Identification of surface antigens of Moraxella catarrhalis as targets of human serum antibody responses in chronic obstructive pulmonary disease

Infection and Immunity

Volumn 73, Issue 6, 2005, Pages 3471-3478

  Murphy, Timothy F ^a,b,c   Brauer, Aimee L ^a,c   Aebi, Christoph ^d   Sethi, Sanjay ^b,c  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c VA WESTERN NEW YORK HEALTHCARE SYSTEM   (United States)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL; ERYTHROMYCIN; IMMUNOGLOBULIN G; KANAMYCIN; LIPOOLIGOSACCHARIDE; MEMBRANE ANTIGEN; MONOCLONAL ANTIBODY; OUTER MEMBRANE PROTEIN;

ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY RESPONSE; ARTICLE; BLOOD SAMPLING; CHILD; CHRONIC OBSTRUCTIVE LUNG DISEASE; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALE; MORAXELLA CATARRHALIS; MORAXELLACEAE INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT INFECTION; STRAIN DIFFERENCE;

ADSORPTION; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; ANTIGENS, SURFACE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOBLOTTING; LIPOPOLYSACCHARIDES; MORAXELLA (BRANHAMELLA) CATARRHALIS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 19744362275     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.6.3471-3478.2005     Document Type: Article

References (26)

1. American Thoracic Society. 1995. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 152:S77-S121.
2. Bakri, F., A. L. Brauer, S. Sethi, and T. F. Murphy. 2002. Systemic and mucosal antibody response to Moraxella catarrhalis following exacerbations of chronic obstructive pulmonary disease. J. Infect. Dis. 185:632-640.
3. Campagnari, A. A., T. F. Ducey, and C. A. Rebmann. 1996. Outer membrane protein B1, an iron-repressible protein conserved in the outer membrane of Moraxella (Branhamella) catarrhalis, binds human transferrin. Infect. Immun. 64:3920-3924.
4. Chen, D., V. Barniak, K. R. van der Meid, and J. C. McMichael. 1999. The levels and bactericidal capacity of antibodies directed against the UspA1 and UspA2 outer membrane proteins of Moraxella (Branhamella) catarrhalis in adults and children. Infect. Immun. 67:1310-1316.
5. Christensen, J. J., N. Q. Hansen, and B. Bruun. 1996. Serum antibody response to outer membrane proteins of Moraxella (Branhamella) catarrhalis in patients with bronchopulmonary infection. Clin. Diagn. Lab. Immunol. 3:717-721.
6. Gump, D. W., C. A. Phillips, B. R. Forsyth, F. K. McIntosh, K. R. Lamborn, and W. H. Stouch. 1976. Role of infection in chronic bronchitis. Am. Rev. Respir. Dis. 113:465-473.
7. Hill, A. T., E. J. Campbell, S. L. Hill, D. L. Bayley, and R. A. Stockley. 2000. Association between airway bacterial load and markers of airway inflammation in patients with stable chronic bronchitis. Am. J. Med. 109:288-295.
8. Mathers, K., M. Leinonen, and D. Goldblatt. 1999. Antibody response to outer membrane proteins of Moraxella catarrhalis in children with otitis media. Pediatr. Infect. Dis. J. 18:982-988.
9. May, J. R. 1953. The bacteriology of chronic bronchitis. Lancet 12:534-537.
10. McHardy, V. U., J. M. Inglis, M. A. Calder, and J. W. Crofton. 1980. A study of infective and other factors in exacerbations of chronic bronchitis. Br. J. Dis. Chest 74:228-238.
11. Meier, P. S., S. Freiburghaus, A. Martin, N. Heiniger, R. Troller, and C. Aebi. 2003. Mucosal immune response to specific outer membrane proteins of Moraxella catarrhalis in young children. Pediatr. Infect. Dis. J. 22:256-262.
12. Monso, E., J. Ruiz, A. Rosell, J. Manterola, J. Fiz, J. Morera, and V. Ausina. 1995. Bacterial infection in chronic obstructive pulmonary disease. A study of stable and exacerbated outpatients using the protected specimen brush. Am. J. Respir. Crit. Care Med. 152:1316-1320.
13. Murphy, T. F., and L. C. Bartos. 1989. Surface-exposed and antigenically conserved determinants of outer membrane proteins of Branhamella catarrhalis. Infect. Immun. 57:2938-2941.
14. Murphy, T. F., C. Kirkham, D. F. Liu, and S. Sethi. 2003. Human immune response to outer membrane protein CD of Moraxella catarrhalis in adults with chronic obstructive pulmonary disease. Infect. Immun. 71:1288-1294.
15. Murphy, T. F., A. L. Brauer, B. J. B. Grant, and S. Sethi. Moraxella catarrhalis in chronic obstructive pulmonary disease: burden of disease and immune response. Am. J. Respir. Crit. Care Med., in press.
16. Myers, L. E., Y.-P. Yang, R.-P. Du, Q. Wang, R. E. Harkness, A. B. Schryvers, M. H. Klein, and S. M. Loosmore. 1998. The transferrin binding protein B of Moraxella catarrhalis elicits bactericidal antibodies and is a potential vaccine antigen. Infect. Immun. 66:4183-4192.
17. Pauwels, R. A., A. S. Buist, P. M. Calverley, C. R. Jenkins, and S. S. Hurd. 2001. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am. J. Respir. Crit. Care Med. 163:1256-1276.
18. Sethi, S., N. Evans, B. J. B. Grant, and T. F. Murphy. 2002. New strains of bacteria and exacerbations of chronic obstructive pulmonary disease. N. Engl. J. Med. 347:465-471.
19. Sethi, S., S. L. Hill, and T. F. Murphy. 1995. Serum antibodies to outer membrane proteins (OMPs) of Moraxella (Branhamella) catarrhalis in patients with bronchiectasis: identification of OMP B1 as an important antigen. Infect. Immun. 63:1516-1520.
20. Sethi, S., and T. F. Murphy. 2001. Bacterial infection in chronic obstructive pulmonary disease in 2000: a state-of-the-art review. Clin. Microbiol. Rev. 14:336-363.
21. Smith, C. B., C. Golden, M. R. Klauber, R. Kanner, and A. Renzetti. 1976. Interactions between viruses and bacteria in patients with chronic bronchitis. J. Infect. Dis. 134:552-561.
22. Soler, N., S. Ewig, A. Torres, X. Filella, J. Gonzalez, and A. Zaubet. 1999. Airway inflammation and bronchial microbial patterns with stable chronic obstructive pulmonary disease. Eur. Respir. J. 14:1015-1022.
23. Stutzmann Meier, P., N. Heiniger, R. Troller, and C. Aebi. 2003. Salivary antibodies directed against outer membrane proteins of Moraxella catarrhalis in healthy adults. Infect. Immun. 71o:6793-6798.
24. Wilson, R. 1998. The role of infection in COPD. Chest 113:2428-2488.
25. Yu, R.-H., R. A. Bonnah, S. Ainsworth, and A. B. Schryvers. 1999. Analysis of the immunological responses to transferrin and lactoferrin receptor proteins from Moraxella catarrhalis. Infect. Immun. 67:3793-3799.
26. Zalacain, R., V. Sobradillo, J. Amilibia, J. Barron, V. Achotegui, J. I. Pijoan, and J. L. Llorente. 1999. Predisposing factors to bacterial colonization in chronic obstructive pulmonary disease. Eur. Respir. J. 13:343-348.