to resting left ventricular performance and basal plasma norepinephrine levels in patients with congestive heart failure. Am Heart J 1982; 104: 725-31.
21. Kraemer MD, Kubo SH, Rector TS, Brunsvold N, Bank AJ. Pulmonary and peripheral vascular factors are important determinants of peak exercise oxygen uptake in patients with heart failure. J Am Coll Cardiol 1993; 21: 641-8.
22. Notarius CF, Ando S, Rongen GA, Floras JS. Resting muscle sympathetic nerve activity and peak oxygen uptake in heart failure and normal subjects. Eur Heart J 1990; 20: 880-7.
23. Harrington D, Coats AJS. Mechanisms of exercise intolerance in congestive heart failure. Curr Opin Cardiol 1997; 12: 224-32.
24. McMurray JJ, Ray SG, Abdullah I, Dargie HJ, Morton JJ. Plasma endothelin in chronic heart failure. Circulation 1992; 85: 1374-9.
25. Raine AEG, Erne P, Bürgisser E, Müller FB, Bolli P, Burkart F. Atrial natriuretic peptide and atrial pressure in patients with congestive heart failure. N Engl J Med 1986; 315: 533-7.
26. Kao A, Goldberg L, Liang BT, Li RH, Holmes EW, Loh E. Atrial natriuretic peptide levels predict exercise capacity in patients with heart failure. Circulation 2000; 102: II-759.
27. Kruger S, Graf J, Kunz D, Stickel T, Hanrath P, Janssens U. Brain natriuretic peptide levels predict functional capacity in patients with chronic heart failure. J Am Coll Cardiol 2002; 40: 718-22.
28. Hulsmann M, Stanek B, Frey B, et al. Value of cardiopulmonary exercise testing and big endothelin plasma levels to predict short-term prognosis of patients with chronic heart failure. J Am Coll Cardiol 1998; 32: 1695-700.
29. Isnard R, Pousset F, Trochu J, et al. Prognostic value of neurohormonal activation and cardiopulmonary exercise testing in patients with chronic heart failure. Am J Cardiol 2000; 86: 417-21.
30. 2 is more potent than brain natriuretic peptide (BNP) as a prognostic parameter in cardiac patients. Eur Heart J 2002; 23: 78.