Interaction between the T4 helicase loading protein (gp59) and the DNA polymerase (gp43): Unlocking of the gp59-gp43-DNA complex to initiate assembly of a fully functional replisome

Biochemistry

Volumn 44, Issue 21, 2005, Pages 7747-7756

  Xi, Jun ^a   Zhang, Zhiquan ^b   Zhuang, Zhihao ^a   Yang, Jingsong ^a   Spiering, Michelle M ^a   Hammes, Gordon G ^b   Benkovic, Stephen J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA REPLICATION SYSTEM; EXONUCLEASE ACTIVITIES; FUNCTIONAL PRIMOSOME; HELICASE LOADING PROTEINS;

BACTERIA; COMPLEXATION; DISSOCIATION; DNA; ENZYMES; ORGANIC POLYMERS; SYNTHESIS (CHEMICAL);

PROTEINS;

DNA BINDING PROTEIN; DNA POLYMERASE; EXONUCLEASE; HELICASE; OKAZAKI FRAGMENT; REPLISOME;

ARTICLE; BACTERIOPHAGE T4; DNA BINDING; DNA REPLICATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; PRIORITY JOURNAL; PROTEIN INTERACTION;

BACTERIOPHAGE T4; DNA HELICASES; DNA PRIMASE; DNA REPLICATION; DNA, VIRAL; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HOLOENZYMES; MICROSCOPY, FLUORESCENCE; MULTIENZYME COMPLEXES; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; SUBSTRATE SPECIFICITY; VIRAL PROTEINS; VIRUS ASSEMBLY; VIRUS REPLICATION;

EID: 19644375053     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi047296w     Document Type: Article

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