Antisense inhibition of hyaluronan synthase-2 in human osteosarcoma cells inhibits hyaluronan retention and tumorigenicity

Experimental Cell Research

Volumn 307, Issue 1, 2005, Pages 194-203

  Nishida, Yoshihiro ^a   Knudson, Warren ^b   Knudson, Cheryl B ^b   Ishiguro, Naoki ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b RUSH MEDICAL COLLEGE   (United States)

Author keywords

Hyaluronan; Hyaluronan synthase; MG 63; Osteosarcoma

Indexed keywords

HYALURONAN SYNTHASE 2; HYALURONIC ACID; MESSENGER RNA; OLIGONUCLEOTIDE; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; CANCER INVASION; CARCINOGENICITY; CELL PROLIFERATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; INHIBITION KINETICS; OSTEOSARCOMA; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 19544383942     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2005.03.026     Document Type: Article

References (41)

1. M.P. Link, A.M. Goorin, A.W. Miser, A.A. Green, C.B. Pratt, J.B. Belasco, J. Pritchard, J.S. Malpas, A.R. Baker, J.A. Kirkpatrick, A.G. Ayala, J.J. Shuster, H.T. Abelson, J.V. Simone, and T.J. Veietti The effect of adjuvant chemotherapy on relapse-free survival in patients with osteosarcoma of the extremity N. Engl. J. Med. 314 1986 1600 1606
2. C.B. Knudson, and W. Knudson Hyaluronan-binding proteins in development, tissue homeostasis and disease FASEB J. 7 1993 1233 1241
3. W. Knudson Hyaluronan in malignancies T.C. Laurent The Chemistry, Biology and Medical Applications of Hyaluronan and its Derivatives 1998 Portland Press London, UK 169 179
4. B. Delpech, C. Maingonnat, N. Girand, C. Chauzy, R. Maunoury, A. Olivier, J. Tayot, and P. Creissard Hyaluronan and hyaluronectin in the extracellular matrix of human brain tumour stroma Eur. J. Cancer 29A 1993 1012 1017
5. L.P. Setala, M.I. Tammi, R.H. Tammi, M.J. Eskelinen, P.K. Lipponen, U.M. Agren, J. Parkkinen, E.M. Alhava, and V.M. Kosma Hyaluronan expression in gastric cancer cells is associated with local and nodal spread and reduced survival rate Br. J. Cancer 79 1999 1133 1138
6. K. Ropponen, M. Tammi, J. Parkkinen, M. Eskelinen, R. Tammi, P. Lipponen, U. Agren, E. Alhava, and V.M. Kosma Tumor cell-associated hyaluronan as an unfavorable prognostic factor in colorectal cancer Cancer Res. 58 1998 342 347
7. P. Auvinen, R. Tammi, J. Parkkinen, M. Tammi, U. Agren, R. Johansson, P. Hirvikoski, M. Eskelinen, and V.M. Kosma Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival Am. J. Pathol. 156 2000 529 536
8. R.T. Pirinen, R.H. Tammi, M.I. Tammi, P.K. Paakko, J.J. Parkkinen, U.M. Agren, R.T. Johansson, M.M. Viren, U. Tormanen, Y.M. Soini, and V.M. Kosma Expression of hyaluronan in normal and dysplastic bronchial epithelium and in squamous cell carcinoma of the lung Int. J. Cancer 79 1998 251 255
9. M.A. Anttila, R.H. Tammi, M.I. Tammi, K.J. Syrjanen, S.V. Saarikoski, and V.M. Kosma High levels of stromal hyaluronan predict poor disease outcome in epithelial ovarian cancer Cancer Res. 60 2000 150 155
10. K. Kimata, Y. Honma, M. Okayama, K. Oguri, M. Hozumi, and S. Suzuki Increased synthesis of hyaluronic acid by mouse mammary carcinoma cell variants with high metastatic potential Cancer Res. 43 1983 1347 1354
