Characterization and optimization of acoustic filter performance by experimental design methodology

Biotechnology and Bioengineering

Volumn 90, Issue 6, 2005, Pages 746-753

  Gorenflo, Volker M ^a,b,d   Ritter, Joachim B ^a,c   Aeschliman, Dana S ^a,b   Drouin, Hans ^a,b   Bowen, Bruce D ^b   Piret, James M ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c MAX PLANCK INSTITUTE FOR DYNAMICS OF COMPLEX TECHNICAL SYSTEMS   (Germany)

^d Sanofi Pasteur   (Canada)

Author keywords

Cell retention; Chinese hamster ovary (CHO); Continuous; Factorial; Fractional; Mammalian cell culture; Model; Perfusion; Response surface; Separation; Separator; Statistics

Indexed keywords

BIOREACTORS; CELL CULTURE; CELLS; DATA ACQUISITION; FOULING; MATHEMATICAL MODELS; MAXIMUM LIKELIHOOD ESTIMATION; OPTIMIZATION; SEPARATION;

CELL RETENTION SYSTEMS; PERFUSION RATES; RECIRCULATION RATIO; SEPARATION EFFICIENCY;

ACOUSTIC DEVICES;

ANIMAL CELL; ARTICLE; BIOREACTOR; CELL CULTURE; CELL SEPARATION; EXPERIMENTAL DESIGN; FACTORIAL ANALYSIS; MAMMAL CELL; MEMBRANE FILTER; METHODOLOGY; NONHUMAN; PERFUSION; SEPARATION TECHNIQUE;

ACOUSTICS; ANIMALS; CELL SEPARATION; CHO CELLS; COMPUTER SIMULATION; COMPUTER-AIDED DESIGN; CRICETINAE; CRICETULUS; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; MICROFLUIDICS; MODELS, BIOLOGICAL; ULTRAFILTRATION;

CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

EID: 19644384700     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20476     Document Type: Article

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