Functional characterization of T cells in abdominal aortic aneurysms

Immunology

Volumn 115, Issue 2, 2005, Pages 262-270

  Forester, Nerys D ^a   Cruickshank, Sheena M ^a   Scott, D Julian A ^b   Carding, Simon R ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Abdominal aortic aneurysms; T cells

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 5; INTERLEUKIN 6; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMBRANE ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ABDOMINAL AORTA ANEURYSM; ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FLOW CYTOMETRY; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATORY INFILTRATE; LYMPHOCYTE FUNCTION; MACROPHAGE; MALE; MONONUCLEAR CELL; NATURAL KILLER CELL; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE;

AGED; AGED, 80 AND OVER; AORTIC ANEURYSM, ABDOMINAL; CELL CYCLE; CELLS, CULTURED; CYTOKINES; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COOPERATION; MALE; MIDDLE AGED; MITOGENS; RECEPTORS, INTERLEUKIN-2; T-LYMPHOCYTE SUBSETS;

EID: 19544389341     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2005.02157.x     Document Type: Article

References (17)

1. Henderson EL, Geng YJ, Sukhova GK, Whittemore AD, Knox J, Libby P. Death of smooth muscle cells and expression of mediators of apoptosis by T lymphocytes in human abdominal aortic aneurysms. Circulation 1999; 99:96-104.
2. Pearce WH, Koch AE. Cellular components and features of immune response in abdominal aortic aneurysms. Ann N Y Acad Sci 1996; 800:175-85.
3. Koch AE, Haines GK, Rizzo RJ, Radosevich JA, Pope RM, Robinson PG, Pearce WH. Human abdominal aortic aneurysms. Immunophenotypic analysis suggesting an immune-mediated response. Am J Pathol 1990; 137:1199-213.
4. Halme S, Juvonen T, Laurila A, Juvonen J, Mosorin M, Saikku P, Surcel HM. Chlamydia pneumoniae reactive T lymphocytes in the walls of abdominal aortic aneurysms. Eur J Clin Invest 1999; 29:546-52.
5. Schonbeck U, Sukhova GK, Gerdes N, Libby P. T (H) 2 predominant immune responses prevail in human abdominal aortic aneurysm. Am J Pathol 2002; 161:499-506.
6. Szekanecz Z, Shah MR, Pearce WH, Koch AE. Human atherosclerotic abdominal aortic aneurysms produce interleukin (IL)-6 and interferon-gamma but not IL-2 and IL-4: the possible role for IL-6 and interferon-gamma in vascular inflammation. Agents Actions 1994; 42:159-62.
7. Newman KM, Jean-Claude J, Li H, Ramey WG, Tilson MD. Cytokines that activate proteolysis are increased in abdominal aortic aneurysms. Circulation 1994; 90:224-227.
8. Cruickshank S, Southgate J, Selby P, Trejdosiewicz L. Inhibition of T cell activation by normal human biliary epithelial cells. J Hepatol 1996; 31:1026-33.
9. Crow P, Shaw E, Earnshaw JJ, Poskitt KR, Whyman MR, Heather BP. A single normal ultrasonographic scan at age 65 years rules out significant aneurysm disease for life in men. Br J Surg 2001; 88:941-4.
10. Wallon LJ, Powell JT, Parums DV. Unrestricted usage of immunoglobulin heavy chain genes in B cells infiltrating the wall of atherosclerotic abdominal aortic aneurysms. Atherosclerosis 1997; 135:65-71.
11. Ocana E, Bohorquez JC, Perez-Requena J, Brieva JA, Rodriguez C. Characterisation of T and B lymphocytes infiltrating abdominal aortic aneurysms. Atherosclerosis 2003; 170:39-48.
12. Xiong W, Zhao Y, Prall A a al. Key roles of CD4 (+) T cells and IFN-gamma in the development of abdominal aortic aneurysms in a murine model. J Immunol 2004; 172:2607-12.
13. Stemme S, Faber B, Holm J, Wiklund O, Witztum JL, Hansson GK, Rymo L T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. Proc Natl Acad Sci USA 1995; 92:3893-7.
14. Baumann MA, Paul CC. Interleukin-5 and human B lymphocytes. Methods 1997; 11:88-97.
15. Alzona M, Jack HM, Fisher RI, Ellis TM. CD30 defines a subset of activated human T cells that produce IFN-gamma and IL-5 and exhibit enhanced B cell helper activity. J Immunol 1994; 153:2861-7.
16. Juvonen J, Surcel HM, Satta J et al. Elevated circulating levels of inflammatory cytokines in patients with abdominal aortic aneurysm. Arteriosd Thromb Vasc Biol 1997; 17:2843-7.
17. Treska V, Topolcan O, Pecen L. Cytokines as plasma markers of abdominal aortic aneurysm. Clin Chem Lab Med 2000; 38:1161-4.