11. B. Yang, L. Zhang, and E.A. Turley Identification of two hyaluronan-binding domains in the hyaluronan receptor RHAMM J. Biol. Chem. 268 1993 8617 8623
12. W.H. McBride, and J.B.L. Bard Hyaluronidase sensitive halos around adherent cells J. Exp. Med. 149 1979 507 515
13. P.H. Weigel, V.C. Hascall, and M. Tammi Hyaluronan synthases J. Biol. Chem. 272 1997 13997 14000
14. A.P. Spicer, and J.A. McDonald Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family J. Biol. Chem. 273 1998 1923 1932
15. A.P. Spicer, M.F. Seldin, A.S. Olsen, N. Brown, D.E. Wells, N.A. Doggett, N. Itano, K. Kimata, J. Inazawa, and J.A. McDonald Chromosomal localization of the human and mouse hyaluronan synthase genes Genomics 41 1997 493 497
16. R. Kosaki, K. Watanabe, and Y. Yamaguchi Overproduction of hyaluronan by expression of the hyaluronan synthase Has2 enhances anchorage-independent growth and tumorigenicity Cancer Res. 59 1999 1141 1145
17. N. Itano, T. Sawai, O. Miyaishi, and K. Kimata Relationship between hyaluronan production and metastatic potential of mouse mammary carcinoma cells Cancer Res. 59 1999 2499 2504
18. N. Itano, T. Sawai, F. Atsumi, O. Miyaishi, S. Taniguchi, R. Kannagi, M. Hamaguchi, and K. Kimata Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncologic malignant transformation J. Biol. Chem. 279 2004 18679 18687
19. N. Liu, F. Gao, Z. Han, X. Xu, C.B. Underhill, and L. Zhang Hyaluronan synthase 3 overexpression promotes the growth of TSU prostate cancer cells Cancer Res. 61 2001 5207 5214
20. Y. Nishida, C.B. Knudson, J.J. Nietfeld, A. Margulis, and W. Knudson Antisense inhibition of hyaluronan synthase-2 in human articular chondrocytes inhibits proteoglycan retention and matrix assembly J. Biol. Chem. 274 1999 21893 21899
21. L.L. Faltz, C.B. Caputo, J.H. Kimura, J. Schrode, and V.C. Hascall Structure of the complex between hyaluronic acid, the hyaluronic acid-binding region, and the link protein of proteoglycan aggregates from the Swarm rat chondrosarcoma J. Biol. Chem. 254 1979 1381 1387
22. C.B. Knudson Hyaluronan receptor-directed assembly of chondrocyte pericellular matrix J. Cell Biol. 120 1993 825 834
23. K.M. Bullard, H.R. Kim, M.A. Wheeler, C.M. Wilson, C.L. Neudauer, M.A. Simpson, and J.B. McCarthy Hyaluronan synthase-3 is upregulated in metastatic colon carcinoma cells and manipulation of expression alters matrix retention and cellular growth Int. J. Cancer 107 2003 739 746
24. S.P. Evanko, and T.N. Wight Intracellular localization of hyaluronan in proliferating cells J. Histochem. Cytochem. 43 1999 1331 1341
25. Y. Nishida, A.L. D'Souza, E.J. Thonar, and W. Knudson Stimulation of hyaluronan metabolism by interleukin-1alpha in human articular cartilage Arthritis Rheum. 43 2000 1315 1326
26. V.C. Hascall, A.K. Majors, C.A. De La Motte, S.P. Evanko, A. Wang, J.A. Drazba, S.A. Strong, and T.N. Wight Intracellular hyaluronan: a new frontier for inflammation? Biochim. Biophys. Acta 1673 2004 3 12
27. R.M. Peterson, Q. Yu, I. Stamenkovic, and B.P. Toole Perturbation of hyaluronan interactions by soluble CD44 inhibits growth of murine mammary carcinoma cells in ascites Am. J. Pathol. 156 2000 2159 2167
