Malignant hyperthermia in a horse anesthetized with halothane

Journal of Veterinary Internal Medicine

Volumn 19, Issue 3, 2005, Pages 363-367

  Aleman, Monica ^a   Brosnan, Robert J ^a   Williams, D Colette ^a   LeCouteur, Richard A ^a   Imai, Ayako ^a   Tharp, Barry R ^b   Steffey, Eugene P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETIC AGENT; HALOTHANE;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL VENTILATION; ELECTROENCEPHALOGRAM; ELECTROMYOGRAM; ELECTROOCULOGRAM; HORSE; LUNG MINUTE VOLUME; MALE; MALIGNANT HYPERTHERMIA; MINIMUM LUNG ALVEOLUS CONCENTRATION; MYELITIS; NONHUMAN; PERONEUS NERVE;

ANIMALIA; EQUUS CABALLUS;

EID: 19744378069     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1892/0891-6640(2005)19[363:MHIAHA]2.0.CO;2     Document Type: Article

References (23)

1. Steffey EP, Howland D Jr. Comparison of circulatory and respiratory effects of isoflurane and halothane anesthesia in horses. Am J Vet Res 1980;41:821-825.
2. Denborough M. Malignant hyperthermia. Lancet 1998;352:1131-1136.
3. McCarthy TV, Healy JM, Heffron JJ, et al. Localization of the malignant hyperthermia susceptibility locus to human chromosome 19q12-13.2. Nature 1990;343:562-564.
4. Fujii J, Otsu K, Zorzato F, et al. Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia. Science 1991;253:448-451.
5. Roberts MC, Mickelson JR, Patterson EE, et al. Autosomal dominant canine malignant hyperthermia is caused by a mutation in the gene encoding the skeletal muscle calcium release channel (RYR1). Anesthesiology 2001;95:716-725.
6. Hildebrand SV, Howitt GA. Succinylcholine infusion associated with hyperthermia in ponies anesthetized with halothane. Am J Vet Res 1983;44:2280-2284.
7. Hildebrand SV, Arpin D, Howitt GA, et al. Muscle biopsy to differentiate normal from suspected malignant hyperthermia horses and ponies. Vet Surg 1988;17:172-173.
8. Hildebrand SV, Arpin D, Cardinet G III. Contracture test and histologic and histochemical analyses of muscle biopsy specimens from horses with exertional rhabdomyolysis. J Am Vet Med Assoc 1990;196:1077-1083.
9. Klein LV. A hot horse. Vet Anesth 1975;2:41-42.
10. Manley SV, Kelly AB, Hodgson D. Malignant hyperthermia-like reactions in three anesthetized horses. J Am Vet Med Assoc 1983;183:85-89.
11. Riedesel DH, Hildebrand SV. Unusual response following use of succinylcholine in a horse anesthetized with halothane. J Am Vet Med Assoc 1985;187:507-508.
12. Waldron-Mease E, Rosenberg H. Post anesthetic myositis in the horse associated with in vitro malignant hyperthermia susceptibility. Vet Sci Commun 1979;3:45-50.
13. Waldron-Mease E, Klein LV, Rosenberg H, et al. Malignant hyperthermia in a halothane-anesthetized horse. J Am Vet Med Assoc 1981;179:896-898.
14. Smyth GB. Spinal cord decompression and stabilization of a comminuted axis fracture complicated by intraoperative malignant hyperthermia like reaction in a filly. Aust Equine Vet 1992;10:133-136.
15. Klein L, Ailes N, Fackelman GE, et al. Postanesthetic equine myopathy suggestive of malignant hyperthermia. A case report. Vet Surg 1989;18:479-482.
16. Aleman M, Riehl J, Aldridge BM, et al. Association of a mutation in the ryanodine receptor 1 gene with equine malignant hyperthermia. Muscle Nerve 2004;30:356-365.
17. Brandt A, Schleithoff L, Jurkat-Rott K, et al. Screening of the ryanodine receptor gene in 105 malignant hyperthermia families: Novel mutations and concordance with the in vitro contracture test. Hum Mol Genet 1999;8:2055-2062.
18. Johnston GM, Eastment JK, Taylor PM, et al. Is isoflurane safer than halothane in equine anaesthesia? Results from a prospective multicentre randomised controlled trial. Equine Vet J 2004;36:64-71.
19. Cornick JL, Seahorn TL, Hartsfield SM. Hyperthermia during isoflurane anaesthesia in a horse with suspected hyperkalemic periodic paralysis. Equine Vet J 1994;26:511-514.
20. Moslehi R, Langlois S, Yam I, et al. Linkage of malignant hyperthermia and hyperkalemic periodic paralysis to the adult skeletal muscle sodium channel (SCN4A) gene in a large pedigree. Am J Med Genet 1998;76:21-27.
21. Rajabally YA, El Lahawi M. Hypokalemic periodic paralysis associated with malignant hyperthermia. Muscle Nerve 2002;25:453-455.
22. Kochs E, Hoffman WE, Roewer N, et al. Alterations in brain electrical activity may indicate the onset of malignant hyperthermia in swine. Anesthesiology 1990;73:1236-1242.
23. Chatrian GE, Turella GS. Electrophysiological evaluation of coma, other states of diminished responsiveness and brain death. In: Ebersole JS, Pedley TA, eds. Current Practice of Clinical Electroencephalography, 3rd ed. Philadelphia, PA: Lippicott, Williams & Wilkins; 2003:405-462.