Novel spiro-quinone formation from 3′-hydroxydiethylstilbestrol after oxidation with silver oxide

Tetrahedron Letters

Volumn 46, Issue 26, 2005, Pages 4449-4451

  Saeed, Muhammad ^a   Rogan, Eleanor ^a   Cavalieri, Ercole ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Catechol estrogen; Depurinating adducts; Diethylstilbestrol; Oxidation; spiro Quinone

Indexed keywords

3' HYDROXYDIETHYLSTILBESTROL; CARCINOGEN; CATECHOL; DIETHYLSTILBESTROL DERIVATIVE; HYDROXIDE; PHENOL DERIVATIVE; QUINONE DERIVATIVE; SILVER DERIVATIVE; SILVER OXIDE; UNCLASSIFIED DRUG;

ARTICLE; METABOLISM; OXIDATION; QUANTITATIVE ANALYSIS; QUANTUM YIELD;

EID: 19544394051     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.04.131     Document Type: Article

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16. 2O (6 mmol, Aldrich Chemical Co.) was added. After 10 min, TLC indicated complete consumption of 1. The dark orange colored solution was filtered and the solvent was evaporated under a stream of nitrogen to afford almost pure 3
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