28. A. Zoltan-Jones, L. Huang, S. Ghatak, and B.P. Toole Elevated hyaluronan production induces mesenchymal and transformed properties in epithelial cells J. Biol. Chem. 278 2003 45801 45810
29. S. Ghatak, S. Misra, and B.P. Toole Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway J. Biol. Chem. 277 2002 38013 38020
30. M. Hofmann, C. Fieber, V. Assmann, M. Gottlicher, J. Sleeman, R. Plug, N. Howells, O. von Stein, H. Ponta, and P. Herrlich Identification of IHABP, a 95 kDa intracellular hyaluronate binding protein J. Cell Sci. 111 1998 1673 1684
31. L. Collis, C. Hall, L. Lange, M. Ziebell, R. Prestwich, and E.A. Turley Rapid hyaluronan uptake is associated with enhanced motility: implications for an intracellular mode of action FEBS Lett. 440 1998 444 449
32. S.P. Evanko, J.C. Angello, and T.N. Wight Formation of hyaluronan- and versican-rich pericellular matrix is required for proliferation and migration of vascular smooth muscle cells Arterioscler., Thromb., Vasc. Biol. 19 1999 1004 1013
33. M.J. Park, M.S. Kim, I.C. Park, H.S. Kang, H. Yoo, S.H. Park, C.H. Rhee, S.I. Hong, and S.H. Lee PTEN suppresses hyaluronic acid-induced matrix metalloproteinase-9 expression in U87MG glioblastoma cells through focal adhesion kinase dephosphorylation Cancer Res. 62 2002 6318 6322
34. D. Zhu, and L.Y. Bourguignon Interaction between CD44 and the repeat domain of ankyrin promotes hyaluronic acid-mediated ovarian tumor cell migration J. Cell. Physiol. 183 2000 182 195
35. S.S. Bielack, B. Kempf-Bielack, G. Delling, G.U. Exner, S. Flege, K. Helmke, R. Kotz, M. Salzer-Kuntschik, M. Werner, W. Winkelmann, A. Zoubek, H. Jurgens, and K. Winkler Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols J. Clin. Oncol. 20 2002 776 790
36. D.B. Glasser, J.M. Lane, A.G. Huvos, R.C. Marcove, and G. Rosen Survival, prognosis, and therapeutic response in osteogenic sarcoma. The Memorial Hospital experience Cancer 69 1992 698 708
37. P.A. Meyers, G. Heller, J.H. Healey, A. Huvos, A. Applewhite, M. Sun, and M. LaQuaglia Osteogenic sarcoma with clinically detectable metastasis at initial presentation J. Clin. Oncol. 11 1993 449 453
38. W. Thorpe, W. Loeb, C. Hyatt, and S.A. Rosenberg Alkaline phosphatase measurements of paired normal and osteosarcoma tissue culture lines obtained from the same patient Cancer Res. 39 1979 277 279
39. R. Gorlick, A.G. Huvos, G. Heller, A. Aledo, G.P. Beardsley, J.H. Healey, and P.A. Meyers Expression of HER2/erbB-2 correlates with survival in osteosarcoma J. Clin. Oncol. 17 1999 2781 2788
40. N.A. Hernandez-Rodriguez, E. Correa, R. Sotelo, A. Contreras-Paredes, C. Gomez-Ruiz, L. Green, and A. Mohar Ki-67: a proliferative marker that may predict pulmonary metastases and mortality of primary osteosarcoma Cancer Detect. Prev. 25 2001 210 215
41. A.K. Raymond, A.G. Ayala, and S. Knuutila Conventional osteosarcoma P. Kleihues L. Sobin C. Fletcher K.K. Unni F. Mertens WHO Classification of Tumours: Pathology and Genetics of Tumours of Soft Tissue and Bone 2002 IARC Press Lyon, France 264 270