Paraprotein interference in automated chemistry analyzers [6]

Clinical Chemistry

Volumn 51, Issue 6, 2005, Pages 1077-1078

  Sheppard, Chelsea A ^a,b   Allen, Robert C ^a,c   Austin, Garth E ^a,d   Young, Andrew N ^a,d   Ribeiro, Maria A ^b,d   Fantz, Corinne R ^a  

^a Departments of Pathology and Laboratory Medicine   (United States)

^b EMORY UNIVERSITY HOSPITAL   (United States)

^c GRADY MEMORIAL HOSPITAL   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; IMMUNOGLOBULIN M; PARAPROTEIN;

AUTOANALYZER; AUTOMATION; BILIRUBIN BLOOD LEVEL; BLOOD SAMPLING; HUMAN; IMMUNOASSAY; LETTER; MULTIPLE MYELOMA; NEPHELOMETRY; PRECIPITATION; REFERENCE VALUE; TURBIDIMETRY;

ARTIFACTS; AUTOANALYSIS; BILIRUBIN; FALSE POSITIVE REACTIONS; HUMANS; PARAPROTEINS;

EID: 19644386499     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2004.045740     Document Type: Letter

References (8)

1. Smogorzewska A, Flood JG, Long WH, Dighe AS. Paraprotein interference in automated chemistry analyzers [Technical Brief]. Clin Chem 2004;50:1691-3.
2. Yamada K, Yagihashi A, Ishii S, Tanemura K, Kida T, Watanabe N, et al. Interference with nephelometric assay of C-reactive protein and antistreptolysin-O by monoclonal IgM-κ from a myeloma patient. Clin Chem 1997;43:2435-7.
3. Cohen AM, Magazanik A, van-der Lijn E, Shaked P, Levinsky H. Pseudohyperphosphatemic incidence in an automatic analyzer. Eur J Clin Chem Clin Biochem 1994;32:559-61.
4. Bowles SA, Tait RC, Jefferson SG, Gilleece MH, Haeney MR. Characteristics of monoclonal immunoglobulins that interfere with serum inorganic phosphate measurement. Ann Clin Biochem 1994;31:249-54.
5. John R, Pleesky D, Issa B, Scanlon MF, Williams CP, Harrison CB, et al. Pseudohypercalcemia in two patients with IgM paraproteinaemia. Ann Clin Biochem 1997;34:694-6.
6. Westwood A. The analysis of bilirubin in serum. Ann Clin Biochem 1991;28:119-30.
7. Roche Diagnostics. Total bilirubin [Package Insert]. Indianapolis. IN: Roche Diagnostics, 2001.
8. Pantanowitz L, Horowitz GL, Upalakalin JN, Beckwith BA. Artifactual hyperbilirubinemia due to paraprotein interference. Arch Pathol Lab Med 2003;127:55-9.